Molecular Neuroscience of Alcohol and Drug Abuse Research Training

酒精和药物滥用的分子神经科学研究培训

• 批准号: 10223173
• 负责人: Gary S. Aston-Jones
• 金额: $ 26.01万
• 依托单位: RUTGERS, THE STATE UNIV OF N.J.
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10223173
• 关键词: Alcohol abuse; Drug abuse; Molecular; Neurosciences; Research Training

The Rutgers molecular neuroscience of alcohol and drug abuse research training (MNADRT) program in New Jersey is designed to promote the development of promising postdoctoral research fellows as independent investigators and future University faculty members who will investigate the pathogenesis of alcoholism and drug abuse. The MNADRT will emphasize a multidisciplinary approach including molecular and cellular techniques, electrophysiology, optogenetics, designer receptors exclusively activated by designer drugs, stem cell technology, neuroimaging, neuroimmunology, neurobehavioral pharmacology, and genetics to increase the understanding of pathogenesis in alcoholism and drug abuse. Training of the postdoctoral fellows will be individualized with the most important component being the research conducted by the trainee in the faculty mentor's laboratory. In addition to hands-on alcohol and drug abuse research, additional training will include seminars and conferences, grant writing, responsible conduct of research, teaching and mentoring, scientific rigor and reproducibility and other training as needed to prepare fellows for independent research. The training faculty will consist of 10 funded investigators from multiple departments at Rutgers University. The trainees will benefit from the unique strengths of alcohol and drug abuse research at Rutgers University, which include the Endocrine Research Program, Brain Health Institute, Center of Alcohol Studies, and the research cores, including genome editing core facility, bioimaging core facility, genomic informatics and biostatics services. The vast resources of Rutgers provide state-of-the-art space, laboratory facilities, and equipment that support exceptional postdoctoral training. The training program will be directed by Drs. Dipak K. Sarkar and. Gary Aston-Jones and assisted by the Internal Advisory Committee consisted of 3 senior faculty members. Broader scientific inputs to the training will be provided by an External Advisory Committee consisting of four well- known alcohol and drug abuse researchers, Drs. Fulton Crews, Paula L. Hoffman, Fernando Valenzuela and Regina M. Carelli, who have substantial knowledge in NIAAA/NIDA training of postdoctoral fellows. The program proposes four post-doctoral fellow slots. Trainees will receive two years of research training and with external support sought for later years. This institutional training grant will promote intensive training in molecular, cellular, immunological, stem cell technology, imaging techniques and basic neuroscience and neuroendocrinology in a stimulating environment leading to broadly trained independent investigators capable of adapting to the rapid advances in research in the 21st century.

罗格斯大学酒精和药物滥用研究培训（MNADRT）计划在纽约 泽西岛的目的是促进有前途的博士后研究员作为独立的发展 研究人员和未来的大学教师谁将调查酗酒的发病机制， 吸毒MNADRT将强调多学科方法，包括分子和细胞 技术、电生理学、光遗传学、专门由设计药物激活的设计受体、干细胞 细胞技术、神经影像学、神经免疫学、神经行为药理学和遗传学， 对酒精中毒和药物滥用发病机制的认识。博士后研究员的培训将是 个性化与最重要的组成部分是由受训者在教师进行的研究 导师的实验室除了动手酒精和药物滥用研究，额外的培训将包括 研讨会和会议，赠款写作，负责任的研究行为，教学和指导，科学 严格性和可重复性以及为研究员进行独立研究做好准备所需的其他培训。培训 教师将由来自罗格斯大学多个部门的10名受资助的研究人员组成。学员将 受益于罗格斯大学酒精和药物滥用研究的独特优势，其中包括 内分泌研究计划，脑健康研究所，酒精研究中心，和研究核心， 包括基因组编辑核心设施、生物成像核心设施、基因组信息学和生物统计学服务。的 罗格斯大学的大量资源提供了最先进的空间、实验室设施和设备， 优秀的博士后培训。培训计划将由Dipak K博士指导。萨卡和。加里 阿斯顿-琼斯和内部咨询委员会的协助下，由3名高级教员组成。更广泛 培训的科学投入将由一个外部咨询委员会提供，该委员会由四个成员组成， 已知的酒精和药物滥用研究人员，富尔顿克鲁斯博士，保拉L。霍夫曼、费尔南多·巴伦苏埃拉和 Regina M. Carelli，他们在NIAAA/NIDA博士后研究员培训方面有丰富的知识。的 计划提出四个博士后研究员插槽。学员将接受两年的研究培训， 今后几年寻求外部支持。这一机构培训赠款将促进以下方面的强化培训： 分子、细胞、免疫学、干细胞技术、成像技术和基础神经科学， 神经内分泌学在一个刺激的环境，导致广泛培训的独立调查人员能够 以适应世纪研究的快速发展。