Living Donor Wage Reimbursement Trial

活体捐赠者工资报销试验

基本信息

  • 批准号:
    10223276
  • 负责人:
  • 金额:
    $ 25.71万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2017
  • 资助国家:
    美国
  • 起止时间:
    2017-08-01 至 2023-07-31
  • 项目状态:
    已结题

项目摘要

PROJECT SUMMARY / ABSTRACT The waiting list for kidney transplantation (KT) now exceeds 100,000 and waiting times exceed 7 yrs in some U.S. regions. Live donor kidney transplantation (LDKT) accelerates the path to transplantation and yields superior outcomes compared to dialysis and deceased donor KT. However, the annual number of LDKTs has declined over the last decade, particularly among minority and low-income patients. We hypothesize, and have preliminary data to support, that the financial impact on living donors (LDs) is a major contributor to the LDKT decline and for persistent racial disparities in LDKT rates. Many LDs have substantial non-reimbursed direct and indirect costs, most notably the loss of income or wages following surgery. In this study, we will: (1) evaluate the effectiveness of offering reimbursement for LD lost wages on the LDKT rate; (2) examine whether offering reimbursement for LD lost wages reduces known racial disparities in LDKT; and (3) determine whether study outcomes differ significantly by maximum reimbursement amount for LD lost wages. To accomplish these aims, we will conduct a blended randomized trial and matched historical control study with a planned enrollment of 350 KT candidates who will be randomized to one of two parallel arms: (1) possible reimbursement of LD lost wages up to $1,500 (LW-1.5), or (2) possible reimbursement of LD lost wages up to $3,000 (LW-3.0). Our central hypotheses are that offering reimbursement for LD lost wages will (a) yield higher LDKT rates overall relative to matched historical controls, and (b) reduce the disparity between LDKT rates in white and minority patients relative to historical patterns. Also, we hypothesize that KT candidates who are offered up to $3,000 reimbursement for LD lost wages will have a higher likelihood of LDKT compared to those offered up to $1,500 of reimbursement for LD lost wages. Finally, we will assess the impact of offering reimbursement for LD lost wages on the decision-making of both KT candidates and potential LDs as well as perceptions of pressure/coercion and decision stability. Overall, the proposed study will be the first to empirically examine the impact of offering LD lost wages reimbursement on the willingness of KT candidates to pursue LDKT, racial disparity in LDKT, rates of LD evaluations, and actual LDKT rates. Moreover, this study will be the first to examine the differential impact on these outcomes of offering to reimburse LD lost wages for different amounts ($1,500 vs. $3,000) after donation. As such, findings from this study have very high potential to impact policy, clinical practice, LDKT access, and known income and racial disparities in KT. The assembled interdisciplinary research team has a long track record of collaboration and is internationally recognized for developing innovative strategies to increase LDKT access in disadvantaged patient populations, extramural funding to conduct large RCTs and multi-center studies, and dissemination of research findings with broad policy and clinical practice implications.
项目摘要/摘要

项目成果

期刊论文数量(4)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Opinions of African American adults about the use of apolipoprotein L1 (ApoL1) genetic testing in living kidney donation and transplantation.
Apolipoprotein L1 Opinions of African American Living Kidney Donors, Kidney Transplant Patients, and Nonpatients.
非裔美国活体肾脏捐赠者、肾移植患者和非患者对载脂蛋白 L1 的看法。
  • DOI:
    10.1016/j.jss.2022.04.011
  • 发表时间:
    2022
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Harris,DwightD;Fleishman,Aaron;Pavlakis,Martha;Pollak,MartinR;Baliga,PrabhakarK;Rohan,Vinayak;Kayler,LiiseK;Rodrigue,JamesR
  • 通讯作者:
    Rodrigue,JamesR
The Living Donor Lost Wages Trial: Study Rationale and Protocol.
活体捐赠者工资损失试验:研究原理和方案。
  • DOI:
  • 发表时间:
    2018
  • 期刊:
  • 影响因子:
    2.1
  • 作者:
    Rodrigue,JamesR;Fleishman,Aaron;Carroll,Michaela;Evenson,AmyR;Pavlakis,Martha;Mandelbrot,DidierA;Baliga,Prabhakar;Howard,DavidH;Schold,JesseD
  • 通讯作者:
    Schold,JesseD
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James R Rodrigue其他文献

James R Rodrigue的其他文献

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{{ truncateString('James R Rodrigue', 18)}}的其他基金

Living Donor Wage Reimbursement Trial
活体捐赠者工资报销试验
  • 批准号:
    9980402
  • 财政年份:
    2017
  • 资助金额:
    $ 25.71万
  • 项目类别:
House Calls and Decision Support: Increasing Access to Live Donor Transplantation
出诊和决策支持:增加活体捐赠者移植的机会
  • 批准号:
    8500744
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
House Calls and Decision Support: Increasing Access to Live Donor Transplantation
出诊和决策支持:增加活体捐赠者移植的机会
  • 批准号:
    8550042
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
House Calls and Decision Support: Increasing Access to Live Donor Transplantation
出诊和决策支持:增加活体捐赠者移植的机会
  • 批准号:
    8724959
  • 财政年份:
    2012
  • 资助金额:
    $ 25.71万
  • 项目类别:
A Randomized Trial and Reduce to Disparity in Live Donor Kidney Transplantation
随机试验并减少活体肾移植的差异
  • 批准号:
    8054120
  • 财政年份:
    2010
  • 资助金额:
    $ 25.71万
  • 项目类别:
A Randomized Trial and Reduce to Disparity in Live Donor Kidney Transplantation
随机试验并减少活体肾移植的差异
  • 批准号:
    7337417
  • 财政年份:
    2007
  • 资助金额:
    $ 25.71万
  • 项目类别:
A Randomized Trial and Reduce to Disparity in Live Donor Kidney Transplantation
随机试验并减少活体肾移植的差异
  • 批准号:
    7670182
  • 财政年份:
    2007
  • 资助金额:
    $ 25.71万
  • 项目类别:
A Randomized Trial and Reduce to Disparity in Live Donor Kidney Transplantation
随机试验并减少活体肾移植的差异
  • 批准号:
    7917434
  • 财政年份:
    2007
  • 资助金额:
    $ 25.71万
  • 项目类别:
A Randomized Trial and Reduce to Disparity in Live Donor Kidney Transplantation
随机试验并减少活体肾移植的差异
  • 批准号:
    8121444
  • 财政年份:
    2007
  • 资助金额:
    $ 25.71万
  • 项目类别:
Quality of Life Therapy for Adults with ESRD Awaiting Renal Transplantation
等待肾移植的终末期肾病成人的生活质量治疗
  • 批准号:
    7216605
  • 财政年份:
    2006
  • 资助金额:
    $ 25.71万
  • 项目类别:

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