Adaptive Platform for Personalized Engagement

项目摘要/摘要 PMI队列计划(PMI-CP)将建立一个由100万或更多美国志愿者组成的全国性研究队列 他们作为合作伙伴参与了一项纵向努力，以转变对有助于 个人健康和疾病。根据精确医学倡议(PMI)工作组报告(PMI-WGR) 建议3.3：所有居住在美国的个人都应该能够为PMI队列做志愿者。作为一名 作为以患者为中心的研究的长期支持者，Vibrent了解Participant Technology Center PMI协作的(PTC)部分是关键任务。参与者必须通过互联网参与 启用体验，并保持参与度。这项提议提供了这样一种方法，即参与、鼓励 激励、保留和维持一支具有全国代表性的队伍。该提案使用了当前的技术 例如移动电话、网站和功能电话，以实现PMI队列方案的目标，如 并支持不断发展的消费技术，如无线传感器、可穿戴设备和不断发展的 平衡创新与稳健性和可扩展性的科学。 我们正在通过参与和保留三合一模式提出一种创新和强大的方法。 参与者参与度和赋权是PMI-CP的核心价值，我们的PTC方法将 利用PCORI参与原则支持和促进参与者和研究人员之间的伙伴关系。 我们的建议将部署一个由三大支柱--技术、科学和支持--支持的基础设施 以便参与、维持和扩大队列。每一个支柱都将通过一个过程不断完善 “测量-学习-迭代”。这将实现适应性和个性化，以确保 PMI计划。 通过参与合作研究项目和大型财团，我们的团队拥有 通过以下四个组件的一致性、集成性和协同性来提供管理的专业知识 PMI-CP(PTC、CC、HPO、生物库)。我们将为参与者参与提供基础设施，并 将在深度和广度上扩展的沟通。

Project Summary/Abstract The PMI Cohort Program (PMI-CP) will build a national research cohort of one million or more U.S. volunteers who are engaged as partners in a longitudinal effort to transform the understanding of factors contributing to individual health and disease. Per the Precision Medicine Initiative (PMI) Working Group Report (PMI-WGR) Recommendation 3.3: All individuals living in the U.S. should be able to volunteer for the PMI cohort. As a long-time proponent of patient-centered research, Vibrent understands that the Participant Technology Center (PTC) component of the PMI collaboration is mission critical. Participants must be engaged through internet enabled experiences and remain engaged. This proposal provides such an approach to Engage, Encourage, Motivate, Retain and Sustain a nationally representative Cohort. The proposal uses current technologies such as mobile phones, website and feature phones to achieve the objectives of the PMI Cohort Program as well as allow for evolving consumer technologies such as wireless sensors, wearables and evolving science that balance innovation with robustness and scalability. We are proposing an innovative and robust approach through an Engagement and Retention Triad Model. Participant engagement and empowerment are core values for the PMI-CP and our PTC approach would enable and promote partnership between participants and researchers using PCORI Engagement Principles. Our proposal will deploy an infrastructure supported by the three pillars – Technology, Science and Support in order to engage, sustain and scale the cohort. Each pillar will continuously improve through a process of “measure-learn-iterate”. This will enable adaptability and personalization to ensure long term success of the PMI program. Through participation in collaborative research projects and large-scale consortiums, our team has the expertise to provide stewardship through coherence, integration, and synergy across the four components of the PMI-CP (PTC, CC, HPO, biobank). We will provide the infrastructure for participant engagement and communication that will scale in depth and breadth.