FASEB's The Ion Channel Regulation Conference

FASEB 离子通道调节会议

• 批准号: 10231849
• 负责人: Isabelle Deschenes
• 金额: $ 1.5万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10231849
• 关键词: Academia; Accounting; Address; Area; Arrhythmia; Asia; Asthma; Basic Science; Biology; Blindness; Canada; Cell physiology; Cells; Collaborations; Communities; Computer Models; Cystic Fibrosis; Development; Diabetes Mellitus; Discipline; Disease; Doctor of Philosophy; Epilepsy; Europe; Faculty; Financial Support; Fluid Balance; Fostering; Functional disorder; Future; Gene Expression; General Population; Genes; Goals; Grant; Heart; Hereditary Disease; Hormone secretion; Human; Human Genome; Hypertension; Image; Industry; International; Investigation; Ion Channel; Ions; Irritable Bowel Syndrome; Island; Knowledge; Link; Membrane Proteins; Methods; Migraine; Morbidity - disease rate; Muscle Contraction; Mutation; Neurons; Nova Scotia; Ohio; Organ; Organelles; Pain; Parkinson Disease; Participant; Pharmaceutical Preparations; Physiological; Physiological Processes; Play; Population; Private Sector; Proteomics; Public Health; Regulation; Research; Research Personnel; Resort; Role; Science; Scientific Advances and Accomplishments; Scientist; Seeds; Signal Transduction; Skin Cancer; Stomach; Structure; Synaptic Transmission; Therapeutic; Time; Transcriptional Regulation; Translations; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Universities; Virginia; Woman; autism spectrum disorder; career; career development; chronic pain; cross disciplinary program; deafness; disease-causing mutation; drug development; frontier; human disease; innovation; meetings; member; mortality; multidisciplinary; nervous system disorder; neurotransmission; peer; periodic paralysis; precision medicine; prevent; programs; skin disorder; sudden cardiac death; symposium; synergism; therapeutic development; trafficking

This is an application for partial support of the 10th biennial FASEB Science Research Conference on Ion Channel Regulation that will be held from June 27 to July 2 2021 at the Oak Island Resort & Conference Center in Nova Scotia, Canada. The objectives of this conference are to: stimulate discourse, seed new ideas, and facilitate collaboration in ways that will accelerate new discoveries about ion channels at the basic and translational levels, and to provide a forum for trainees to participate in scientific sessions and in career development activities. Regulation of ion channel function is essential for myriad physiological functions including neuronal signaling, pain transduction, and the beating of the heart. Accounting for ~2% of human genes, ion channels are subject to numerous disease-causing mutations, leading to over 55 inherited disorders termed “channelopathies”, including epilepsy, migraine, several neurological disorders, blindness, deafness, diabetes, hypertension, several different cardiac arrhythmias, asthma, irritable bowel syndrome, skin diseases and cancer. Importantly, considering the central involvement of ion channels, these diseases share a great deal in common in terms of disease mechanisms and potential therapeutic development with ion channels being the target of numerous drugs. Thus, the topic of our conference is both timely and highly relevant for a broad population of scientists, clinicians, and the general public and will benefit greatly from the ion channel community coming together. The meeting will be co-chaired by Isabelle Deschênes from The Ohio State University and Gea-Ny Tseng from Virginia Commonwealth University, both recognized leaders in ion channel biology with expertise between the two of them covering all aspects of ion channel research going from structure-function, transcriptional regulation, trafficking, regulation and channelopathies. The Program consists of nine scientific sessions, two keynote addresses, and two breakout sessions focused on interactions with experts from academia, NIH and industry and a career development session. Most scientific sessions are organized around general themes rather than ion channel subtype and organs, to foster crosstalk between fields typically kept separate in traditional conferences. There will be 32 session speakers giving full talks, including at least 18 women (56% of speakers) and 9 session chairs (4 of whom are women, 44%). Most of the invited speakers (90%) have not presented at this conference during the prior two meetings. Of the 32 session speakers, we currently have 9 early career stage investigators (28%) and 9 members of under-represented minorities in science (28%). We will also have 8 additional short talks which will be selected from the abstracts submitted and dedicated to junior investigators which will therefore encompass 36% of our speakers, giving them the opportunity to get broad exposure. We have placed emphasis on comprehensive scientific themes shared across ion channel types seeking to catalyze on the knowledge from each to benefit the broader field and will allow us to build multidisciplinary networks across the different ion channels.

这是第10届两年一度的FASEB离子科学研究会议的部分支持申请 渠道监管将于2021年6月27日至7月2日在橡树岛度假村和会议中心举行 在加拿大的新斯科舍省。本次会议的目标是：激发话语，播种新的想法， 促进合作的方式，将加快新的发现离子通道的基础和 翻译水平，并为学员提供一个论坛，参加科学会议和职业生涯 发展活动。离子通道功能的调节对于多种生理功能是必不可少的， 神经信号传导、疼痛传导和心脏跳动。离子约占人类基因的2% 通道受到许多致病突变，导致超过55种遗传性疾病，称为 “通道病”，包括癫痫、偏头痛、几种神经系统疾病、失明、耳聋、糖尿病， 高血压、几种不同的心律失常、哮喘、肠易激综合症、皮肤病和癌症。 重要的是，考虑到离子通道的中心参与，这些疾病有很多共同点 在疾病机制和潜在的治疗发展方面，离子通道是 许多药物。因此，我们会议的主题对广大人民来说是及时和高度相关的， 科学家，临床医生和公众，并将大大受益于离子通道社区的到来 一起会议将由来自俄亥俄州州立大学和Gea-Ny的Isabelle Deschênes共同主持 来自弗吉尼亚联邦大学的Tseng，两人都是公认的离子通道生物学领域的领导者， 它们之间的联系涵盖了离子通道研究的各个方面，从结构-功能， 转录调节、运输、调节和通道病。该计划包括9个科学 会议，两个主题演讲和两个分组会议，重点是与来自 学术界、NIH和工业界以及职业发展会议。大多数科学会议都是围绕 一般的主题，而不是离子通道亚型和器官，以促进场之间的串扰通常保持 在传统的会议中分开。将有32个会议发言人进行充分的演讲，其中包括至少18个 妇女（56%的发言者）和9名会议主席（其中4名为妇女，占44%）。大部分受邀演讲者 (90在前两次会议期间未在本次会议上发言的国家占30%。在32位发言人中，我们 目前有9名职业早期阶段的调查员（28%）和9名代表性不足的少数民族成员， 科学（28%）。我们还将有8个额外的简短会谈，将从提交的摘要中选出， 致力于初级调查员，因此将涵盖我们36%的发言者， 有机会获得广泛的曝光。我们强调跨学科共享的综合科学主题， 离子通道类型寻求催化的知识，从每一个受益于更广泛的领域，并将使我们 在不同的离子通道上建立多学科网络。