Building Interdisciplinary Research in Women's Health

项目摘要 这是杜兰BIRCWH计划的竞争更新申请，该计划已成功培训了一名 一群种族/族裔和专业多样的妇女健康和 在过去的4年里，杜兰大学提高了对妇女健康研究的认识。我们现在建议， 我们先前的成功，扩大和加强BIRCWH计划基础。长期目标是增加 受过高度培训的文化能力强、独立、跨学科的调查人员的数量和多样性， 妇女健康，重点是心血管疾病（CVD）领域的性别差异研究 和相关疾病。该计划的重点是心血管疾病和相关疾病，因为心脏病的影响， 缓解妇女，现有的知识差距的性别差异，心血管疾病的研究范围， 以及杜兰大学这种专注的力量。我们成功的职业发展计划的关键组成部分包括 1)针对特定学者需求的教学课程; 2）个性化的职业发展培训; 3） BIRCWH系列研讨会; 4）正在进行的工作会议; 5）所需的赠款写作和项目管理 讲习班; 6）指导跨学科研究; 7）负责任的研究培训行为;和8）Incuberu- 国家资源。创新的方法包括使用自我效能感来定制学生的需求 评估和职业发展计划，并为每个学者使用网络辅导模式，包括 在基础科学和临床研究方面的专业知识。学者们立即接触到研究， 引导建立一个学术跟踪记录早期，并获得演示和组织技能的积极参与， 健康科学研究日-妇女健康/性别差异部分。的新组件 增强的BIRCWH计划包括更多的教师参与新的学科，包括BIRCWH 校友，导师和学者的导师培训，严谨性，可重复性，透明度和性别的整合， 生物变量培训，加强与泽维尔的合作，泽维尔是一个历史上的黑人，研究密集度较低， 该机构，并计划为学者提供生物医学研究卓越中心的管道。学校- ars将学习前沿的研究方法和技能，从Bench（细胞，分子和遗传学），到Bed- 从临床研究和临床试验到人口（流行病学、预防和卫生服务）， 搜索），并进行自己的研究项目，在既定的实验室/研究小组在一个指导， 跨学科的环境，解决最新的ORWH优先事项。学者的跨学科研究- 搜索将集中在心血管疾病和相关疾病及其危险因素的性别差异，并解决overarch- 研究主题（寿命、性/性别决定因素、健康差异和跨学科研究）。我们提出 培训6名教员学者，至少2-3年（医生-科学家至少3年）。正在进行和 全面的评估将指导改进该计划在桥接方面的已证明的有效性 为年轻科学家提供研究培训和研究独立性，重点是性别差异和心血管疾病。

Project Summary This is a competing renewal application for the Tulane BIRCWH Program, which has successfully trained a racially/ethnically and professionally diverse group of interdisciplinary researchers in women's health and in- creased awareness of women's health research at Tulane over the last 4 years. We propose now to build on our prior success and expand and reinforce the BIRCWH program base. The long-term goal is to increase the number and diversity of highly trained culturally competent, independent, interdisciplinary investigators in Women's Health with an emphasis on Sex Differences research in the field of cardiovascular disease (CVD) and related diseases. The program focuses on CVD and related diseases because of the impacts of heart dis- ease on women, the existing knowledge gaps on the sex differences in CVD across the research spectrum, and the strength of this focus at Tulane. Key components of our successful career development plan include 1) didactic courses tailored to specific Scholar needs; 2) individualized career development training; 3) BIRCWH seminar series; 4) Work-in-Progress sessions; 5) required grant writing and project management workshops; 6) mentored interdisciplinary research; 7) responsible conduct in research training; and 8) institu- tional resources. The innovative approach includes tailoring the program to Scholars needs using self-efficacy assessment and career development plans, and using a network mentoring model for each Scholar, including expertise in both basic science and clinical research. Scholars are immediately exposed to research and are guided to establish a scholarly track record early, and gain presentation and organization skills by active partic- ipation in the Health Sciences Research days-Women's Health/Sex Differences Section. New components of the enhanced BIRCWH program include additional faculty participation in new disciplines including BIRCWH alumni, mentor training for Mentors and Scholars, integration of rigor, reproducibility, transparency, and sex as a biologic variable training, strengthened collaboration with Xavier, a historically Black, less-research-intensive institution, and a planned pipeline for Scholars to the Centers of Biomedical Research Excellence. The Schol- ars will learn cutting-edge research methods and skills from Bench (cellular, molecular, and genetics), to Bed- side (clinical research and clinical trials) to Population (epidemiology, prevention, and health services re- search) and conduct their own research projects in established laboratories/research groups in a mentored, interdisciplinary environment that address the most recent ORWH priorities. Scholar's interdisciplinary re- search will focus on sex differences in CVD and related diseases and their risk factors and address overarch- ing themes (lifespan, sex/gender determinants, health disparities, and interdisciplinary research). We propose to train 6 faculty Scholars for a minimum of 2-3 years (3 years minimum for physician-scientists). Ongoing and comprehensive evaluation will guide improvements to the program's demonstrated effectiveness in bridging research training and research independence for junior scientists focused on Sex Differences and CVD.