Building Interdisciplinary Research in Women's Health

项目摘要 这是杜兰BIRCWH计划的竞争续订申请，该计划已成功培训了 在种族/族裔和专业上不同的妇女健康跨学科研究人员群体-- 在过去的4年里，杜兰大学提高了对妇女健康研究的认识。我们现在建议在此基础上 我们以往的成功，扩大和加强了BIRCWH项目基础。长期目标是增加 受过高度培训的具有文化能力的独立跨学科调查员的数量和多样性 关注心血管疾病领域性别差异的女性健康研究 以及相关的疾病。该计划侧重于心血管疾病和相关疾病，因为心脏疾病的影响。 对女性的宽容，在整个研究范围内关于心血管疾病性别差异的现有知识差距， 以及杜兰大学这种专注的力量。我们成功的职业发展计划的关键组成部分包括 1)为特定学者需求量身定做的教学课程；2)个性化职业发展培训；3) BIRCWH系列研讨会；4)正在进行的会议；5)需要编写赠款和项目管理 研讨会；6)指导跨学科研究；7)研究培训中负责任的行为；8)组织-- 国家资源。创新的方法包括使用自我效能感根据学者的需求定制计划 评估和职业发展计划，并对每个学者使用网络辅导模式，包括 在基础科学和临床研究方面的专业知识。学者们立即接触到研究，并 指导及早建立学术记录，并通过积极的小组-获得演讲和组织技能- 健康科学研究日--妇女健康/性别差异部分。的新组件 增强的BIRCWH计划包括更多的教师参与新的学科，包括BIRCWH 校友，导师和学者的导师培训，将严谨、可重复性、透明度和性别作为 一次生物变量培训，加强了与历史上黑人、研究密集度较低的泽维尔的合作 机构，并计划为学者提供通往生物医学研究卓越中心的管道。学校-- ARS将学习尖端的研究方法和技能，从BASE(细胞、分子和遗传学)，到BEED- 从(临床研究和临床试验)到人口(流行病学、预防和卫生服务) 搜索)，并在现有实验室/研究小组指导下进行自己的研究项目， 跨学科环境，解决最新的ORWH优先事项。学者的跨学科再认识 Search将重点关注心血管疾病和相关疾病的性别差异及其风险因素，并解决主要问题- ING主题(寿命、性/性别决定因素、健康差距和跨学科研究)。我们建议 培训6名院士，最少2-3年(内科科学家最少3年)。持续和 综合评估将指导改进该计划在桥接方面已证明的有效性 初级科学家的研究培训和研究独立性侧重于性别差异和心血管疾病。

Project Summary This is a competing renewal application for the Tulane BIRCWH Program, which has successfully trained a racially/ethnically and professionally diverse group of interdisciplinary researchers in women's health and in- creased awareness of women's health research at Tulane over the last 4 years. We propose now to build on our prior success and expand and reinforce the BIRCWH program base. The long-term goal is to increase the number and diversity of highly trained culturally competent, independent, interdisciplinary investigators in Women's Health with an emphasis on Sex Differences research in the field of cardiovascular disease (CVD) and related diseases. The program focuses on CVD and related diseases because of the impacts of heart dis- ease on women, the existing knowledge gaps on the sex differences in CVD across the research spectrum, and the strength of this focus at Tulane. Key components of our successful career development plan include 1) didactic courses tailored to specific Scholar needs; 2) individualized career development training; 3) BIRCWH seminar series; 4) Work-in-Progress sessions; 5) required grant writing and project management workshops; 6) mentored interdisciplinary research; 7) responsible conduct in research training; and 8) institu- tional resources. The innovative approach includes tailoring the program to Scholars needs using self-efficacy assessment and career development plans, and using a network mentoring model for each Scholar, including expertise in both basic science and clinical research. Scholars are immediately exposed to research and are guided to establish a scholarly track record early, and gain presentation and organization skills by active partic- ipation in the Health Sciences Research days-Women's Health/Sex Differences Section. New components of the enhanced BIRCWH program include additional faculty participation in new disciplines including BIRCWH alumni, mentor training for Mentors and Scholars, integration of rigor, reproducibility, transparency, and sex as a biologic variable training, strengthened collaboration with Xavier, a historically Black, less-research-intensive institution, and a planned pipeline for Scholars to the Centers of Biomedical Research Excellence. The Schol- ars will learn cutting-edge research methods and skills from Bench (cellular, molecular, and genetics), to Bed- side (clinical research and clinical trials) to Population (epidemiology, prevention, and health services re- search) and conduct their own research projects in established laboratories/research groups in a mentored, interdisciplinary environment that address the most recent ORWH priorities. Scholar's interdisciplinary re- search will focus on sex differences in CVD and related diseases and their risk factors and address overarch- ing themes (lifespan, sex/gender determinants, health disparities, and interdisciplinary research). We propose to train 6 faculty Scholars for a minimum of 2-3 years (3 years minimum for physician-scientists). Ongoing and comprehensive evaluation will guide improvements to the program's demonstrated effectiveness in bridging research training and research independence for junior scientists focused on Sex Differences and CVD.