Vision Sciences Training Grant

摘要 请求支助每年培训5个博士前实习生职位，在整个大学范围内开设视觉科学课程 系统、细胞和分子层面的培训计划。36名教师导师的培训重点是 对正常和疾病眼睛的视觉处理以及细胞、分子和遗传学方面的分析 包括基础科学和以疾病为导向的研究。25名教员从事系统和计算方面的工作 人类、非人类灵长类动物和其他模型系统中的视觉和眼球运动系统，使用 神经生理学、心理物理学、行为分析、脑成像和计算建模(第1节)。 第二部分(发育和可塑性)的六名教师专注于视网膜细胞规范和轴突指导 发育，血-视网膜屏障，以及皮质树突和回路的生物物理学和可塑性。八 教职员工的研究项目涉及正常和疾病眼睛的分子/遗传学方法 (第3节)主要研究视网膜变性、视黄醇的加工，以及遗传学、诊断和 视网膜疾病的治疗，重点是老年性黄斑变性和视网膜水肿。虽然 导师在不同的系(生物科学、心理学、统计学、生物医学工程和 晨兴校园的放射学、生态学、进化论和环境生物学；神经科学 以及遗传学、眼科学、病理学和细胞生物学、神经学、医学和 医学院校园里的儿科，在跨学科主题上的多项合作通常支持 培训和视力进步导师和学员进行的研究符合以下目标 NEI的眼睛和视觉研究战略计划，包括大胆的目标倡议和2020年远景 未来。为选择实验室和导师的博士前学生寻求长达三年的支持 在视力研究方面。与视觉科学相关的论文项目的实习生是从 研究生课程，如神经生物学和行为学博士课程，以及 细胞、分子和生物医学科学，这两个学科都有医学博士研究生。通过活动，如 教学课程，严谨和可再生性培训，论文委员会，座谈会，研讨会，以及 纽约视觉俱乐部(VisioNYC)，预计教职员工和实习生将互动、合作和产生 新一代视觉科学家将阐明信息处理、发育和疾病 视觉系统。

Summary Support is requested for training of 5 predoctoral trainee positions per year, in a university-wide visual science training program at the systems, cellular, and molecular level. Training by thirty-six faculty mentors focuses on analysis of visual processing, and cellular, molecular and genetic aspects of the normal and diseased eye, in both basic science and disease-oriented research. Twenty-five faculty work in Systems and Computation on the visual and oculomotor systems in humans, non-human primates, and other model systems, using neurophysiology, psychophysics, behavioral analysis, brain imaging, and computational modeling (Section 1). Six faculty in Section 2 (Development and Plasticity) focus on retinal cell specification and axon guidance, eye development, the blood-retina barrier, and biophysics and plasticity of cortical dendrites and circuitry. Eight faculty have research programs that touch on Molecular/genetic Approaches to the Normal and Diseased Eye (Section 3) with primary interests in retinal degeneration, retinoid processing, and the genetics, diagnostics and therapy of retinal disorders, with a focus on age-related macular degeneration and retinal edema. Although mentors are in different departments (Biological Sciences, Psychology, Statistics, Biomedical Engineering and Radiology, Ecology, Evolution and Environmental Biology on the Morningside campus; Neuroscience on the Manhattanville campus; and Genetics, Ophthalmology, Pathology & Cell Biology, Neurology, Medicine and Pediatrics on the medical school campus, multiple collaborations on interdisciplinary themes routinely support training and advances on vision The research carried out by the mentors and trainees matches the goals in NEI’s strategic plan for eye and vision research, including the Audacious Goals Initiative and 2020 Vision for the Future. Suppport is sought for up to three years for predoctoral students who have chosen their lab and mentor in vision studies. Trainees working on thesis projects related to the vision sciences are selected from selective graduate programs such as the Doctoral Program in Neurobiology and Behavior, and Integrated Program in Cellular, Molecular and Biomedical Sciences, both of which host MD-PhD students. Through activities such as didactic courses, training in rigor and reproducabilty, thesis committees, symposia, seminars, and the Greater New York Vision Club (VisioNYC), it is expected that faculty and trainees will interact, collaborate, and produce a new generation of vision scientists who will elucidate information processing, development, and diseases of the visual system.