Exploring the concept of dyadic health in Thai couples coping with breast cancer: A preliminary study of a partnered approach to physical activity in breast cancer survivors and spouse care partners

探索泰国夫妇应对乳腺癌的二元健康概念：乳腺癌幸存者和配偶护理伙伴合作体育活动方法的初步研究

• 批准号: 10426561
• 负责人: KERRI M WINTERS-STONE
• 金额: $ 14.22万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-04-01 至 2022-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10426561
• 关键词: Address; Adherence; Administrative Supplement; Adoption; Aftercare; Area; Breast Cancer survivor; Cancer Center; Cancer Hospital; Cancer Patient; Cancer Survivor; Cancer Survivorship; Caregivers; Caring; Collaborations; Country; Couples; Data; Discipline of Nursing; Emotional; Exercise; Face; Family Caregiver; Feasibility Studies; Funding; Goals; Health; Health Professional; Health Promotion; Health behavior; Income; Individual; Institution; Intervention; Intervention Studies; Investigation; Lead; Learning; Maintenance; Medical; Mental Health; Methods; Outcome; Parents; Patients; Personal Satisfaction; Phase; Physical activity; Quality of life; Research; Research Personnel; Resources; Risk; Sampling; Services; Social support; Spouse Caregiver; Spouses; Supportive care; Survivors; System; Testing; Thailand; Universities; Woman; Work; behavior change; cancer care; cancer diagnosis; coping; efficacy trial; evidence base; exercise program; expectation; follow-up; health management; high risk; improved; improved outcome; informal caregiver; interest; loved ones; malignant breast neoplasm; member; novel strategies; parent grant; physical conditioning; preference; programs; psychologic; psychosocial; survivorship; virtual

The proposed supplement application responds to the Notice of Special Interest (NOSI) identified in NOT-CA- 21-058 for projects to stimulate and strengthen global cancer survivorship research. The parent grant is an efficacy trial to determine the benefits of dyadic exercise (e.g., both patients and spouses together) to optimize physical, emotional and relationship health among cancer survivors and their spouse care partners. The parent trial (R01CA218093) focuses on dyadic health of both patients and their spouses, often informal caregivers, who are in turn at higher risk of poor outcomes than spouses who do not care for an ill loved one. Improving health behaviors, such as physical activity, can have a substantial impact on quality of life and survival in cancer survivors and their partners, but most cancer survivors have low rates of physical activity while the health of partners is virtually ignored. Patients living in low to middle income countries (LMIC) face many barriers to exercise, including a lack of supportive care programs specific to the unique needs of cancer patients and a lack of social support to promote behavior change and maintenance. We include the spouse to promote patient retention and adherence to exercise through social support, but also by participating in exercise as well the spouse themselves can also benefit from becoming more physically active. We are proposing build upon an existing relationship between the parent trial’s institution with Mahidol University and the Siriraj Hospital Cancer Center to explore the concept of dyadic health and pilot test an adaption of the parent trial’s dyadic health management strategy to promote physical activity among breast cancer survivors and their spouse care partners. We will conduct a two-phase project, starting with a mixed-methods investigation to assess dyadic adjustment and dyadic health among Thai couples coping with breast cancer and their interest and preferences for a dyadic physical activity program. Data gathered from the first phase will be used to develop and pilot a culturally specific dyadic physical activity program in a sample of Thai couples. The proposed project will stimulate a new collaboration between investigators from the parent trial and investigators and clinicians in Thailand who are interested in learning new approaches to improve outcomes in Thai breast cancer survivors and cancer care partners. The proposed project is directly responsive to the NOSI that calls for administrative supplements to support NCI-funded investigators to leverage existing relationships/partnerships with stakeholders in LMICs to conduct research that will enhance understanding of the gaps in post-treatment follow-up care, with the goal of addressing physical and psychosocial needs of cancer survivors and their caregivers at the individual, facility, and systems levels. Specifically, this project addresses three priority areas listed in the NOSI including: 1) studies to identify supportive care needs of cancer survivors and their caregivers, 2) research to identify strategies/opportunities for developing health promotion interventions, and 3) feasibility studies to understand adoption and adaption of evidence-based survivorship interventions.

拟议的补充申请响应了在Not-Ca-中确定的特殊利益通知（NOSI） 21-058用于刺激和加强全球癌症生存研究的项目。父母赠款是 效力试验以确定二元运动的好处（例如，患者和配偶在一起）以优化 癌症存活及其配偶护理伙伴之间的身体，情感和关系健康。父母 试验（R01CA218093）着重于患者及其配偶的二元健康，通常是非正式的护理人员，谁 反过来，与不关心爱人的配偶相比，面临不良结果的风险更高。改善健康 诸如体育锻炼之类的行为可以对癌症的生活质量和生存产生重大影响 幸存者及其伴侣，但大多数癌症幸存者的体育锻炼率较低，而健康状况 伙伴几乎被忽略。生活在低至中收入国家（LMIC）的患者面临许多障碍 锻炼，包括缺乏针对癌症患者独特需求的支持性护理计划和缺乏的 社会支持以促进行为改变和维护。我们包括配偶来促进患者 保留和坚持通过社会支持进行锻炼，也可以通过参加运动 配偶本身也可以从变得更加活跃的情况下受益。我们正在提议建立 父母试验机构与Mahidol University与Siriraj医院癌症之间的现有关系 探索二元健康和试点测试概念的中心适应了父母的二元健康状况 促进乳腺癌存活中的体育活动及其配偶护理伙伴的管理策略。 我们将进行两阶段项目，从混合方法开始，以评估二元调整 以及应对乳腺癌的泰国夫妇中的二元健康及其对二元的兴趣和偏好 体育锻炼计划。从第一阶段收集的数据将用于开发和实行特定于文化的数据 泰国夫妇样本中的二元运动计划。拟议的项目将刺激一个新的 父母试验的调查人员与泰国调查人员和临床医生之间的合作 有兴趣学习改善泰国乳腺癌幸存者和癌症护理结果的新方法 合作伙伴。拟议的项目直接响应NOSI，要求进行管理补充 支持由NCI资助的调查人员利用与LMIC中利益相关者的现有关系/伙伴关系 进行研究，以增强对治疗后随访中差距的理解，目的是 满足癌症生存的身体和社会心理需求及其在个人设施中的照顾者 和系统级别。具体而言，该项目涉及NOSI中列出的三个优先领域，包括：1）研究 确定癌症生存的支持性护理需求及其护理人员，2）研究以识别 制定健康促进干预措施的策略/机会，以及3）可行性研究 采用和适应基于证据的生存干预措施。