Expanding Translational Research in Arkansas
Expanding Translational Research in Arkansas
批准号:
10443806
负责人:
Laura P James
金额:
$426.9万
依托单位国家:
美国
项目类别:
财政年份:
2019
资助国家:
美国
项目状态:
已结题
起止时间:
2019-07-01 至 2024-06-30
关键词:
AddressAfrican AmericanAreaArkansasCardiovascular DiseasesClinical ResearchClinical and Translational Science AwardsCollaborationsCommunitiesComplexDeath RateDiabetes MellitusEcosystemEnvironmentFacultyFosteringFoundationsFutureGrowthHealthHealth BenefitHealthcareHealthcare SystemsHomeIndividualInformaticsInstitutionInterdisciplinary StudyInterventionKnowledgeLeadLinkLongevityMeasurableMedicalMethodsMinority GroupsMissionObesityPediatric HospitalsPopulationPositioning AttributePovertyProcessResearchResearch InstituteResearch MethodologyResearch PersonnelResearch SupportResearch TrainingResistanceResourcesRewardsRural MinorityRural PopulationScienceSiteTrainingTranslational ResearchUnderrepresented PopulationsUniversitiesVeteransVisionWorkbasecareercareer developmentcommunity engagementhealth care disparityimprovedinnovationmetropolitannovel strategiesprogramsrural areasuccesstranslational scientist
中文摘要
联系PD/PI:James,Laura P
项目总结
总括
阿肯色州的健康挑战要求阿肯色州医学大学(UAMS)
翻译研究所(TRI)与社区和利益攸关方合作开发和
进行临床和转化研究(CTR),这将显著改善阿肯色州人的健康。作为
翻译研究人员的学术家园,我们的临床和翻译科学奖(CTSA)中心有
开发了高效和足智多谋的工作流程,建立了优秀的研究、培训和教育
计划,并发起了支持团队科学和社区参与发展的倡议。使用
随着我们中心的成熟,我们已经扩大了与我们的参与网站阿肯色州儿童中心的整合
医院(ACH)和阿肯色州中部退伍军人医疗系统(CAVHS)为我们提供
跨这三个紧密联系的多学科研究的不同视角和协作基础-
相互关联的机构。总的来说,UAMS、ACH和CAVHS的中心教员在CTR方面拥有丰富的专业知识
让农村和代表性不足的人口参与进来,并将帮助我们更广泛地扩大CTR资源。我们的
愿景是成为一个蓬勃发展的翻译研究生态系统,将发现催化成健康解决方案
农村人口和代表性不足的人口。在以往成就的基础上,我们今后的工作将是
以以下五个具体目标为指导:目标1)。通过支持和奖励来丰富我们的CTR环境
地方和国家一级的基于团队的协作;目标2)。加强对全球各地研究人员的培训
通过创新和以团队为基础的方法在所有职业水平进行翻译研究;目标
3)。增加与不同利益相关者的合作伙伴关系,以扩大临床和转化性研究的影响
在农村人口中和与农村人口在一起;目标4)。简化翻译研究流程并加强研究
用最先进的信息学途径和方法提高质量;和目标5)。扩展临床和转换
在整个生命周期内和在代表性不足的人群中的研究机会。我们的集体影响
作为CTSA枢纽的成功将为农村和代表性不足的地区有效的CTR提供“现实世界的解决方案”
人口,这是CTSA联盟中代表不足的一个方面。
第303页
项目摘要/摘要
联系PD/PI:James,Laura P
英文摘要
Contact PD/PI: James, Laura P
PROJECT SUMMARY
Overall
The health challenges of Arkansas mandate that the University of Arkansas for Medical Sciences (UAMS)
Translational Research Institute (TRI) works in partnership with communities and stakeholders to develop and
conduct clinical and translational research (CTR) that will measurably improve the health of Arkansans. As the
academic home for translational researchers, our Clinical and Translational Science Award (CTSA) hub has
developed efficient and resourceful workflows, established excellent research training and educational
programs, and launched initiatives to support the growth of team science and community engagement. With
maturation of our hub, we have expanded our integration with our participating sites, Arkansas Children’s
Hospital (ACH) and the Central Arkansas Veteran’s Healthcare System (CAVHS), which provides us with
diverse perspectives and a collaborative foundation of multidisciplinary research across these three closely-
linked institutions. Collectively, hub faculty from UAMS, ACH, and CAVHS have rich expertise in CTR
engaging rural and underrepresented populations and will help us expand CTR resources more broadly. Our
vision is to be a thriving translational research ecosystem that catalyzes discoveries into health solutions for
rural and underrepresented populations. Our future work, based on our previous accomplishments, will be
guided by the following five specific aims: Aim 1). Enrich our environment for CTR by supporting and rewarding
team-based collaborations at the local and national level; Aim 2). Enhance training to researchers across the
translational research spectrum and at all career levels through innovative and team-based approaches; Aim
3). Increase partnerships with diverse stakeholders to expand the impact of clinical and translational research
in and with rural populations; Aim 4). Streamline translational research processes and enhance research
quality with state-of-the-art informatics approaches and methods; and Aim 5). Expand clinical and translational
research opportunities across the lifespan and in underrepresented populations. The collective impact of our
success as a CTSA hub will provide “real world solutions” for effective CTR in rural and underrepresented
populations, a facet insufficiently represented within the CTSA Consortium.
Page 303
Project Summary/Abstract
Contact PD/PI: James, Laura P
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
CTSA Admin Supp2 Maternal Mortality - UL1 - Revision
-
批准号:10200507
-
项目类别:
-
资助金额:$22.8万
-
财政年份:2020
-
负责人:Laura P James
-
依托单位:
CTSA Admin Supp QAQC - UL1 - Revision
-
批准号:10158964
-
项目类别:
-
资助金额:$15.69万
-
财政年份:2019
-
负责人:Laura P James
-
依托单位:
Expanding Translational Research in Arkansas
-
批准号:9893085
-
项目类别:
-
资助金额:$411.31万
-
财政年份:2019
-
负责人:Laura P James
-
依托单位:
Expanding Translational Research in Arkansas
-
批准号:10672218
-
项目类别:
-
资助金额:$426.9万
-
财政年份:2019
-
负责人:Laura P James
-
依托单位:
Expanding Translational Research in Arkansas
-
批准号:10188670
-
项目类别:
-
资助金额:$437.9万
-
财政年份:2019
-
负责人:Laura P James
-
依托单位:
Arkansas ECHO ISPCTN Site (AREIS)
-
批准号:10063720
-
项目类别:
-
资助金额:$42.08万
-
财政年份:2016
-
负责人:Laura P James
-
依托单位:
Arkansas Center for Advancing Pediatric Therapeutics (ArCAPT)
-
批准号:9262528
-
项目类别:
-
资助金额:$6.91万
-
财政年份:2016
-
负责人:Laura P James
-
依托单位:
Dipstick Assay for Detection of Acetaminophen Protein Adducts
-
批准号:8013387
-
项目类别:
-
资助金额:$8.9万
-
财政年份:2010
-
负责人:Laura P James
-
依托单位:
Biomarkers of adverse responses to acetaminophen in children and adolescents
-
批准号:8252206
-
项目类别:
-
资助金额:$37.41万
-
财政年份:2009
-
负责人:Laura P James
-
依托单位:
Identification of new mechanistic biomarkers of adverse responses to acetaminophe
-
批准号:8063985
-
项目类别:
-
资助金额:$37.41万
-
财政年份:2009
-
负责人:Laura P James
-
依托单位:
Identification of new mechanistic biomarkers of adverse responses to acetaminophe
-
批准号:8450902
-
项目类别:
-
资助金额:$32.61万
-
财政年份:2009
-
负责人:Laura P James
-
依托单位:
Identification of new mechanistic biomarkers of adverse responses to acetaminophe
-
批准号:7846097
-
项目类别:
-
资助金额:$40.05万
-
财政年份:2009
-
负责人:Laura P James
-
依托单位:
Identification of new mechanistic biomarkers of adverse responses to acetaminophe
-
批准号:7658559
-
项目类别:
-
资助金额:$47.5万
-
财政年份:2009
-
负责人:Laura P James
-
依托单位:
AcetaSTAT Validation and Commercialization
-
批准号:10481793
-
项目类别:
-
资助金额:$106.97万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
100 Additional fresh samples for verification of assay to replace the original proposed banked samples that cannot be used due to repeated exposure to freezing and thawing.
-
批准号:10837949
-
项目类别:
-
资助金额:$25.38万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
Dipstick Assay for Detection of Acetaminophen Protein Adducts
-
批准号:7591060
-
项目类别:
-
资助金额:$19.98万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
AcetaSTAT Validation and Commercialization
-
批准号:10598625
-
项目类别:
-
资助金额:$106.83万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
Dipstick Assay for Detection of Acetaminophen Protein Adducts
-
批准号:7480828
-
项目类别:
-
资助金额:$19.98万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
Adduct Dipstick for Diagnosis of Acetaminophen Toxicity
-
批准号:8499293
-
项目类别:
-
资助金额:$56.86万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
Adduct Dipstick for Diagnosis of Acetaminophen Toxicity
-
批准号:8303380
-
项目类别:
-
资助金额:$69.88万
-
财政年份:2008
-
负责人:Laura P James
-
依托单位:
海外基金