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Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension

Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
成人高血压患者的睡眠质量和心血管风险机制
批准号：
10443852
负责人：
ANDREW SHERWOOD
金额：
$75.68万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-07-01 至 2024-06-30
来源：
https://reporter.nih.gov/project-details/10443852
关键词：
AddressAdultAmbulatory Blood Pressure MonitoringAntihypertensive AgentsBehavior TherapyBiological AssayBloodBlood PressureCardiovascular DiseasesCatecholaminesCharacteristicsChronic InsomniaCognitive TherapyComorbid InsomniaDoseEventExcretory functionExhibitsFastingHourHypertensionInferiorInterventionInterviewLinkLipidsMeasuresMediatingMeta-AnalysisMonitorMorbidity - disease rateMyocardial InfarctionMyocardial IschemiaOutcome StudyParticipantPatient Self-ReportPatientsPharmaceutical PreparationsPhysiologic pulsePrevalenceReportingResearch DesignRiskRisk FactorsRunningSerumSleepSleep DisordersSleeplessnessStrokeStructureSympathetic Nervous SystemTechnologyVascular EndotheliumWomanWristactigraphyarterial stiffnessbiobehaviorbrachial arterycardiovascular disorder riskcardiovascular risk factorcircadiandesignfallsfollow-upimprovedmenmortalitymultimodalitypoor sleepsleep qualitytreatment responseurinary

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中文摘要
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英文摘要
R01 Brief Project Summary Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension The objective of the study is to elucidate the potential mechanisms responsible for the increased risk of CVD among patients with hypertension and comorbid insomnia. To address this issue, we propose to utilize a behavioral intervention to manipulate sleep quality in 150 adults with hypertension and comorbid insomnia, who will receive a 6-week Cognitive Behavioral Therapy for Insomnia (CBT-I) intervention, which has been shown to markedly improve sleep quality and promote consolidated sleep in approximately 60% of those treated. Blunted nighttime blood pressure dipping is one of several proposed mechanisms to be examined.
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Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
  • 批准号：
    10651685
  • 项目类别：
  • 资助金额：
    $74.09万
  • 财政年份：
    2019
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
  • 批准号：
    10246161
  • 项目类别：
  • 资助金额：
    $75.8万
  • 财政年份：
    2019
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Depression and Heart Failure Disease Progression
  • 批准号：
    8761047
  • 项目类别：
  • 资助金额：
    $74.67万
  • 财政年份：
    2014
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Depression and Heart Failure Disease Progression
  • 批准号：
    9095471
  • 项目类别：
  • 资助金额：
    $85.35万
  • 财政年份：
    2014
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
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