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Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension

Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
成人高血压患者的睡眠质量和心血管风险机制
批准号：
10651685
负责人：
ANDREW SHERWOOD
金额：
$74.09万
依托单位：
DUKE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
项目状态：
已结题
起止时间：
2019-07-01 至 2024-06-30
来源：
https://reporter.nih.gov/project-details/10651685
关键词：
AddressAdultAmbulatory Blood Pressure MonitoringAntihypertensive AgentsBehavior TherapyBiological AssayBloodBlood PressureCardiovascular DiseasesCatecholaminesCharacteristicsChronic InsomniaCognitive TherapyComorbid InsomniaDoseEventExcretory functionExhibitsFastingHourHypertensionInferiorInterventionInterviewLinkLipidsMeasuresMediatingMeta-AnalysisMorbidity - disease rateMyocardial InfarctionMyocardial IschemiaOutcome StudyParticipantPatient Self-ReportPatientsPharmaceutical PreparationsPhysiologic pulsePrevalenceReportingResearch DesignRisk FactorsRisk ReductionRunningSerumSleepSleep DisordersSleeplessnessStrokeStructureSympathetic Nervous SystemTechnologyVascular EndotheliumWomanWristactigraphyarterial stiffnessbiobehaviorbrachial arterycandidate identificationcardiovascular disorder riskcardiovascular risk factorcircadiandesignfallsfollow-upimprovedimprovement on sleepmenmortalitymultimodalitypoor sleeprisk predictionsleep qualitytreatment responseurinary

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中文摘要
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英文摘要
R01 Brief Project Summary Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension The objective of the study is to elucidate the potential mechanisms responsible for the increased risk of CVD among patients with hypertension and comorbid insomnia. To address this issue, we propose to utilize a behavioral intervention to manipulate sleep quality in 150 adults with hypertension and comorbid insomnia, who will receive a 6-week Cognitive Behavioral Therapy for Insomnia (CBT-I) intervention, which has been shown to markedly improve sleep quality and promote consolidated sleep in approximately 60% of those treated. Blunted nighttime blood pressure dipping is one of several proposed mechanisms to be examined.
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会议论文
Cognitive behavior therapy for insomnia for untreated hypertension with comorbid insomnia disorder: The SLEEPRIGHT clinical trial.
针对未治疗的高血压合并失眠症的失眠症的认知行为疗法：SLEEPRIGHT 临床试验。
DOI： 10.1111/jch.14763
发表时间： 2024
期刊： Journal of clinical hypertension (Greenwich, Conn.)
影响因子： --
作者： [Sherwood,Andrew, Ulmer,Christi, Wu,JadeQ, Blumenthal,JamesA, Herold,Emma, Smith,PatrickJ, Koch,GaryG, Johnson,Kristy, Viera,Anthony, Edinger,Jack, Hinderliter,Alan]
通讯作者： Hinderliter,Alan
Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
  • 批准号：
    10443852
  • 项目类别：
  • 资助金额：
    $75.68万
  • 财政年份：
    2019
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Sleep Quality and Mechanisms of Cardiovascular Risk in Adults with Hypertension
  • 批准号：
    10246161
  • 项目类别：
  • 资助金额：
    $75.8万
  • 财政年份：
    2019
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Depression and Heart Failure Disease Progression
  • 批准号：
    8761047
  • 项目类别：
  • 资助金额：
    $74.67万
  • 财政年份：
    2014
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
Depression and Heart Failure Disease Progression
  • 批准号：
    9095471
  • 项目类别：
  • 资助金额：
    $85.35万
  • 财政年份：
    2014
  • 负责人：
    ANDREW SHERWOOD
  • 依托单位：
    DUKE UNIVERSITY
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