Emory-CDC CTU

埃默里大学CDC CTU

• 批准号: 10305624
• 负责人: Jeffrey Lennox
• 金额: $ 316.6万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2027-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10305624
• 关键词: AIDS prevention; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Americas; Anti-Retroviral Agents; Area; Biological Products; Centers for Disease Control and Prevention (U.S.); Childhood; Cities; Clinic; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical Trials Unit; Collaborations; Complex; Conduct Clinical Trials; Country; Development; Disease; Disease remission; Enrollment; Epidemic; Funding; Grant; HIV; HIV Infections; HIV therapy; HIV vaccine; HIV/TB; Hepatitis; Infection; Inflammation; Institution; International; Intervention; Kenya; Latino; Malignant Neoplasms; Methods; Mexico; Minority; Mission; National Institute of Allergy and Infectious Disease; Network Infrastructure; Opportunistic Infections; Organ; Pharmaceutical Preparations; Philippines; Population; Population Heterogeneity; Positioning Attribute; Prevention; Prevention strategy; Primates; Protocols documentation; Public Policy; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Research Subjects; Scientific Advances and Accomplishments; Site; Social Behavior; Strategic Planning; Technology; Thailand; Therapeutic; Translating; Translational Research; Tuberculosis; Tuberculosis Vaccines; Underrepresented Populations; United States National Institutes of Health; Universities; Vaccines; Woman; Youth; base; clinical center; clinical implementation; clinical research site; co-infection; comorbidity; experience; flexibility; high risk; human subject; improved; low and middle-income countries; member; men; next generation; novel; prevent; programs; recruit; success; support network; therapeutic vaccine; treatment strategy; tuberculosis treatment; vaccine development; volunteer; working group

Project Summary/Abstract The currently funded Emory-CDC Clinical Trials Unit (Emory-CDC CTU) is ideally positioned to implement the mission of NIAID and to conduct clinical trials developed by the NIH HIV/AIDS Clinical Trials Networks. The Emory-CDC CTU is supported by Emory’s rich scientific milieu with numerous synergistic grants and various thematic research centers covering all network priority areas, as well as the support and experience of our CDC partners. The Emory-CDC CTU is comprised of 5 CRSs with well-established programs and histories of performing NIH funded clinical research. In this renewal the Emory-CDC CTU will be expanding to a 6th CRS in Mexico City. Our specific aims are the following: 1. To contribute scientific expertise and human subject enrollment into studies that address these four key research areas: Adult HIV therapeutic strategies, including HIV cure, noninfectious comorbidities, and the infectious comorbidities of hepatitis and tuberculosis; strategies to address HIV and HIV-associated infections in pediatric and maternal populations; integrated HIV prevention strategies; and vaccines to prevent HIV infection. 2. To be a leading CTU for contributions of women, minorities, and adolescents to support network clinical trials, both domestically and in low and middle-income countries. 3. To operate an efficient and flexible CTU that can respond rapidly to evolving research opportunities. 4. To participate in the development and implementation of the clinical research plans of all the NIAID clinical research networks that are addressing the four priority areas.

项目摘要/摘要 目前资助的埃默里-疾控中心临床试验单位(埃默里-疾控中心CTU)非常适合 履行……的使命 NIAID并进行由NIH艾滋病毒/艾滋病研究所开发的临床试验 临床试验网络。 埃默里-CDC CTU得到了埃默里丰富的科学环境的支持 拥有众多的协同拨款和覆盖所有网络的各种主题研究中心 优先领域，以及我们疾控中心合作伙伴的支持和经验。埃默里-疾控中心 CTU由5名CRSS组成，他们拥有完善的计划和执行NIH的历史 资助临床研究。在这次更新中，Emory-CDC CTU将在#年扩展到第6个CRS 墨西哥城。我们的具体目标如下： 1.为解决以下问题的研究贡献科学专长和人类学科招生 这四个关键研究领域：成人艾滋病毒治疗战略，包括艾滋病毒治疗， 非传染性并存，以及肝炎和肝炎的传染性并存 结核病；在儿童和青少年中处理艾滋病毒和艾滋病毒相关感染的战略 孕产妇人口；艾滋病毒综合预防战略；预防艾滋病毒的疫苗 感染。 2.成为妇女、少数群体和青少年支持的主要CTU 在国内以及在低收入和中等收入国家开展临床试验网络。 3.运营高效灵活的CTU，能够对不断发展的研究做出快速反应 机遇。 4.参与制定和实施各国的临床研究计划 NIAID临床研究网络正在处理四个优先领域。