Emory-CDC CTU

埃默里大学CDC CTU

• 批准号: 10057691
• 负责人: Jeffrey Lennox
• 金额: $ 313.48万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2027-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10057691
• 关键词: AIDS prevention; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Americas; Anti-Retroviral Agents; Area; Biological; Centers for Disease Control and Prevention (U.S.); Childhood; Cities; Clinic; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical Trials Unit; Collaborations; Complex; Conduct Clinical Trials; Country; Development; Disease; Disease remission; Enrollment; Epidemic; Funding; Grant; HIV; HIV Infections; HIV therapy; HIV vaccine; HIV/TB; Hepatitis; Infection; Inflammation; Institution; International; Intervention; Kenya; Latino; Malignant Neoplasms; Methods; Mexico; Minority; Mission; National Institute of Allergy and Infectious Disease; Network Infrastructure; Opportunistic Infections; Organ; Pharmaceutical Preparations; Philippines; Population; Population Heterogeneity; Positioning Attribute; Prevention; Prevention strategy; Primates; Protocols documentation; Public Policy; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Research Subjects; Scientific Advances and Accomplishments; Site; Social Behavior; Strategic Planning; Technology; Thailand; Therapeutic; Translating; Translational Research; Tuberculosis; Tuberculosis Vaccines; Underrepresented Populations; United States National Institutes of Health; Universities; Vaccines; Woman; Youth; base; clinical center; clinical implementation; clinical research site; co-infection; comorbidity; experience; flexibility; high risk; human subject; improved; low and middle-income countries; member; men; next generation; novel; prevent; programs; recruit; success; support network; therapeutic vaccine; treatment strategy; tuberculosis treatment; vaccine development; volunteer; working group

Project Summary/Abstract The currently funded Emory-CDC Clinical Trials Unit (Emory-CDC CTU) is ideally positioned to implement the mission of NIAID and to conduct clinical trials developed by the NIH HIV/AIDS Clinical Trials Networks. The Emory-CDC CTU is supported by Emory’s rich scientific milieu with numerous synergistic grants and various thematic research centers covering all network priority areas, as well as the support and experience of our CDC partners. The Emory-CDC CTU is comprised of 5 CRSs with well-established programs and histories of performing NIH funded clinical research. In this renewal the Emory-CDC CTU will be expanding to a 6th CRS in Mexico City. Our specific aims are the following: 1. To contribute scientific expertise and human subject enrollment into studies that address these four key research areas: Adult HIV therapeutic strategies, including HIV cure, noninfectious comorbidities, and the infectious comorbidities of hepatitis and tuberculosis; strategies to address HIV and HIV-associated infections in pediatric and maternal populations; integrated HIV prevention strategies; and vaccines to prevent HIV infection. 2. To be a leading CTU for contributions of women, minorities, and adolescents to support network clinical trials, both domestically and in low and middle-income countries. 3. To operate an efficient and flexible CTU that can respond rapidly to evolving research opportunities. 4. To participate in the development and implementation of the clinical research plans of all the NIAID clinical research networks that are addressing the four priority areas.

项目概要/摘要 目前资助的埃默里-CDC 临床试验单位 (Emory-CDC CTU) 非常适合 履行使命 NIAID 并进行 NIH HIV/AIDS 开发的临床试验 临床试验网络。 Emory-CDC CTU 得到了埃默里丰富的科学环境的支持 拥有众多协同赠款和覆盖所有网络的各种主题研究中心 优先领域，以及我们的 CDC 合作伙伴的支持和经验。埃默里大学疾病预防控制中心 CTU 由 5 个 CRS 组成，拥有完善的项目和执行 NIH 的历史 资助临床研究。在这次更新中，埃默里-CDC CTU 将扩展到第 6 个 CRS 墨西哥城。我们的具体目标如下： 1. 为解决以下问题的研究贡献科学专业知识和人类受试者登记 这四个关键研究领域： 成人艾滋病毒治疗策略，包括艾滋病毒治愈， 非感染性合并症以及肝炎和肝炎等感染性合并症 结核;解决儿科和艾滋病毒相关感染的策略 产妇人口；综合艾滋病毒预防战略；和预防艾滋病毒的疫苗 感染。 2. 成为为妇女、少数族裔和青少年做出贡献的领先 CTU，以支持 国内和低收入和中等收入国家的网络临床试验。 3. 运营一个高效、灵活的 CTU，能够快速响应不断发展的研究 机会。 4. 参与各临床研究计划的制定和实施 NIAID 临床研究网络正在解决四个优先领域。