Emory-CDC CTU

埃默里大学CDC CTU

• 批准号: 10057691
• 负责人: Jeffrey Lennox
• 金额: $ 313.48万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-02-01 至 2027-11-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10057691
• 关键词: AIDS prevention; AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Adolescent; Adult; Americas; Anti-Retroviral Agents; Area; Biological; Centers for Disease Control and Prevention (U.S.); Childhood; Cities; Clinic; Clinical Research; Clinical Trials; Clinical Trials Network; Clinical Trials Unit; Collaborations; Complex; Conduct Clinical Trials; Country; Development; Disease; Disease remission; Enrollment; Epidemic; Funding; Grant; HIV; HIV Infections; HIV therapy; HIV vaccine; HIV/TB; Hepatitis; Infection; Inflammation; Institution; International; Intervention; Kenya; Latino; Malignant Neoplasms; Methods; Mexico; Minority; Mission; National Institute of Allergy and Infectious Disease; Network Infrastructure; Opportunistic Infections; Organ; Pharmaceutical Preparations; Philippines; Population; Population Heterogeneity; Positioning Attribute; Prevention; Prevention strategy; Primates; Protocols documentation; Public Policy; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Research Subjects; Scientific Advances and Accomplishments; Site; Social Behavior; Strategic Planning; Technology; Thailand; Therapeutic; Translating; Translational Research; Tuberculosis; Tuberculosis Vaccines; Underrepresented Populations; United States National Institutes of Health; Universities; Vaccines; Woman; Youth; base; clinical center; clinical implementation; clinical research site; co-infection; comorbidity; experience; flexibility; high risk; human subject; improved; low and middle-income countries; member; men; next generation; novel; prevent; programs; recruit; success; support network; therapeutic vaccine; treatment strategy; tuberculosis treatment; vaccine development; volunteer; working group

Project Summary/Abstract The currently funded Emory-CDC Clinical Trials Unit (Emory-CDC CTU) is ideally positioned to implement the mission of NIAID and to conduct clinical trials developed by the NIH HIV/AIDS Clinical Trials Networks. The Emory-CDC CTU is supported by Emory’s rich scientific milieu with numerous synergistic grants and various thematic research centers covering all network priority areas, as well as the support and experience of our CDC partners. The Emory-CDC CTU is comprised of 5 CRSs with well-established programs and histories of performing NIH funded clinical research. In this renewal the Emory-CDC CTU will be expanding to a 6th CRS in Mexico City. Our specific aims are the following: 1. To contribute scientific expertise and human subject enrollment into studies that address these four key research areas: Adult HIV therapeutic strategies, including HIV cure, noninfectious comorbidities, and the infectious comorbidities of hepatitis and tuberculosis; strategies to address HIV and HIV-associated infections in pediatric and maternal populations; integrated HIV prevention strategies; and vaccines to prevent HIV infection. 2. To be a leading CTU for contributions of women, minorities, and adolescents to support network clinical trials, both domestically and in low and middle-income countries. 3. To operate an efficient and flexible CTU that can respond rapidly to evolving research opportunities. 4. To participate in the development and implementation of the clinical research plans of all the NIAID clinical research networks that are addressing the four priority areas.

项目总结/摘要 目前资助的Emory-CDC临床试验单位（Emory-CDC CTU）的理想定位是 履行.的使命 NIAID并进行由NIH HIV/AIDS开发的临床试验 临床试验网络。 埃默里-疾控中心反恐组得到了埃默里丰富的科学环境的支持 与众多的协同赠款和各种专题研究中心覆盖所有网络 优先领域，以及我们的CDC合作伙伴的支持和经验。Emory-CDC CTU由5个CRS组成，这些CRS具有完善的计划和执行NIH的历史 资助的临床研究。在这次更新中，Emory-CDC CTU将在2015年扩展到第六个CRS。 墨西哥城我们的具体目标如下： 1.为研究贡献科学专业知识和人类受试者入组， 这四个关键研究领域：成人艾滋病毒治疗策略，包括艾滋病毒治愈， 非感染性合并症，以及肝炎和 结核病;解决儿科和儿科艾滋病毒和艾滋病毒相关感染的策略 孕产妇人口;艾滋病毒综合预防战略;预防艾滋病毒的疫苗 感染 2.成为领导CTU的女性，少数民族和青少年的贡献，以支持 在国内和中低收入国家开展网络临床试验。 3.运营一个高效灵活的CTU，能够快速响应不断发展的研究 机会 4.参与所有临床研究计划的制定和实施 NIAID临床研究网络正在解决四个优先领域。