In-the-kNOW (Novel approaches to Optimizing Women’s Health): A mobile application to optimize HIV prevention and sexual/reproductive health communication among Black women in the Southern U.S.

In-the-kNOW（优化女性健康的新方法）：一款优化美国南部黑人女性艾滋病毒预防和性/生殖健康沟通的移动应用程序。

• 批准号: 10328020
• 负责人: Rasheeta Chandler
• 金额: $ 24.81万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10328020
• 关键词: AIDS prevention; Accounting; Address; Age; Area; Behavior; COVID-19; COVID-19 pandemic; Caring; Centers for Disease Control and Prevention (U.S.); Child; Collaborations; Communication; Communication Research; Communities; County; Development; Diagnosis; Early Diagnosis; Effectiveness; Epidemic; Face; Feedback; HIV; HIV Infections; HIV diagnosis; HIV risk; HIV/STD; Health Promotion; Health Services Research; High Risk Woman; Hispanics; Human; Human immunodeficiency virus test; Infection; Infrastructure; Intervention; Letters; Link; Monitor; Outcome Measure; Participant; Performance; Population; Prevalence; Prevention; Preventive; Reporting; Reproductive Health; Research; Research Priority; Resources; Risk Reduction; Sampling; Scientist; Secure; Self Care; Services; Sexual Health; Technology; Testing; Time; Woman; Women' s Health; acceptability and feasibility; arm; base; black women; care seeking; cis-female; cisgender; combat; community based participatory research; design; effectiveness evaluation; evidence base; group intervention; health communication; intervention refinement; medication compliance; men who have sex with men; mobile application; mobile computing; novel strategies; portability; pre-exposure prophylaxis; prevent; prevention service; response; retention rate; satisfaction; scale up; secondary outcome; social cognitive theory; social stigma; tertiary prevention; testing services; theories; tool; uptake; usability

Black women have the second highest rate of all new HIV infections in the U.S. after men who have sex with men, and they account for 69% of all HIV diagnoses among women in the South (e.g., Georgia). The objective of the proposed research is to refine and test in-the-kNOW (Novel approaches to Optimizing Women's Health), an evidence-based and theory-driven mobile application (app) specifically designed for PrEP-eligible Black women. This app responds to RFA-MH-21-150 Health Communication and Services Research priorities by incorporating portable, culturally- and contextually-relevant messaging strategies. Our definition of PrEP-eligible is based on CDC guidance for Black women, namely women who live in high HIV prevalence areas (specifically Ending the HIV Epidemic jurisdictions in Georgia: Fulton, Dekalb, Gwinnett, or Cobb counties). In our preliminary study, participants endorsed our mobile app intervention, in-the-kNOW, and expressed a desire for a fully developed and integrated version. Guided by Community-based Participatory Research (CBPR) principles and the Social Cognitive Theory of Mass Communication (SCT-MC), we will address the PrEP health communication gap with the in-the-Know app, which offers personalized messaging to promote HIV preventive behaviors among Black women in the South. We hypothesize that the in-the-kNOW intervention and the control condition (e.g. referral to the CDC's online HIV risk reduction tools) will be feasible to Black women. In a sample of PrEP-eligible Black women (ages 18-44), we propose the following aims: Aim 1. Refine the in-the-kNOW mobile app for PrEP-eligible Black women. Using a human-centered design approach 27, we will conduct a single-arm technology usability pretest to optimize usability, technical functionality, and performance of the app, among n = 10 PrEP-eligible Black women. The mobile app will be refined per pretest feedback. Aim 2a. Evaluate the feasibility, acceptability, and usability of the refined in-the-kNOW mobile app. We will employ experimental (n = 20) and control (n = 20) conditions to determine the feasibility and acceptability (retention rates and satisfaction) of both the app and the control condition (e.g., referral to the CDC's online HIV risk reduction tools). Aim 2b. Determine feasibility of collecting secondary outcome measures (e.g. PrEP Stigma) for a R01.

黑人妇女在美国所有新的艾滋病毒感染率中排名第二，仅次于男男性行为者，她们占南方妇女所有艾滋病毒诊断的69%（例如，格鲁吉亚）。拟议的研究的目的是完善和测试的知识（新颖的方法来优化妇女的健康），一个基于证据和理论驱动的移动的应用程序（应用程序）专门为准备合格的黑人妇女设计。该应用程序响应RFA-MH-21-150健康传播和服务研究的优先事项，结合便携式，文化和上下文相关的消息传递策略。我们对符合PrEP条件的定义是基于CDC对黑人妇女的指导，即生活在艾滋病毒高流行地区的妇女（特别是结束格鲁吉亚的艾滋病毒流行管辖区：富尔顿，Dekalb，Gwinnett或Cobb县）。在我们的初步研究中，参与者赞同我们的移动的应用程序干预，在知道，并表达了一个完整的开发和集成版本的愿望。以社区为基础的前瞻性研究（CBPR）原则和大众传播的社会认知理论（SCT-MC）为指导，我们将通过知情应用程序解决PrEP健康沟通差距，该应用程序提供个性化消息，以促进南方黑人妇女的艾滋病毒预防行为。我们假设，在知道的干预和控制条件（如转诊到疾病预防控制中心的在线艾滋病毒风险降低工具）将是可行的黑人妇女。在符合PrEP条件的黑人妇女（年龄18-44）的样本中，我们提出了以下目标：目标1.为符合PrEP条件的黑人女性完善知情的移动的应用程序。使用以人为本的设计方法27，我们将在n = 10名符合PrEP条件的黑人女性中进行单臂技术可用性预测试，以优化应用程序的可用性、技术功能和性能。将根据预测试反馈完善移动的应用程序。目标2a。评估改进的已知移动的应用程序的可行性、可接受性和可用性。我们将采用实验（n = 20）和对照（n = 20）条件来确定应用程序和对照条件（例如，转介到CDC的在线艾滋病毒风险降低工具）。目标2b。确定收集R 01次要结局指标（例如PrEP污名）的可行性。