Cooperative Research Center for NanoScaffold-Based Chlamydia trachomatis Vaccines - Admin Core

基于纳米支架的沙眼衣原体疫苗合作研究中心 - 管理核心

• 批准号: 10458650
• 负责人: Matthew Adrian Coleman
• 金额: $ 28.61万
• 依托单位: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-08 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10458650
• 关键词: Address; Advisory Committees; Affect; Area; Award; Blindness; Budgets; California; Chlamydia trachomatis; Communication; Data; Development; Discipline; Ectopic Pregnancy; Ensure; Funding; Goals; Grant; Health; Infection; Infertility; Institutes; Laboratories; Leadership; Monitor; National Institute of Allergy and Infectious Disease; Pathogenesis; Pelvic Inflammatory Disease; Persons; Progress Reports; Research; Research Personnel; Research Project Grants; Scientist; Sexually Transmitted Diseases; Site; Supervision; Talents; Technology; Training; United States; United States National Institutes of Health; Universities; Vaccines; Work; base; chronic abdominal pain; cost; data sharing; long-term sequelae; meetings; member; nano; new technology; novel vaccines; outreach; pathogenic bacteria; programs; recruit; research and development; scaffold; web site

PROJECT SUMMARY/ABSTRACT Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted infection (STI), affecting over 130 million people every year, and is the most common cause of preventable blindness worldwide. In the United States, STIs caused by C. trachomatis account for billions of dollars in annual costs. Because the infection can be asymptomatic, it may go untreated for years and can result in long-term sequelae, including pelvic inflammatory disease, chronic abdominal pain, ectopic pregnancy, and infertility. Ct is an intracellular bacterial pathogen widespread throughout the world. In order to address the critical need for a C. trachomatis vaccine, the Administrative Core will be responsible for managing, coordinating, monitoring overall progress, and supervising the entire range of the center's activities, including the Developmental Research Program (DRP). This will involve coordination of work between three primary sites: LLNL, UCI and UCD with an emphasis on developing young scientist and novel technologies to mitigate health effects associated with C. trachomatis. The Core will focus on the following four areas: 1) Provide coordination to facilitate interactions among the CRC Project PIs and Core Directors. 2) To ensure internal data sharing and an external site for scientific outreach. 3) Establish and administrate the Developmental Research Program. 4) Evaluate the Center's progress utilizing internal and external advisory reviews.

项目总结/文摘