National Capital Area (NCA) Minority/Underserved NCORP

摘要 国家首都地区(NCA)少数民族/服务不足的NCORP将驻扎在乔治敦隆巴迪 综合癌症中心(LCCC)，由Medstar乔治敦大学医院(MGUH)和 MedStar华盛顿医院中心(MWHC)为主要附属机构，集水区占48.3% 非拉美裔黑人(NLB)和10.6%的拉美裔/拉丁裔(H/L)，包括华盛顿特区和邻近地区 马里兰州和弗吉尼亚州的县。MWHC主要为少数人服务，即85%的人服务不足 治疗2,000多名以少数族裔为主的癌症患者和48,000名门诊患者， 每年一次。在集水区的新落叶松人口中，癌症负担和差异最大，因为 乳腺癌、前列腺癌和结直肠癌的死亡率在全国名列前茅。其中 H/L人群中，癌症是主要的死亡原因，H/L患者通常出现在晚期 与非拉丁裔白人(NLW)患者相比。肥胖等可预防癌症风险因素的高比率， 缺乏体力活动和吸烟，再加上对某些癌症的筛查率要低得多，例如结直肠癌 少数族裔的宫颈癌造成了集水区的癌症差异。NCA NCORP建议解决与这些癌症差异相关的最重要的因素之一--有限 通过提高认识，获得最佳和尖端的预防、癌症控制和癌症护理服务 并在集水区提供在NLB和H/L之间进行癌症临床试验的机会。LCCC办公室 少数群体健康和健康差距研究(OMH)代表由以下人员领导的社区外展机构 亚当斯-坎贝尔博士，已经建立了可行的学术和社区伙伴关系，使NCA NCORP将在预防、控制、筛查、健康差距和癌症等领域进行临床研究 在关注的少数群体中提供护理服务。鉴于人口老龄化和人口数量的不断增加 在癌症幸存者中，NCORP拥有专业知识和领导能力，这一点从以下方面的研究中得到了证明 解决癌症控制和以患者为中心的癌症护理服务的领域。此外，解决问题的能力 青少年和青壮年癌症防治(AYA)也是我们团队的一项关键优势。 NCA NCORP将通过癌症预防、控制和筛查来满足我们集水区的需求 作为治疗和影像研究。拟议的国家首都地区NCORP的具体目标是：(1) 设计和参与癌症临床研究的临床试验，以提高护理质量和健康 美国人口在我们的集水区的成果；(2)增加大华盛顿地区的参与 参加NCORP领导的临床研究的社区肿瘤学家和医学专家及其患者；以及 通过社区推广扩大以临床研究参与为重点的健康差距研究， 参与度和教育。

Abstract The National Capital Area (NCA) Minority/Underserved NCORP will be based at Georgetown Lombardi Comprehensive Cancer Center (LCCC), comprising Medstar Georgetown University Hospital (MGUH) and MedStar Washington Hospital Center (MWHC) as the primary affiliate, with a catchment area comprising 48.3% non-Latino Blacks (NLB) and 10.6% Hispanics/Latinos (H/L) that includes Washington, D.C. and adjacent counties in Maryland and Virginia. MWHC serves predominantly, i.e., > 85% minority and underserved populations; and treats more than 2,000 predominantly minority cancer patients and 48,000 outpatients, annually. The cancer burden and disparities are greatest among NLB population in the catchment area as evident by some of the highest mortality rates in the nation for breast, prostate, and colorectal cancers. Among the H/L population, cancer is the leading cause of death with H/L patients typically presenting at a later stage compared to Non-Latino White (NLW) patients. High rates of preventable cancer risk factors such as obesity, physical inactivity, and smoking, coupled with much lower screening rates for certain cancers, such as colorectal and cervical cancers in minorities contribute to the cancer disparities seen in the catchment area. The NCA NCORP proposes to address one of the most significant factors associated with these cancer disparities - limited access to optimal and cutting edge prevention, cancer control, and cancer care delivery by increasing awareness and providing access to cancer clinical trials among NLB and H/L in the catchment area. LCCC’s Office of Minority Health and Health Disparities Research (OMH), represents the community outreach arm that is led by Dr. Adams-Campbell, that has established viable academic-community partnerships that enable the NCA NCORP to conduct clinical research in areas of prevention, control, screening, health disparities, and cancer care delivery among the minority populations of interest. In light of an aging population and the increasing number of cancer survivors, this NCORP has the expertise and leadership as evident by demonstrable research in these areas that address cancer control and patient centered cancer care delivery. Furthermore, the ability to address cancer prevention and control among adolescents and young adults (AYA) is also a key strength of our team. The NCA NCORP will address the needs of our catchment area via cancer prevention, control, screening as well as treatment and imaging studies. The specific aims of the proposed National Capital Area NCORP are to: (1) Design and participate in clinical trials in cancer clinical research that improves the quality of care and the health outcomes of the US population in our catchment area; (2) Increase the participation of the greater DC area’s community oncologists and medical specialists and their patients in NCORP-led clinical research; and (3) Expand health disparities research focused on clinical research participation via community outreach, engagement, and education.