Interrupting the Intergenerational Transmission of Traumatic Stress: Identifying Parental Targets for Intervention by Looking Under the Skin

中断创伤性应激的代际传递：通过深入观察确定父母的干预目标

• 批准号: 10458617
• 负责人: Nastassia Josephine Hajal
• 金额: $ 18.94万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10458617
• 关键词: 6 year old; Address; Adult; Alexithymias; Anger; Arousal; Awareness; Basic Science; Behavior; Behavioral; Biological Markers; Brain; Child; Child Behavior; Child Development; Child Rearing; Child Support; Childhood; Clinical Research; Clinical Trials; Cognitive; Control Groups; Coping Skills; Data; Depressed mood; Distress; Effectiveness; Electrodes; Electroencephalography; Emotional; Emotions; Empathy; Evidence based intervention; Exhibits; Family; Fathers; Foundations; Fright; Goals; Impairment; Individual; Interruption; Intervention; K-Series Research Career Programs; Knowledge; Left; Literature; Manuscripts; Measures; Mental Health; Mental Health Services; Mentorship; Methodology; Methods; Modeling; Mothers; Motivation; Numbness; Nursery Schools; Parent-Child Relations; Parents; Parietal; Parietal Lobe; Patient Self-Report; Pattern; Phase; Play; Population; Problem behavior; Process; Psychopathology; Psychophysiology; Publications; Regulation; Reporting; Research; Research Methodology; Research Training; Resolution; Risk; Role; Sampling; Scientist; Services; Skin; Stimulus; Structure; Symptoms; Testing; Training; Translational Research; Trauma; Withdrawal; Work; Writing; aged; associated symptom; base; biobehavior; career; coping; design; emotion dysregulation; emotion regulation; emotional symptom; evidence base; executive function; experience; frontal lobe; group intervention; improved; indexing; intergenerational; interpersonal trauma; intervention program; irritation; millisecond; neural correlate; neurophysiology; novel; post-traumatic symptoms; prevent; resilience; response; skills; source localization; stress related disorder; temporal measurement; therapy design; transmission process; trauma exposure; traumatic stress; treatment guidelines; treatment response; virtual

PROJECT SUMMARY/ABSTRACT Parental psychopathology, including traumatic stress, presents significant risk to children’s development and to their ability to benefit from evidence-based mental health services when needed. Child interventions require parents to have specific and controlled responses to child distress and challenging behaviors, yet these are the very moments that evoke negative emotions in parents. The emotional dysregulation that underlies traumatic stress and related disorders may account for this hindrance in child development and response-to-treatment, and thus, more refined work on parent emotion regulation (ER) is sorely needed. The proposed research and training will focus on enhancing the field’s knowledge of emotional processes and response-to-intervention in parents who have experienced trauma. This is a particularly important population in which to study parental ER, as the emotional symptoms of traumatic stress are diverse, ranging from anger to horror to emotional numbing, and often arise unexpectedly. The proposed research will use neurophysiological assessment (EEG) to elucidate emotional arousal, motivation, and regulatory processes in N = 60 parents who experienced interpersonal trauma during their own childhoods, and who currently have preschool-aged children (3- to 6-year-olds). The project design will include a clinical trial and use of EEG biomarkers to measure response to a trauma-informed parenting intervention program. In order to conduct the proposed research and to prepare the candidate for the next phase of her career as an independent scientist, the proposed training provides guidance from an exceptional mentorship team in the following goals: (1) enhance depth of knowledge and conceptualization of emotion, parenting, and traumatic stress by applying biobehavioral and process-oriented, dyadic models to this work (2) expand depth and breadth of knowledge and skills in psychophysiological methods, (3) develop the ability to conduct independent research in the applied stages of translational science, (4) augment methodological and statistical skills, and (5) increase opportunities for and skills in manuscript-writing and publication. The proposed training will support the candidate’s long-term career goal to conduct translational work that integrates novel, basic research on parental emotional processes with applied work on child and family resilience, with the ultimate goal of preventing the intergenerational transmission of traumatic stress.

项目总结/摘要 父母的精神病理学，包括创伤性应激反应，对儿童的健康有重大风险。 发展和他们在需要时从循证精神卫生服务中受益的能力。孩子 干预措施要求父母对儿童的痛苦和挑战有具体和有控制的反应， 行为，但这些正是引起父母负面情绪的时刻。的情感 造成创伤性压力和相关疾病的失调可能是造成儿童这种障碍的原因。 发展和对治疗的反应，因此，对父母情绪调节（ER）的更精细的工作是 非常需要。 拟议的研究和培训将侧重于提高该领域的情感知识， 过程和应对干预经历过创伤的父母。这是一个特别 研究父母ER的重要人群，因为创伤应激的情绪症状多种多样， 从愤怒到恐惧，再到情感麻木，而且往往会出乎意料地出现。拟议的研究将 使用神经生理学评估（EEG）来阐明情绪唤醒，动机和调节 在N = 60名在自己的童年经历过人际创伤的父母中， 目前有学龄前儿童（3至6岁）。项目设计将包括临床试验， 使用EEG生物标志物来测量对创伤知情的父母干预计划的反应。 为了进行拟议的研究，并准备候选人的下一阶段，她 职业生涯作为一个独立的科学家，拟议的培训提供指导，从一个特殊的导师 团队在以下目标：（1）提高知识的深度和概念化的情感，养育， 创伤压力，通过应用生物行为和过程导向，二元模型，这项工作（2）扩大深度 心理生理学方法的知识和技能的广度，（3）发展进行 翻译科学应用阶段的独立研究，（4）增加方法和统计 技能，和（5）增加的机会和技能，在论文写作和出版。 建议的培训将支持候选人的长期职业目标，进行翻译工作 它将对父母情感过程的新颖的基础研究与对儿童和家庭的应用研究相结合， 复原力，最终目标是防止创伤性压力的代际传递。