Administrative Core

行政核心

• 批准号: 10455076
• 负责人: KELLY L DREW
• 金额: $ 148.44万
• 依托单位: UNIVERSITY OF ALASKA FAIRBANKS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10455076
• 关键词: Adopted; Advisory Committees; Aging; Alaska; Arctic Regions; Arts; Basic Science; Bioinformatics; Biological Sciences; Biology; Biomedical Research; Biometry; Centers of Research Excellence; Clinical; Coke; Collaborations; Committee Members; Complex; Core Facility; Development; Development Plans; Doctor of Philosophy; Educational workshop; Ensure; Environment; Essential Amino Acids; Evaluation; Experimental Designs; Extramural Activities; Faculty; Fostering; Foundations; Funding; Genetic Transcription; Glues; Goals; Growth; Health; Hibernation; Human Resources; IACUC; Individual; Institutes; Interdisciplinary Study; Journals; Lead; Leadership; Longevity; Mammals; Medical Research; Mentors; Metabolic; Metabolic Diseases; Metabolism; Modeling; Muscular Atrophy; Nutritional; Phase; Pilot Projects; Prevention; Proteins; Research; Research Infrastructure; Research Institute; Research Personnel; Research Project Grants; Science; Seeds; Sequence Analysis; Structure; Study Section; Teacher Professional Development; Training; Translating; Translational Research; United States National Institutes of Health; United States Office of Research Integrity; Universities; Vision; Visualization; animal resource; biomedical scientist; collaborative environment; college; experience; microbial; microbiome research; multidisciplinary; next generation; organizational structure; professor; programs; supportive environment; translational approach; translational scientist

Project Summary -Administrative Core The Administrative Core will provide the oversight necessary to first establish the Center in Transformative Research in Metabolism at the University of Alaska during COBRE Phase I and then will ensure the long-term sustainability of the center through all three COBRE Phases and beyond. Leadership of the Administrative Core takes two forms: administrative and scientific. The Center Director, Dr. Kelly Drew, will lead administrative components. Scientific leadership and professional advising is shared by the External Advisory Committee members, the Translational Advisory Committee members, President's Professors and NIH-funded advisors/collaborators. Dr. Drew is a nationally recognized leader in the study of hibernation and metabolism, the scientific focus of the C-TRiM and has extensive administrative and mentoring experience. The External Advisory Committee will assist Dr. Drew in C-TRiM-related oversight decisions and guide the Faculty Development Plans that will enhance the ability of investigators to compete for complementary NIH individual research grants or other equivalent extramural support, and ensure the longevity of the C-TRiM as a thematic, multi-disciplinary, state-of-the-art research center in metabolism. The short- term goal for the Phase I COBRE is to lay the foundation for achieving the long-term goal by implementing administrative oversight of the center, executing the Faculty Development Plans for the C-TRiM Project Leaders, establishing productive and efficient Core Facilities, overseeing a Pilot Project Program to seed the growth of junior faculty in the center and providing critical evaluation of progress. To achieve the long-term and short-term goals of the C-TRiM, the center leadership will pursue the following Specific Aims in the Administrative Core: SA1. Create a supportive environment for the training and advising of basic and translational scientists. SA2. Establish two new technical cores to support scientific goals of the Center. SA3. Define translational paths for basic science research in mammalian hibernation SA4. Manage and administer the Pilot Project program. When complete the C-TRiM will be the first biomedical research center in the US to adopt hibernation as a model of natural adaptations in metabolism as an approach to solve complex clinical problems in the treatment of metabolic disease.

项目摘要 - 管理核心 行政核心将提供首先建立变革性中心所需的监督 在第一阶段，阿拉斯加大学代谢研究，然后将确保长期 中心通过所有三个毛线阶段及以后的可持续性。行政的领导 核心采用两种形式：行政和科学。中心主任凯利·德鲁（Kelly Drew）将领导行政 成分。科学领导和专业建议由外部咨询委员会共享 成员，翻译咨询委员会成员，总裁教授和NIH资助 顾问/合作者。 Drew博士是全国认可的冬眠和代谢研究的领导者， C-Trim的科学重点，并具有广泛的行政和指导经验。外部 咨询委员会将协助Drew博士做出与C-TRIM相关的监督决定，并指导教师 开发计划将增强调查人员争夺互补NIH个人的能力 研究授予或其他等效的壁外支持，并确保C-Trim作为主题的寿命， 多学科的新陈代谢研究中心。第一阶段毛绒的短期目标 是通过对中心进行行政监督来为实现长期目标奠定基础， 为C-TRIM项目负责人执行教师发展计划，建立富有成效的 核心设施，监督一个试点项目计划，以播种中心的初级教师的成长 提供对进度的批判性评估。为了实现C-Trim的长期和短期目标， 中心领导将在行政核心中追求以下特定目标：SA1。创建一个支持 培训和建议基础科学家的环境。 SA2。建立两个新技术 支持该中心科学目标的核心。 SA3。定义基础科学研究的翻译路径 哺乳动物冬眠SA4。管理和管理试点项目计划。完成C-Trim时 将是美国第一个采用冬眠作为自然适应模型的生物医学研究中心 代谢作为解决代谢疾病治疗中复杂临床问题的一种方法。