Administrative Core

行政核心

• 批准号: 10455076
• 负责人: KELLY L DREW
• 金额: $ 148.44万
• 依托单位: UNIVERSITY OF ALASKA FAIRBANKS
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-16 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10455076
• 关键词: Adopted; Advisory Committees; Aging; Alaska; Arctic Regions; Arts; Basic Science; Bioinformatics; Biological Sciences; Biology; Biomedical Research; Biometry; Centers of Research Excellence; Clinical; Coke; Collaborations; Committee Members; Complex; Core Facility; Development; Development Plans; Doctor of Philosophy; Educational workshop; Ensure; Environment; Essential Amino Acids; Evaluation; Experimental Designs; Extramural Activities; Faculty; Fostering; Foundations; Funding; Genetic Transcription; Glues; Goals; Growth; Health; Hibernation; Human Resources; IACUC; Individual; Institutes; Interdisciplinary Study; Journals; Lead; Leadership; Longevity; Mammals; Medical Research; Mentors; Metabolic; Metabolic Diseases; Metabolism; Modeling; Muscular Atrophy; Nutritional; Phase; Pilot Projects; Prevention; Proteins; Research; Research Infrastructure; Research Institute; Research Personnel; Research Project Grants; Science; Seeds; Sequence Analysis; Structure; Study Section; Teacher Professional Development; Training; Translating; Translational Research; United States National Institutes of Health; United States Office of Research Integrity; Universities; Vision; Visualization; animal resource; biomedical scientist; collaborative environment; college; experience; microbial; microbiome research; multidisciplinary; next generation; organizational structure; professor; programs; supportive environment; translational approach; translational scientist

Project Summary -Administrative Core The Administrative Core will provide the oversight necessary to first establish the Center in Transformative Research in Metabolism at the University of Alaska during COBRE Phase I and then will ensure the long-term sustainability of the center through all three COBRE Phases and beyond. Leadership of the Administrative Core takes two forms: administrative and scientific. The Center Director, Dr. Kelly Drew, will lead administrative components. Scientific leadership and professional advising is shared by the External Advisory Committee members, the Translational Advisory Committee members, President's Professors and NIH-funded advisors/collaborators. Dr. Drew is a nationally recognized leader in the study of hibernation and metabolism, the scientific focus of the C-TRiM and has extensive administrative and mentoring experience. The External Advisory Committee will assist Dr. Drew in C-TRiM-related oversight decisions and guide the Faculty Development Plans that will enhance the ability of investigators to compete for complementary NIH individual research grants or other equivalent extramural support, and ensure the longevity of the C-TRiM as a thematic, multi-disciplinary, state-of-the-art research center in metabolism. The short- term goal for the Phase I COBRE is to lay the foundation for achieving the long-term goal by implementing administrative oversight of the center, executing the Faculty Development Plans for the C-TRiM Project Leaders, establishing productive and efficient Core Facilities, overseeing a Pilot Project Program to seed the growth of junior faculty in the center and providing critical evaluation of progress. To achieve the long-term and short-term goals of the C-TRiM, the center leadership will pursue the following Specific Aims in the Administrative Core: SA1. Create a supportive environment for the training and advising of basic and translational scientists. SA2. Establish two new technical cores to support scientific goals of the Center. SA3. Define translational paths for basic science research in mammalian hibernation SA4. Manage and administer the Pilot Project program. When complete the C-TRiM will be the first biomedical research center in the US to adopt hibernation as a model of natural adaptations in metabolism as an approach to solve complex clinical problems in the treatment of metabolic disease.

项目概要-行政核心 行政核心将为首先建立变革中心提供必要的监督 COBRE 第一阶段期间阿拉斯加大学的新陈代谢研究将确保长期 该中心在所有三个 COBRE 阶段及以后的可持续性。行政领导 核心有两种形式：行政和科学。中心主任 Kelly Drew 博士将领导行政事务 成分。外部咨询委员会共享科学领导和专业建议 成员、转化咨询委员会成员、校长教授和 NIH 资助的 顾问/合作者。德鲁博士是全国公认的冬眠和新陈代谢研究领域的领军人物， C-TRiM 的科学重点，并拥有丰富的管理和指导经验。外部 咨询委员会将协助 Drew 博士做出与 C-TRiM 相关的监督决策并指导学院 提高研究人员竞争 NIH 互补个人能力的发展计划 研究补助金或其他同等的外部支持，并确保 C-TRiM 作为主题的长期存在， 多学科、最先进的新陈代谢研究中心。 COBRE 第一阶段的短期目标 是通过对中心实施行政监督，为实现长远目标奠定基础， 执行 C-TRiM 项目负责人的教师发展计划，建立富有成效和高效的 核心设施，监督试点项目计划，以促进中心初级教师的成长， 提供对进展的严格评估。为了实现 C-TRiM 的长期和短期目标， 中心领导层将在行政核心中追求以下具体目标：SA1。创造一个支持性的 基础科学家和转化科学家的培训和咨询环境。 SA2。建立两项新技术 支持该中心科学目标的核心。 SA3。定义基础科学研究的转化路径 哺乳动物冬眠 SA4。管理和管理试点项目计划。完成 C-TRiM 后 将成为美国第一个采用冬眠作为自然适应模型的生物医学研究中心 代谢作为解决代谢疾病治疗中复杂临床问题的一种方法。