Core A: Administrative

项目摘要 行政、宣传、规划和沟通核心（行政核心-核心A）的作用是 协调和整合Dana-Farber/哈佛癌症中心（DF/HCC）的多个组成部分 乳腺癌孢子，并提供科学，行政和财政监督孢子项目， 核心，发展研究计划（DRP）和职业提升计划（CEP）。 行政管理：核心A将促进DF/HCC内乳腺孢子的协调， 满足我们的科学目标。核心A将为乳腺癌的财政和行政监督提供基础设施 癌症孢子，包括财务会计和报告，研究协议的协调和前期和 与达纳-法伯赠款管理办公室密切合作，进行授标后监测和报告 癌症研究所. 临床研究管理：核心A将支持Breast SPORE的所有研究者开展临床研究。 在临床研究的准备、审查和启动过程中促进互动和合作 在DF/HCC乳腺项目和外部研究中心内。 在DF/HCC中整合SPORE：核心A将促进SPORE与 研究人员、DF/HCC及其领导层、DF/HCC乳腺项目及其既定委员会， 支持临床试验开发、审查、激活和管理，以及访问和使用 生物样本和相关临床数据。核心A将协调共享资源领导委员会 由核心主任、项目负责人、患者倡导者和DF/HCC研究者组成， 研究进展会议，以经常更新乳腺孢子的进展。 患者倡导：核心将整合我们的大型和高度互动的患者倡导工作 在Elizabeth Frank，EdM的指导下， 核心A的共同研究者。核心将寻求在四个SPORE项目中充分吸引病人的拥护者， DRP、CEP和核心，以确保在 临床/转化研究。 规划和评估：核心A将为SPORE提供严格的科学领导和监督 项目、核心、DRP和CEP。核心A将组织Breast SPORE外部会议 咨询委员会（EAB）和内部咨询委员会（IAB），负责评估整个 乳房孢子。

PROJECT SUMMARY The role of the Administration, Advocacy, Planning and Communication Core (Administrative Core - Core A) is to coordinate and integrate the multiple components of the Dana-Farber/Harvard Cancer Center (DF/HCC) Breast Cancer SPORE and to provide scientific, administrative and fiscal oversight of the SPORE Projects, Cores, the Developmental Research Program (DRP) and the Career Enhancement Program (CEP). Administrative Management: Core A will facilitate the coordination of the Breast SPORE within the DF/HCC to meet our scientific aims. Core A will provide the infrastructure for fiscal and administrative oversight for the Breast Cancer SPORE, including financial accounting and reporting, coordination of research agreements and pre-and post-award monitoring and reporting in close collaboration with the grants management office at Dana-Farber Cancer Institute. Clinical Research Management: Core A will support all investigators in the Breast SPORE conducting clinical trials and facilitate the interaction and collaborations in the preparation, review and activation of clinical studies within the DF/HCC Breast Program and external sites. Integration of SPORE within DF/HCC: Core A will promote coordination and communication between SPORE investigators, the DF/HCC and its leadership, the DF/HCC Breast Program and its established committees that support clinical trial development, review, activation and management, as well as access and use of biospecimens and associated clinical data. Core A will coordinate the Shared Resources Leadership Committee comprised of the core directors, project leaders, patient advocates and DF/HCC investigators, as well as monthly Research-in-Progress meetings for frequent updates on progress in the Breast SPORE. Patient Advocacy: The Core will integrate the work of our large and highly interactive Patient Advocacy Committee into the planning and evaluation of the Breast SPORE, with guidance from Elizabeth Frank, EdM, as co-investigator of Core A. The Core will seek to fully engage the patient advocates in the four SPORE Projects, the DRP, the CEP and the Cores to ensure that the patient perspective is taken into account in the clinical/translational research. Planning and Evaluation: Core A will provide rigorous scientific leadership and oversight for the SPORE Projects, the Cores, the DRP and the CEP. Core A will organize meetings of the Breast SPORE External Advisory Board (EAB) and Internal Advisory Board (IAB) for evaluation on findings and progress across the Breast SPORE.