Center for Methodologies for Adapting and Personalizing Prevention, Treatment and Recovery Services for SUD and HIV (MAPS Center)

SUD 和 HIV 预防、治疗和康复服务调整和个性化方法中心（MAPS 中心）

• 批准号: 10640287
• 负责人: Daniel Almirall
• 金额: $ 264.42万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10640287
• 关键词: Address; Adoption; Behavior; Caring; Clinic; Cocaine; Complex; Data; Data Analyses; Data Analytics; Data Collection; Development; Effectiveness; Electronic Health Record; Engineering; Ensure; Evaluation; Evidence based intervention; Experimental Designs; Generations; Grant; Guidelines; HIV; HIV Infections; Hand; Health system; Human; Incidence; Individual; International; Intervention; Mentors; Methodology; Methods; Modality; Modification; Motivation; Opioid; Outcome; Persons; Population; Positioning Attribute; Prevalence; Productivity; Recovery Support; Research; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk; Science; Scientist; Service setting; Services; Substance Use Disorder; Testing; Theory of Change; Time; Tobacco; Training; Translations; Work; adaptive intervention; addiction; analytical method; career; combat; computer science; design; digital; digital technology; effective intervention; experience; handheld mobile device; improved; individualized prevention; innovation; interest; novel; outreach; prescription opioid; prevention service; programs; public health relevance; recovery services; recruit; support tools; synergism; theories; treatment services

PROJECT SUMMARY: OVERALL Effective prevention, treatment, and recovery services for substance use disorders (SUD) and HIV demand an increasing array of evidence-based interventions to address individuals' changing strengths, needs, and circumstances. This can be achieved via adaptive interventions, which explicitly guide how to modify the type/ intensity of services based on information about the individual. Further, advances in digital technologies, such as electronic health records (EHRs) and mobile devices, have created unprecedented opportunities to obtain data for use in adapting interventions to different levels (e.g., individual, clinic, health system), modalities (e.g., digital, in-person), and/or time scales (e.g., monthly, many times a day). However, new research methodologies are needed to realize these opportunities and inform a new generation of SUD/HIV services. The focus of the proposed Center for Methodologies for Adapting and Personalizing Prevention, Treatment, and Recovery Services for SUD and HIV (MAPS Center) is the development and dissemination of novel research methodologies that are essential to optimize adaptive interventions to combat SUD/HIV. We propose three exciting, thematically integrated research projects, each developing new methods to empirically inform the construction of adaptive SUD/HIV services. Two innovative themes — optimization (i.e., developing services that achieve the best expected outcome in a way that is not too expensive, complex, or demanding to be scalable) and adaptation (i.e., using information about context and changing needs to decide when and how to intervene) — cut across these projects, enabling our team to move SUD/HIV intervention science forward while creating enormous potential for scientific synergy. Along with the three projects, two cores — Dissemination & Training Core and Administrative Core — will enable the MAPS Center to serve as a national resource by training SUD/HIV scientists in the critical use of the methods, recruiting scientists to work on optimizing adaptive SUD/HIV services, and mentoring early career scholars. The overall Specific Aims of the MAPS Center are: (Aim A) To develop novel experimental and data analytic methods to optimize the adaptation of SUD/HIV services across different levels (e.g., individual, clinic), modalities (e.g., in-person, digital), and time scales (e.g., monthly, daily); (Aim B) To serve as a national resource by placing the innovative methods developed in the MAPS Center directly into the hands of SUD/HIV scientists; and (Aim C) To nurture and build capacity among scientists to design experiments and analyze data to inform the development of adaptive SUD/HIV services. The MAPS Center will pave the way for a new generation of highly effective and scalable interventions that will reduce the prevalence and incidence of SUD and HIV infection.

项目总结：总体

项目成果

Hierarchical network models for exchangeable structured interaction processes.

用于可交换结构化交互过程的分层网络模型。

• DOI: 10.1080/01621459.2021.1896526
• 发表时间: 2022
• 期刊: Journal of the American Statistical Association
• 影响因子: 3.7
• 作者: Dempsey,Walter;Oselio,Brandon;Hero,Alfred
• 通讯作者: Hero,Alfred

A posterior expected value approach to decision-making in the multiphase optimization strategy for intervention science.

干预科学多阶段优化策略中决策的后验期望值方法。

• DOI: 10.1037/met0000569
• 发表时间: 2023
• 期刊: Psychological methods
• 影响因子: 7
• 作者: Strayhorn,JillianC;Collins,LindaM;Vanness,DavidJ
• 通讯作者: Vanness,DavidJ

Behavior change versus stability during the college-to-work transition: Life course and the "stickiness" of alcohol misuse at career entry.

从大学到工作的过渡期间的行为变化与稳定性：生命历程和职业进入时酗酒的“粘性”。

• DOI: 10.1111/peps.12519
• 发表时间: 2023
• 期刊: Personnel psychology
• 影响因子: 5.5
• 作者: Liu,Songqi;Bamberger,Peter;Wang,Mo;Nahum-Shani,Inbal;Larimer,Mary;Bacharach,SamuelB
• 通讯作者: Bacharach,SamuelB

Motivational Enhancement Interventions to Increase Pre-Exposure Prophylaxis Use in Sexual Minority Men Who Use Stimulants: Protocol for a Pilot Sequential Multiple Assignment Randomized Trial.

动机增强干预措施增加了使用兴奋剂的性少数族裔男性中暴露前预防的使用：用于飞行员顺序多次分配随机试验的方案。

• DOI: 10.2196/48459
• 发表时间: 2023-10-13
• 期刊: JMIR RESEARCH PROTOCOLS
• 影响因子: 1.7
• 作者: Davis-Ewart, Leah;Grov, Christian;Verhagen, Rachel;Manuel, Jennifer;Viamonte, Michael;Dilworth, Samantha;O'Dell, Nicole;Valentin, Omar;Carr, Sidney;Cherenack, Emily;Henderson, Chelsea;Doblecki-Lewis, Susanne;Nahum-Shani, Inbal;Carrico, Adam W
• 通讯作者: Carrico, Adam W

Effectiveness of gamified team competition as mHealth intervention for medical interns: a cluster micro-randomized trial.

• DOI: 10.1038/s41746-022-00746-y
• 发表时间: 2023-01-11
• 期刊: NPJ digital medicine
• 影响因子: 15.2