Full Scale Randomized Trial of an Innovative Conversational Agent for Smoking Cessation
创新对话式戒烟剂的全面随机试验
基本信息
- 批准号:10640842
- 负责人:
- 金额:$ 71.58万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-04-01 至 2025-03-31
- 项目状态:未结题
- 来源:
- 关键词:AbstinenceAddressAdoptedAdultAmericanAntismokingCellular PhoneCessation of lifeCloud ComputingCommunicationCommunitiesComputersCost MeasuresDissemination and ImplementationEffectivenessEmotionalFeelingGoalsHealth behavior changeInternetInterventionJudgmentKnowledgeLanguageLifeMachine LearningMalignant NeoplasmsMeasuresMediatingMediatorMedicalModelingNatural Language ProcessingOutcomeParticipantPolicy MakerPolicy MakingPopulationPrevalenceProcessPublic HealthRandomizedRandomized, Controlled TrialsResearchSample SizeSmokerSmokingSmoking Cessation InterventionSocial supportTechnologyTestingText MessagingTherapeuticTimeTrustWorkarmbehavior changecigarette smokingcomparative effectivenesscostcost effectivecost effectivenesscost per quality-adjusted life yeardemographicsdesigndiariesdigitaldigital technologyeffectiveness evaluationfollow-upimprovedinnovationnew technologypatient engagementprematureprogramspublic health relevancerandomized effectiveness trialrandomized trialresponsesexsmartphone applicationsmoking cessationsocialsuccesstext messaging interventionweb site
项目摘要
PROJECT SUMMARY/ABSTRACT (DESCRIPTION)
Cigarette smoking accounts for 480,000 premature deaths and one third of all cancer deaths annually in the
US. There is enormous need for high-impact, cost-effective population-level interventions for smoking
cessation. For the past 15 years, mobile phone-delivered text messaging interventions such as the NCI’s
SmokefreeTXT have been a prominent technology addressing this need. However, very much like all widely
available technologies for smoking cessation (e.g., websites), text messaging interventions have modest quit
rates, driven largely by low engagement. Fortunately, a new technology provides a therapeutic conversation to
address the problem of engagement that impacts text messaging and other current digital technologies for
smoking cessation. Advances in machine learning, natural language processing, and cloud computing are now
making it possible to create and widely disseminate conversational agents (CAs), which are computer-powered
digital coaches designed to form long-term social-emotional connections with users through conversations.
CAs are supportive, empathic, reflectively listen, provide personalized responses, and offer goal setting and
advice appropriately timed to the needs of the user. Regarding CAs for smoking cessation, the major
knowledge gaps are: (1) their efficacy, (2) theoretical mechanisms, and (3) the cost-effectiveness. Also
unexplored are the potential baseline moderators of CAs for smoking cessation. We recently developed a CA
for smoking cessation, called “QuitBot,” evaluated it in a diary study, and then tested it in a pilot randomized
controlled trial (N = 306), comparing it with the NCI’s SmokefreeTXT. The pilot RCT design was very feasible
with 93% three-month follow-up. QuitBot had: (a) high participant engagement and (b) high quit rates at the
three-month follow-up—very promising in comparison with SmokefreeTXT. Addressing these knowledge gaps
and building on the promising results of our QuitBot research, the project will conduct a randomized controlled
trial of QuitBot (n = 760) versus SmokefreeTXT (n = 760) with 12-month follow-up in order to determine
whether QuitBot: (1) provides higher quit rates than SmokefreeTXT, (2) has smoking cessation outcomes
significantly mediated by therapeutic alliance processes and engagement, and (3) is cost-effective vs.
SmokefreeTXT. In addition, this study will explore whether these baseline factors moderate the effectiveness
of QuitBot: trust, social support, and demographics (e.g., sex). This innovative project will advance the fields of
research on CAs both for smoking cessation in particular and for health behavior change in general—
regardless of whether the results are positive or null. Positive results could have high population-level impact
and stimulate new lines of research into CA dissemination and implementation, and the adaptation of CAs for
multiple subpopulations of smokers, languages, and community and medical settings.
项目总结/摘要(描述)
吸烟导致48万人过早死亡,占美国每年癌症死亡人数的三分之一。
我们对吸烟问题进行高影响、高成本效益的人群干预是非常必要的
停止在过去的15年里,移动的电话提供的短信干预,如国家癌症研究所的
SmokefreeTXT一直是解决这一需求的突出技术。然而,非常像所有广泛
戒烟的可用技术(例如,网站),短信干预有适度的退出
率,主要由低参与度驱动。幸运的是,一项新技术提供了一种治疗对话,
解决影响短信和其他当前数字技术的参与问题,
戒烟。机器学习、自然语言处理和云计算的进步现在已经
使创建和广泛传播计算机驱动的会话代理(CA)成为可能
数字教练旨在通过对话与用户建立长期的社交情感联系。
CA是支持性的,同情的,反思性的倾听,提供个性化的回应,并提供目标设定和
根据用户的需要适时提供建议。关于戒烟的核证机关,
知识差距是:(1)其功效,(2)理论机制,(3)成本效益。也
尚未探索的是戒烟的CA的潜在基线调节剂。我们最近开发了一种CA
戒烟,称为“QuitBot”,在日记研究中评估它,然后在一个随机的试点中测试它。
对照试验(N = 306),将其与NCI的SmokefreeTXT进行比较。试验性RCT设计非常可行
三个月随访率为93% QuitBot具有:(a)高参与者参与度和(B)高退出率,
3个月随访-与SmokefreeTXT相比非常有希望。弥补这些知识差距
在我们QuitBot研究的有希望的结果的基础上,该项目将进行一项随机对照研究,
QuitBot(n = 760)与SmokefreeTXT(n = 760)的试验,随访12个月,以确定
QuitBot是否:(1)提供比SmokefreeTXT更高的戒烟率,(2)具有戒烟效果
显著介导的治疗联盟过程和参与,(3)是成本效益与。
SmokefreeTXT。此外,本研究还将探讨这些基线因素是否会影响疗效
QuitBot:信任,社会支持和人口统计(例如,性别)。这一创新项目将推动以下领域的发展
研究CA,特别是戒烟和一般健康行为改变-
而不管结果是正还是零。积极的结果可能会产生很大的人口影响
并鼓励对保护性农业的传播和实施进行新的研究,
吸烟者、语言、社区和医疗环境的多个亚群。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Jonathan B Bricker其他文献
Parental smoking cessation and children's smoking: response to three insightful commentaries
父母戒烟和儿童吸烟:对三个富有洞察力的评论的回应
- DOI:
10.1046/j.1360-0443.2003.t01-9-00396.x - 发表时间:
2003 - 期刊:
- 影响因子:6
- 作者:
Jonathan B Bricker;B. Leroux;A. V. Peterson;Kathleen A. Kealey;I. Sarason;M. Andersen;Patrick M. Marek - 通讯作者:
Patrick M. Marek
A Behavioral Activation Mobile Health App for Smokers With Depression: Development and Pilot Evaluation in a Single-Arm Trial
针对抑郁症吸烟者的行为激活移动健康应用程序:单臂试验的开发和试点评估
- DOI:
10.2196/13728 - 发表时间:
2019 - 期刊:
- 影响因子:2.2
- 作者:
J. Heffner;Noreen L Watson;Edit Serfozo;Kristin E Mull;Laura MacPherson;Melissa L. Gasser;Jonathan B Bricker - 通讯作者:
Jonathan B Bricker
The Paradox of Avoidant Coping and Its Implications for Smoking Does Avoidant Coping Influence Young Adults’ Smoking?: A Ten-Year Longitudinal Study
回避型应对的悖论及其对吸烟的影响回避型应对会影响年轻人吸烟吗?:一项为期十年的纵向研究
- DOI:
- 发表时间:
2011 - 期刊:
- 影响因子:0
- 作者:
Jonathan B Bricker;Lara B. Schiff;B. Comstock - 通讯作者:
B. Comstock
Jonathan B Bricker的其他文献
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{{ truncateString('Jonathan B Bricker', 18)}}的其他基金
Digital smoking cessation intervention for nationally-recruited American Indians and Alaska Natives: A full-scale randomized controlled trial
针对全国招募的美洲印第安人和阿拉斯加原住民的数字戒烟干预:一项全面的随机对照试验
- 批准号:
10826067 - 财政年份:2023
- 资助金额:
$ 71.58万 - 项目类别:
Quit2Heal: Rigorous Randomized Trial of a Smartphone Application to Help Cancer Patients Stop Smoking
Quit2Heal:智能手机应用程序帮助癌症患者戒烟的严格随机试验
- 批准号:
10601285 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Telephone Delivered Acceptance & Commitment Therapy for Weight Loss
电话送达验收
- 批准号:
10176479 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Telephone Delivered Acceptance & Commitment Therapy for Weight Loss
电话送达验收
- 批准号:
10448324 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Quit2Heal: Rigorous Randomized Trial of a Smartphone Application to Help Cancer Patients Stop Smoking
Quit2Heal:智能手机应用程序帮助癌症患者戒烟的严格随机试验
- 批准号:
10646486 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Quit2Heal: Rigorous Randomized Trial of a Smartphone Application to Help Cancer Patients Stop Smoking
Quit2Heal:智能手机应用程序帮助癌症患者戒烟的严格随机试验
- 批准号:
10413165 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Telephone Delivered Acceptance & Commitment Therapy for Weight Loss
电话送达验收
- 批准号:
10686832 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Telephone Delivered Acceptance & Commitment Therapy for Weight Loss
电话送达验收
- 批准号:
10601644 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Full Scale Randomized Trial of an Innovative Conversational Agent for Smoking Cessation
创新对话式戒烟剂的全面随机试验
- 批准号:
10381470 - 财政年份:2020
- 资助金额:
$ 71.58万 - 项目类别:
Randomized Trial of an Innovative Smartphone Intervention for Smoking Cessation
创新智能手机戒烟干预措施的随机试验
- 批准号:
9086295 - 财政年份:2015
- 资助金额:
$ 71.58万 - 项目类别:
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