Genetic Dissection of Cells and Organisms Training Grant

项目摘要/摘要 细胞和生物遗传解剖培训计划(GDTP)提供 在设计和执行方面接受高级多学科博士培训的学员 实验遗传学，遗传数据集的定量分析，以及公众的理解 他们的职业生涯将在其中发挥作用的问题和担忧。GDTP是UC唯一的计划 伯克利，提供全方位的实验遗传学综合培训，从 噬菌体对人，将最先进的技术与培训和机会相结合 可通过新的数据科学学院获得。GDTP的37名培训教师获得认可 来自三个系的科学领袖，分子与细胞生物学(MCB)，植物与 微生物生物学(PMB)和综合生物学(IB)，以及 微生物学。这项提案要求为16名学员提供第二年和第三年的支持 在他们选择遗传学作为他们研究的重点之后，进行博士培训。 GDTP在灵活的结构中提供以学生为中心的早期和持续的培训。 所有学生都必须选修实验遗传学、数据分析、编码和 统计；基因组编辑；负责任的行为和研究的再现性。GDTP的 签名每周遗传学沉浸要求跨越两年。它包括直接交互 与领先的遗传学家合作；对当代遗传学论文的批判性评价，包括那些 公布了该领域的重大错误以及这些错误是如何发生的，然后 以及及时的伦理主题和研究中负责任的行为的交织。 一年一度的活动包括实习生迎新和年度务虚会，这将为学生做好准备 在区域和国家会议上介绍他们的工作。该计划提供专业的 职业咨询和一套科学传播的职业发展计划， 教学、赠款撰写和出版、团队合作、管理和领导力。 所有受训人员都将得到针对其个人的广泛咨询和指导 职业目标。密切跟踪学生的进步确保正在苦苦挣扎的实习生 得到及时的支持。GDTP的评估过程自始至终都在征求内部和外部意见 这一年，确保持续改进计划。雄心勃勃的招聘和留住 计划--包括所有培训人员的积极参与--将被用于确保 代表人数不足的少数群体的成员、妇女和 残疾或其他处境不利的学生。

Project Summary/Abstract The Genetic Dissection of Cells and Organisms Training Program (GDTP) provides trainees with advanced multidisciplinary PhD training in the design and execution of experimental genetics, quantitative analysis of genetic datasets, and understanding of the public issues and concerns among which their careers will play out. GDTP is the only program at UC Berkeley that provides integrated training across the full range of experimental genetics, from phage to human, integrating the most advanced technologies with the training and opportunities available through the new School of Data Science. GDTP's 37 training faculty are recognized scientific leaders, drawn from three departments, Molecular & Cell Biology (MCB), Plant & Microbial Biology (PMB), and Integrative Biology (IB), and from the Graduate Group in Microbiology. This proposal requests support for 16 trainees in their second and third years of PhD training after they have selected genetics as the focus of their research. GDTP provides early and persistent student-centered training within a flexible structure. All students must take graduate-level courses in experimental genetics; data analysis, coding, and statistics; genome editing; and responsible conduct and reproducibility in research. GDTP's signature Weekly Genetics Immersion is required across both years. It includes direct interaction with leading geneticists; critical evaluation of contemporary papers in genetics, including those that published major mistakes in the field and how those mistakes were made and then uncovered; and interweaving of timely topics in ethics and responsible conduct in research. Annual events include a trainee orientation and an Annual Retreat which will prepare students for presenting their work at regional and national meetings. The program provides professional career counseling and a suite of professional development programs in science communication, teaching, grant-writing and publishing, teamwork, management, and leadership. All trainees will receive extensive individual advising and mentoring tailored to their career objectives. Close tracking of student progress ensures that trainees who are struggling receive timely support. GDTP's evaluation process solicits internal and external input throughout the year, ensuring continuous program improvement. An ambitious recruitment and retention plan—involving the active participation of all training faculty—will be employed to ensure participation and full inclusion of members of underrepresented minorities, women, and disabled or otherwise disadvantaged students.