Center of Biomedical Research Excellence in Cardiovascular Health Research Core

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PROJECT SUMMARY/ABSTRACT The goal of the University of Delaware Center of Biomedical Research Excellence in Cardiovascular Health is to continue to support multidisciplinary research aimed toward understanding the mechanisms underlying the causes and consequences of poor cardiovascular health and/or function, and developing effective interventions for these conditions. During Phase I our COBRE Research Core acquired equipment and supported personnel that was instrumental in the advancement of our project leaders to R01 funding. In addition to COBRE projects, the core has also supported a number of other NIH funded projects through both access to equipment and personnel. The COBRE Research Core includes a Cardiovascular Research Core (CVRC) that provides instrumentation and personnel, biostatistical support, and bioimaging support through the Bio-Imaging Center. The establishment of the CVRC in Phase I took advantage of the Cardiovascular Physiology Labs that had been constructed at UD to facilitate cardiovascular research in the Health Sciences Complex. The core expanded its footprint over the course of Phase I as the needs of investigators continued to grow. In Phase II the core will be led by a new core director, will add personnel for the management of equipment and facilities, acquire additional ultrasound imaging equipment and upgrade confocal microscopy capabilities in the Bio-imaging Center. The proposed Phase II COBRE in Cardiovascular Health will capitalize on our success and momentum from Phase I and the Research Core will continue to be the research hub of this COBRE accelerating the pace of investigation in the center. The continued success and sustainability of the center depends on strengthening the administrative framework and the infrastructure for the growing cardiovascular research at UD in order to support project investigators and other investigators at UD.