Research in practice: translating infectious disease epidemiology RIP-TIDE

实践研究：转化传染病流行病学 RIP-TIDE

• 批准号: 10640155
• 负责人: WILLIAM J MOSS
• 金额: $ 32.38万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10640155
• 关键词: Infectious Disease Epidemiology; Translating; research in practice

PROJECT SUMMARY / ABSTRACT Public health response to infectious disease epidemics requires multidisciplinary, quantitative, and critical skills to address all aspects of control from preparedness to elimination. The proposed training program will provide critical training in modern methods of infectious disease epidemiology within the Department of Epidemiology at the Johns Hopkins Bloomberg School of Public Health. All trainees in this program will receive rigorous training in three foundational areas: Epidemiologic Study Design and Inference, Ethics, and Translating Infectious Disease Research through an applied practicum. In addition, trainees will focus on one of three areas of methodological specialization (1) Transmission Modeling and Infectious Disease Dynamics, (2) Molecular Epidemiology and Phylogenetics, or (3) Disease Mapping and Burden Estimation. These three areas of specialization were selected because of their importance across all phases of the response to infectious disease threats, from preparedness, through emergence, endemic control and elimination. The core faculty and affiliate faculty participating in this training program bring strong expertise in each of these areas of methodological specialization, as well as deep expertise in a large number of pathogen systems, and lead projects that offer numerous training opportunities in these areas. Emphasis will be placed on integrating and translating epidemiological and scientific results to public health policy and practice. All trainees will be provided with practical experience in translational research and implementation science through practicums and research projects. Hence, trainees will be required devote a research aim to applying advanced methods to policy and practice. Two post-doctoral and 2-3 pre-doctoral trainees will be supported in each year of the program, and will be paired with both methodological area and pathogen specific mentors. By focusing on critical methodological areas, this training program will provide critical skills that will prepare trainees to conduct important and impactful research in all phases of the infectious disease ‘lifecycle’, from emergence to elimination.

项目摘要/摘要 应对传染病流行的公共卫生需要多学科、量化和关键技能 处理从准备到消除的所有方面的控制。拟议的培训方案将提供 流行病学系内现代传染病流行病学方法的关键培训 在约翰霍普金斯大学布隆伯格公共卫生学院。所有参加该计划的学员都将受到严格的 三个基本领域的培训：流行病学研究设计和推断、伦理学和翻译 通过应用实践进行传染病研究。此外，受训者将专注于以下三项中的一项 方法学专门化领域(1)传播建模和传染病动力学，(2) 分子流行病学和系统发生学，或(3)疾病图谱和负担估计。这三个领域 之所以选择专业化，是因为它们在应对传染病的所有阶段都很重要 疾病威胁，从防备到出现、地方病控制和消除。核心教员 和参与此培训计划的附属教员在以下每个领域都带来了强大的专业知识 方法的专业化，以及在大量病原体系统和铅的深厚专业知识 在这些领域提供大量培训机会的项目。重点将放在整合和 将流行病学和科学成果转化为公共卫生政策和实践。所有实习生都将成为 通过实践提供翻译研究和实施科学的实践经验 和研究项目。因此，学员将被要求致力于应用先进方法的研究目标 为了政策和实践。每年将支持2名博士后和2-3名博士后实习生 计划，并将与方法学领域和病原体特定导师配对。通过专注于 关键方法领域，该培训计划将提供关键技能，使受训者做好准备 在传染病“生命周期”的所有阶段进行重要和有影响力的研究，从出现到 淘汰赛。

项目成果

Comparison of allocation strategies of convalescent plasma to reduce excess infections and mortality from SARS-CoV-2 in a US-like population.

比较恢复期血浆分配策略以减少类似美国人群中 SARS-CoV-2 的过度感染和死亡率。

• DOI: 10.1111/trf.17174
• 发表时间: 2023
• 期刊: Transfusion
• 影响因子: 2.9
• 作者: Kostandova,Natalya;Drabo,EmmanuelFulgence;Yenokyan,Karine;Wesolowski,Amy;Truelove,Shaun;Bloch,EvanM;Tobian,AaronAR;Vassallo,RalphR;Bravo,MarjorieD;Casadevall,Arturo;Lessler,Justin;Lau,Bryan
• 通讯作者: Lau,Bryan