Cancer Center Support Grant

癌症中心支持补助金

• 批准号: 10643036
• 负责人: BENJAMIN G. NEEL
• 金额: $ 15万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10643036
• 关键词: Address; Area; Basic Science; Cancer Biology; Cancer Burden; Cancer Center; Cancer Center Support Grant; Cancer Control; Cancer Etiology; Catchment Area; Cellular biology; Cities; Clinic; Clinical Research; Clinical Sciences; Clinical Trials; Community Outreach; Conduct Clinical Trials; Correlative Study; Development; Education; Epidemiology; Faculty; Faculty Recruitment; Funding; Genetic; Geography; Gifts; Goals; Health Policy; Health system; High School Student; House Staffs; Individual; Institutes; Laboratory Scientists; Leadership; Long Island; Malignant Neoplasms; Medical Students; Medicine; Mentorship; NCI-Designated Cancer Center; New York; New York City; Nursing Students; Outcome; Patients; Peer Review; Phase; Population; Population Sciences; Provider; Public Health; Research; Research Personnel; Resource Sharing; Schools; Science; Scientist; Strategic Planning; Strategic vision; System; Time; Training and Education; Translating; Translational Research; Translations; Universities; Weather; anticancer research; base; cancer care; cancer cell; cancer epidemiology; cancer genome; cancer health disparity; cancer therapy; cancer type; college; community engagement; disorder control; graduate student; health disparity; improved; innovation; insight; medical schools; melanoma; member; next generation; outreach program; patient oriented; patient population; population health; precision medicine; programs; recruit; research facility; senior faculty; tumor immunology; undergraduate student

Project Summary Since the last competitive review of this Cancer Center Support Grant (CCSG) in 2012, the NCI-designated Perlmutter Cancer Center (PCC), previously NYU Cancer Institute, has weathered the devastation of Superstorm Sandy and emerged into a period of profound transformation and expansion. Propelled by a transformative gift from Laurie and Isaac Perlmutter, renewed and enhanced institutional support from the NYU Langone Health system (NYULH) and a new Director, we have overhauled our leadership team, expanded our clinical and research facilities, and developed a new strategic vision and began implementing a new Strategic Plan. Guided by this plan, our Scientific Programs and Shared Resources have been restructured, and we embarked on a major recruitment campaign that has yielded 12 additional new leadership and/or senior faculty recruits, 15 other new cancer center faculty recruits, and 68 new members overall. Under revised, more stringent criteria, membership has been streamlined to 180 full members and 56 associate members. Members carry out research as part of 5 Scientific Programs, Cancer Genome Dynamics, Cancer Cell Biology, Tumor Immunology, Melanoma, or Epidemiology and Cancer Control, assisted by 10 Shared Resources and 2 Developing Shared Resources. Our clinical trials office has been reorganized and substantially expanded under new leadership and a new Phase I unit has opened. Subsequently, trial availability, quality, and accrual have increased, while the time to trial opening has been markedly reduced. In line with our increased geographic scope and patient population, we have redefined and enlarged our catchment area. Aided by the creation of a new Department of Population Health at NYU Langone School of Medicine and the College of Global Public Health at the NYU main campus, our Population Sciences research has increased in breadth and quality. Most importantly, our laboratory scientists have made paradigm-shifting discoveries, our clinicians have led multiple practice-changing trials, and our population scientists have yielded new insights into the causes of cancer and how to control the disease, contributed to major public health policy changes and initiatives, and established new community outreach programs that address the specific cancer burdens and health disparities in our catchment area. Although PCC is located in a city with four other NCI-designated cancer centers, our catchment area differs substantially from the others: we are the major provider to lower Manhattan, and have expanded into Brooklyn, the largest and fastest growing borough in New York City, as well as to Queens and Long Island.

项目概要 自 2012 年对该癌症中心支持补助金 (CCSG) 进行最后一次竞争性审查以来，NCI 指定的 珀尔马特癌症中心 (PCC)（前身为纽约大学癌症研究所）经受住了超级风暴的破坏 桑迪进入了一个深刻变革和扩张的时期。受到变革性礼物的推动 Laurie 和 Isaac Perlmutter 的支持，纽约大学兰格尼健康中心更新并加强了机构支持 系统（NYULH）和新主任，我们彻底改革了我们的领导团队，扩大了我们的临床和 研究设施，制定了新的战略愿景并开始实施新的战略计划。引导 通过这个计划，我们的科学计划和共享资源已经重组，我们开始了 重大招聘活动已新增 12 名新领导和/或高级教员，另外 15 名其他人员 癌症中心新聘教员，共有 68 名新成员。根据修订后的更严格的标准， 成员已精简为 180 名正式成员和 56 名准成员。成员开展研究 作为 5 个科学计划的一部分，癌症基因组动力学、癌细胞生物学、肿瘤免疫学、 黑色素瘤，或流行病学和癌症控制，由 10 个共享资源和 2 个开发共享资源协助 资源。我们的临床试验办公室在新的领导层和领导下进行了重组和大幅扩展 一个新的一期单元已经开业。随后，试验的可用性、质量和应计费用都得到了提高，而 试营业时间显着缩短。根据我们扩大的地理范围和患者 人口，我们重新定义并扩大了我们的服务范围。在新成立的部门的帮助下 纽约大学朗格尼医学院的人口健康和纽约大学主校区的全球公共卫生学院 校园内，我们的人口科学研究的广度和质量都有所提高。最重要的是我们的实验室 科学家们取得了改变范式的发现，我们的临床医生领导了多项改变实践的试验，并且 我们的人口科学家对癌症的成因以及如何控制这种疾病有了新的见解， 促进了重大公共卫生政策的变化和举措，并建立了新的社区外展活动 解决我们学区特定癌症负担和健康差异的计划。虽然PCC 位于一个拥有其他四个 NCI 指定癌症中心的城市，我们的服务区域与 其他：我们是曼哈顿下城的主要供应商，并已扩展到布鲁克林，这是最大的、最 纽约市以及皇后区和长岛发展最快的行政区。