Addressing the Research Capacity Gap in Global Child and Adolescent Health Disparities Utilizing Implementation and Data Sciences among Vulnerable Populations in Resource-limited Settings (ACHIEVE)

利用资源有限环境中弱势群体的实施和数据科学来解决全球儿童和青少年健康差异的研究能力差距（ACHIEVE）

• 批准号: 10644158
• 负责人: Theresa Stichick Betancourt
• 金额: $ 4万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10644158
• 关键词: Active Learning; Address; Adolescent; Adult; Affect; Africa South of the Sahara; Asia; Caregivers; Child; Child Health; Collaborations; Consultations; Country; Data Science; Eastern Europe; Emerging Communicable Diseases; Ensure; Family; Family health status; Funding; Goals; Graduate Degree; Health; Health Professional; Healthcare Systems; Immersion; Incidence; Knowledge; Learning; Light; Mentors; Mentorship; Methodology; Monitor; Online Systems; Outcome; Pattern; Population; Populations at Risk; Postdoctoral Fellow; Public Health; Research; Research Methodology; Research Personnel; Research Training; Resource-limited setting; Time; Training; Training Programs; Translations; Universities; Vulnerable Populations; adolescent health; burden of illness; cohort; dissemination science; global health; health care disparity; health disparity; health inequalities; implementation science; low and middle-income countries; programs; skills; trend; uptake

PROJECT ABSTRACT Significant advances in global health have been achieved in recent decades. Yet, serious disparities in health outcomes persist, especially among children, adolescents and their adult caregivers. Sub-Saharan Africa (SSA) is one of the regions disproportionately burdened by multiple health threats, including endemic CDs; emerging and re-emerging infectious diseases; increasing incidence of NCDs, and a set of exacerbating factors that have contributed to poor public health and increased overall disease burden affecting children, adolescents and their adult caregivers. Similar trends are documented in several other LMICs, including countries in Asia and Eastern Europe. In light of widespread health inequities and gaps in the translation and uptake of scientific evidence in real-world settings in LMICs, dissemination and implementation (D&I) science can advance timely and context- specific public health solutions. Moreover, significant methodological advances in data science can create new opportunities to more accurately identify at-risk populations, better understand patterns and mechanisms of health burdens, and allow for more in-depth analysis of implementation gaps and disparities in healthcare systems and across populations in LMICs. The proposed research training program, entitled “Addressing the Research Capacity Gap in Global Child, Adolescent & Family Health Disparities Utilizing Implementation and Data Sciences among Vulnerable Populations in Resource-limited Settings (ACHIEVE)”, focuses on increasing D&I and data science capacity to address global health disparities affecting children, adolescents and their adult caregivers. The program addresses the following specific aims: Aim 1: To provide a research training program to five cohorts (~50 trainees) of health care professionals and post-doctoral trainees from the U.S., and post-professional degree graduates from SSA that equips trainees with D&I and data science research skills and knowledge through experiential learning, mentoring, “hands-on” immersion in global health implementation and data science research and methodologies, individualized consultation, goal setting and monitoring and web- based support across time; Aim 2: Bring together an interprofessional network of committed mentors from the global north and the global south to promote equitable bi-directional learning and collaboration and ensure quality training for promising new investigators committed to applying D&I and data science research methods to address health disparities impacting children, adolescents, and their families in low-resource settings; Aim 3: To examine the short-term and longitudinal outcomes of the ACHIEVE training program; and Aim 4. Delineate key factors that underlie successful mentorship and training of new investigators– with potential implications for new investigators who are focused on D&I and data science research that seek to address health disparities impacting children, adolescents, and their adult caregivers. The four U.S. universities have each committed matching funds totaling $600,000 to support the ACHIEVE program.

项目摘要 近几十年来，全球卫生领域取得了重大进展。然而，健康方面的严重差距 结果仍然存在，特别是在儿童、青少年及其成年照顾者中。撒哈拉以南非洲(SSA) 是不成比例地背负着多种健康威胁的区域之一，包括地方性CD；正在出现 和再次出现的传染病；非传染性疾病发病率的增加，以及一系列加剧因素，这些因素 导致公共卫生状况不佳，增加了影响儿童、青少年和儿童的总体疾病负担 成人照顾者。其他几个低收入国家也出现了类似的趋势，包括亚洲和东方国家 欧洲。鉴于在翻译和吸收科学证据方面普遍存在的卫生不平等和差距， 在LMIC、传播和实施(D&I)科学的现实世界环境中，科学可以及时地和背景地- 具体的公共卫生解决方案。此外，数据科学在方法论上的重大进步可以创造新的 有机会更准确地识别高危人群，更好地了解 卫生负担，并允许更深入地分析医疗保健方面的实施差距和差距 LMIC中的系统和跨人群。拟议的研究培训方案，题为“解决 全球儿童、青少年和家庭健康差距研究能力差距的实施 在资源有限的环境中的弱势群体中的数据科学(ACCESS)“，重点是 提高研发和数据科学能力，以解决影响儿童、青少年和 他们的成年照顾者。该方案涉及以下具体目标：目标1：提供研究培训 向来自美国的五批(约50名实习生)卫生保健专业人员和博士后实习生提供培训计划，以及 从SSA毕业的专业后学位毕业生，为学员提供D&I和数据科学研究技能，并 通过体验式学习、指导、“动手”沉浸于全球卫生实施和 数据科学研究和方法、个性化咨询、目标设定和监测以及网络- 基于时间的支持；目标2：汇聚由来自 全球北方和全球南方，促进公平的双向学习和合作，确保质量 对致力于将D&I和数据科学研究方法应用于 解决影响低资源环境中儿童、青少年及其家庭的健康差距；目标3： 检查实现培训计划的短期和纵向成果；目标4.描述关键 成功指导和培训新调查人员的因素--对新调查人员的潜在影响 专注于研发和数据科学研究的调查人员，这些研究试图解决影响健康差距的问题 儿童、青少年及其成年照顾者。这四所美国大学都承诺提供等额资金 总计60万美元，以支持ALABLE计划。