Progressive Muscle Relaxation for Chronic Pain in an Acute Care Setting

渐进式肌肉放松治疗急性护理环境中的慢性疼痛

• 批准号: 10648574
• 负责人: Mia Minen
• 金额: $ 5.4万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-01-12 至 2023-09-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10648574
• 关键词: Accident and Emergency department; Acute Pain; Adherence; Adverse effects; Advisory Committees; Affect; American; Analgesics; Area; Behavior; Behavioral Research; Cellular Phone; Characteristics; Chronic Care; Chronic disabling pain; Clinical; Clinical Investigator; Clinical Research; Clinical Trials; Comparative Effectiveness Research; Complementary Health; Data; Discharge Plannings; Emergency Medicine; Emergency department visit; Epilepsy; Evidence based intervention; Feedback; Foundations; Frequencies; Funding; Future; Goals; Headache; Health Services; Integrative Medicine; Interdisciplinary Study; Intervention; Intervention Studies; Interview; Measures; Medical; Medical center; Medicine; Mental Depression; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methodology; Methods; Migraine; Mind-Body Intervention; Monitor; Muscle relaxation phase; New York; Nutraceutical; Outcome; Pain; Pain Research; Pain management; Pain-Free; Participant; Patients; Pharmaceutical Preparations; Physicians; Prevention; Process; Provider; Psychologist; Public Health; Qualitative Methods; Questionnaires; Randomized; Randomized Clinical Trials; Relaxation; Reporting; Research; Research Design; Research Methodology; Research Personnel; Research Training; Science; Self Efficacy; Self Management; Standardization; Stress; Symptoms; Techniques; Technology; Testing; Training; Translating; United States; Universities; Variant; Visit; World Health Organization; acceptability and feasibility; acute care; arm; base; body-mind; chronic pain; chronic pain patient; chronic painful condition; demographics; diaries; disability; effective intervention; efficacy evaluation; evidence base; experience; follow-up; health care service utilization; improved; intervention program; knowledge base; mHealth; medical specialties; migraine treatment; non-opioid analgesic; novel; pain self-management; population health; prevent; primary care setting; primary outcome; prototype; randomized controlled study; recruit; research study; satisfaction; secondary outcome; skills; sleep quality; smartphone Application; standard of care; statistics; therapy development; treatment as usual; treatment planning; trend; usability; usual care arm

PROJECT SUMMARY/ABSTRACT The overall goals of this proposed project are 1) to develop Dr. Mia Minen into a pain researcher in integrative and complementary health with skills to conduct independent multidisciplinary research; and 2) to conduct a clinical research study to assess the feasibility and acceptability of a relaxation intervention for migraine patients who present to the emergency department (ED). Dr. Minen will develop and advance her knowledge base, experience, and skills in 5 key areas through mentored training: 1) Mind-body intervention (MBI) techniques; 2) Advanced research methods (in health services, clinical trials, and mobile health strategies); 3) Emergency medicine pain research methodology and responsible conduct; 4) New research design frameworks; and 5) Prevention science, program intervention development, and comparative effectiveness research. The long-term goal of the research training is to be able to independently develop, assess, refine, and compare novel and existing evidence-based MBIs for migraine patients across medical specialties, with a special focus on the emergency medicine and primary care settings. In addition, the purpose of the training is to gain advanced skills to study the MBIs alone and in combination with nutraceuticals and medications. The research proposed in this K23 application is important to understanding how evidence-based MBIs can be made more accessible for chronic pain patients in the acute care setting. It helps to set the framework for translating evidence-based MBIs into use in other medical settings. Migraine, the chronic pain condition being used as an example for study, is a significant public health issue. Migraine affects over 30 million Americans, and it is considered to be one of the most disabling conditions. It is responsible for a substantial number of the five million headache visits/year to US EDs. The purpose of this research is to study use of progressive muscle relaxation, a MBI, in patients with migraine who present to the emergency department. During the study, we will use patient feedback to optimize the smartphone application (app) RELAXaHEAD, an app with PMR and a daily headache diary. We will then conduct a feasibility and acceptability study of the RELAX approach (use of RELAXaHEAD and abortive migraine pain medication). The results of this research will inform a future R01 application to conduct a large-scale trial of MBI for migraine patients who present to the ED. The proposed research and training will be conducted at New York University Langone Medical Center's ED. Dr. Minen's mentorship and advisory team includes an interdisciplinary team with experts in MBI and behavioral research, mobile health, headache medicine, emergency medicine, qualitative and mixed methods research, population health, and statistics. The proposed research and training plans will provide a strong foundation for Dr. Minen as an independently funded clinical investigator dedicated to using MBIs alone and in combination with nutraceuticals and medications to improve the care of chronic pain patients in the acute care setting.

项目总结/摘要 这个项目的总体目标是：1）将Mia Minen博士培养成一名疼痛研究者， 和互补的健康与技能进行独立的多学科研究;和2）进行一个 一项评估放松干预治疗偏头痛的可行性和可接受性的临床研究 急诊科（艾德）就诊的患者。米南博士将发展和推进她的知识 通过指导培训，在5个关键领域建立基础、经验和技能：1）身心干预（MBI） 技术; 2）先进的研究方法（在卫生服务、临床试验和移动的卫生战略方面）; 3） 急诊医学疼痛研究方法和负责任的行为; 4）新的研究设计 框架; 5）预防科学，计划干预发展和比较有效性 research.研究培训的长期目标是能够独立开发，评估，完善， 并比较新的和现有的基于证据的MBIs用于不同医学专业的偏头痛患者， 特别关注急诊医学和初级保健环境。此外，培训的目的是 获得先进的技能，单独研究MBIs，并与营养保健品和药物相结合。的 K23申请中提出的研究对于理解基于证据的MBIs如何能够 使急性护理环境中的慢性疼痛患者更容易获得。它有助于建立框架， 将基于证据的MBIs应用于其他医疗环境。偏头痛是一种慢性疼痛， 作为研究的一个例子，是一个重大的公共卫生问题。偏头痛影响着超过3000万美国人， 并且它被认为是最使人丧失能力的条件之一。它负责大量的 每年有500万头痛患者就诊于美国急诊科。本研究的目的是研究渐进肌的使用 放松，MBI，在急诊室就诊的偏头痛患者中。在研究期间，我们 将使用患者反馈来优化智能手机应用程序（应用程序）RELAXaHEAD，这是一款带有PMR和 头痛日记然后，我们会就“放松”方法（使用 RELAXaHEAD和流产偏头痛药物）。这项研究的结果将为未来的R 01提供信息 申请进行大规模的试验MBI偏头痛患者谁提出的ED。 研究和培训将在纽约大学朗格尼医学中心的ED进行。 导师和咨询团队包括一个跨学科的团队，专家在MBI和行为研究， 移动的健康，头痛医学，急诊医学，定性和混合方法研究，人口 健康和统计。拟议的研究和培训计划将为Minen博士提供坚实的基础 作为一名独立资助的临床研究者，致力于单独使用MBIs以及与 营养品和药物，以改善急性护理环境中慢性疼痛患者的护理。

项目成果

Introduction of a smartphone based behavioral intervention for migraine in the emergency department.

• DOI: 10.1016/j.genhosppsych.2020.12.009
• 发表时间: 2021-03
• 期刊: General hospital psychiatry
• 影响因子: 7
• 作者: Minen MT;Friedman BW;Adhikari S;Corner S;Powers SW;Seng EK;Grudzen C;Lipton RB
• 通讯作者: Lipton RB

Heartrate variability biofeedback for migraine using a smartphone application and sensor: A randomized controlled trial.

• DOI: 10.1016/j.genhosppsych.2020.12.008
• 发表时间: 2021-03
• 期刊: General hospital psychiatry
• 影响因子: 7
• 作者: Minen MT;Corner S;Berk T;Levitan V;Friedman S;Adhikari S;Seng EB
• 通讯作者: Seng EB

Underuse of Behavioral Treatments for Headache: a Narrative Review Examining Societal and Cultural Factors.

• DOI: 10.1007/s11606-020-06539-x
• 发表时间: 2021-10
• 期刊: Journal of general internal medicine
• 影响因子: 5.7
• 作者: Langenbahn D;Matsuzawa Y;Lee YSC;Fraser F;Penzien DB;Simon NM;Lipton RB;Minen MT
• 通讯作者: Minen MT

Smartphone based behavioral therapy for pain in multiple sclerosis (MS) patients: A feasibility acceptability randomized controlled study for the treatment of comorbid migraine and ms pain.

• DOI: 10.1016/j.msard.2020.102489
• 发表时间: 2020-11
• 期刊: Multiple sclerosis and related disorders
• 影响因子: 4
• 作者: Minen MT;Schaubhut KB;Morio K
• 通讯作者: Morio K

Addressing the Crisis of Diagnosis and Management of Migraine in Primary Care: A Summary of the American Headache Society FrontLine Primary Care Advisory Board.

• DOI: 10.1111/head.13797
• 发表时间: 2020-05
• 期刊: Headache
• 影响因子: 5
• 作者: Minen MT;Robbins MS;Loder E;Nahas S;Gautreaux J;Litin S;Barch C;Cook C;Smith T;Powers SW;Hasan S;Sbar E;Stika CS;Stone F;Sprouse-Blum A
• 通讯作者: Sprouse-Blum A