Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC)

终止农村社区注射吸毒者的艾滋病毒、丙型肝炎和性病传播以及过量用药（伦理）

• 批准号: 10643614
• 负责人: Wiley Jenkins
• 金额: $ 16.98万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-08-15 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10643614
• 关键词: Address; Administrative Supplement; Area; Awareness; Behavior; Black Populations; Black race; COVID-19 mortality; Cardiovascular Diseases; Caring; Characteristics; Clinical Services; Code; Collaborations; Communicable Diseases; Communities; Community Participation; County; Data; Death Rate; Disease; Disease Outbreaks; Disease Surveillance; Disease model; Distress; Drug usage; Drug user; Emergency Medicine; Enrollment; Ensure; Epidemic; Epidemiology; Event; Gays; Geographic Locations; Goals; HIV; HIV/HCV; HIV/STD; Harm Reduction; Health; Health Disparities Research; Health Services Accessibility; Healthcare; Healthcare Systems; Hepatitis C virus; Heterosexuals; Illinois; Imprisonment; Individual; Infectious Disease Epidemiology; Injecting drug user; Injections; Intervention; Interview; Knowledge; Leadership; Lesbian; Lesbian Gay Bisexual Transgender Queer; Medical; Medical Sociology; Methods; Midwestern United States; Naloxone; Needle Sharing; Needle-Exchange Programs; Neighborhoods; Opiate Addiction; Oral; Outcome; Overdose; Parents; Participant; Pathway interactions; Performance; Persons; Pharmaceutical Preparations; Phase; Poverty; Premature Mortality; Prevention; Process; Public Health; Race; Reach Effectiveness Adoption Implementation and Maintenance; Recording of previous events; Recruitment Activity; Research; Resources; Risk; Route; Rural; Rural Community; Sampling; Services; Social Network; Structural Racism; Substance Use Disorder; Surveys; Syringes; Testing; Trauma; Vision; addiction; base; care systems; cisgender; community engagement; cultural competence; disease transmission; disorder prevention; drug use screening; effectiveness implementation study; effectiveness study; evidence base; experience; gender minority; health care service utilization; health disparity; health seeking behavior; high risk; implementation science; improved; injection drug use; instrument; intergenerational; maternal morbidity; medication-assisted treatment; meetings; member; opioid injection; opioid use; opioid use disorder; overdose prevention; overdose risk; peer; pre-exposure prophylaxis; predictive modeling; prescription opioid; programs; racial minority; recruit; response; rural area; rural dwellers; rural health disparities; rural setting; screening; service organization; sexual minority; social; social culture; social disparities; social media; substance use treatment; success; synthetic opioid; telehealth; transgender; transmission process

ABSTRACT – Modified for administrative supplement, underlined Outbreaks of HIV and HCV in rural areas of the Midwest have been associated with syringe-sharing among partners injecting nonmedical prescription opioids. Illinois ranks as the third highest state in percentage increase in death rates involving synthetic opiates between 2014-2015. The southernmost 16 counties of Illinois comprise the Illinois Delta Region (IDR) and share many of the characteristics of rural areas that have experienced recent HIV epidemics. A deeper understanding of community characteristics, including transitions from oral to injection opioid use, circumstances for high-risk injection practices, impact of race and the effects of structural racism, as well as heterosexism and cisgenderism including accessibility to existing and potential health-related resources will be essential to developing models of disease prevention and treatment. Partnering with state and local public health other state agencies, community-based programs, local coalitions and healthcare systems, we will take a mixed analytical approach using, predictive modeling, GIS analysis, qualitative and survey analysis, network methods, and infectious disease epidemiology to understand geospatial and sociocultural factors impacting health outcomes in people who inject drugs in the IDR. In this supplement we will develop meaningful partnerships with Black and sexual and/or gender minority (SGM) identifying communities in the study area to ensure shared goals, priorities, and processes within the context of drug use and harm reduction research and increase recruitment of Black and SGM identifying individuals into the ETHIC parent study. We will refine current instruments to ensure the optimal exploration and contextualization of potential social, cultural, and medical/structural drug use introduction and continuation pathways, drug types, routes of administration, sharing behaviors, drug use networks, and knowledge and awareness, acceptability, and utilization of harm reduction and addiction treatment with particular focus on salient factors for Black and SGM identifying communities. These data will inform evidence-based, culturally competent and inclusive interventions to strengthen access to disease screening and linkage to care and treatment, expansion of needle exchange and naloxone overdose programs, screening and referral to substance use treatment, and telehealth capacity building for the provision of PrEP, HCV management, and medication-assisted treatment for substance use disorder.

摘要-针对行政补充进行了修改，加下划线 中西部农村地区的艾滋病毒和丙型肝炎病毒的爆发与以下因素有关： 注射非医疗处方阿片类药物的伴侣伊利诺斯州是美国人口比例第三高的州 2014-2015年期间涉及合成阿片类药物的死亡率增加。最南端的16个县 伊利诺伊州包括伊利诺伊州三角洲地区（IDR），并分享许多农村地区的特点， 经历了最近的艾滋病毒流行。更深入地了解社区特征，包括过渡 从口服到注射阿片类药物的使用，高风险注射做法的情况，种族的影响和 结构性种族主义，以及异性恋和顺性别主义，包括现有和潜在的 与卫生有关的资源对于发展疾病预防和治疗模式至关重要。 与州和地方公共卫生机构、其他州机构、基于社区的项目、地方联盟合作 和医疗保健系统，我们将采取混合分析方法，使用，预测建模，GIS分析， 定性和调查分析，网络方法，传染病流行病学了解 地理空间和社会文化因素影响IDR中注射毒品者的健康结果。 在本补充中，我们将与黑人和性和/或性别少数群体建立有意义的伙伴关系 (SGM)确定研究区域内的社区，以确保共同的目标，优先事项，以及 毒品使用和减少危害的研究背景，并增加黑人和SGM的招募， 将个体纳入ETHIC母研究。我们将完善现有的工具，以确保最佳的勘探 潜在的社会、文化和医疗/结构性药物使用的引入和继续 途径、药物类型、给药途径、共享行为、药物使用网络和知识， 对减少伤害和成瘾治疗的认识、可接受性和利用，特别关注 黑人和SGM识别社区的突出因素。这些数据将为基于证据的文化 采取适当和包容性的干预措施，加强获得疾病筛查的机会和与护理的联系， 治疗，扩大针具交换和纳洛酮过量方案，筛查和转诊， 物质使用治疗和远程保健能力建设，以提供PrEP，HCV管理， 药物辅助治疗物质使用障碍。

项目成果

Applying Project ECHO (Extension for Community Health Care Outcomes) to improve addiction care in rural emergency departments.

• DOI: 10.1002/aet2.10804
• 发表时间: 2022-10
• 期刊: AEM EDUCATION AND TRAINING
• 影响因子: 1.8
• 作者: Moore, P. Quincy;Tilmon, Sandra;Chhabra, Neeraj;McCabe, Daniel J.;Aks, Steven E.;Johnson, Daniel;Pho, Mai Tuyet
• 通讯作者: Pho, Mai Tuyet

Cancer Screening among Rural People Who Use Drugs: Colliding Risks and Barriers.

• DOI: 10.3390/ijerph19084555
• 发表时间: 2022-04-10
• 期刊: INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
• 作者: Jenkins, Wiley D.;Rose, Jennifer;Molina, Yamile;Lee, Minjee;Bolinski, Rebecca;Luckey, Georgia;Van Ham, Brent
• 通讯作者: Van Ham, Brent

Sexually Transmitted Infection Epidemiology and Care in Rural Areas: A Narrative Review.

• DOI: 10.1097/olq.0000000000001512
• 发表时间: 2021-12-01
• 期刊: Sexually transmitted diseases
• 影响因子: 3.1
• 作者: Jenkins WD;Williams LD;Pearson WS
• 通讯作者: Pearson WS

Attitudes toward harm reduction and low-threshold healthcare during the COVID-19 pandemic: qualitative interviews with people who use drugs in rural southern Illinois.

对减少伤害的态度和阈值降低期间的医疗保健在Covid-19大流行期间：与在伊利诺伊州南部农村使用毒品的人进行定性访谈。

• DOI: 10.1186/s12954-022-00710-9
• 发表时间: 2022-11-19
• 期刊: HARM REDUCTION JOURNAL
• 影响因子: 4.4
• 作者: Rains, Alex;York, Mary;Bolinski, Rebecca;Ezell, Jerel;Ouellet, Lawrence J.;Jenkins, Wiley D.;Pho, Mai T.
• 通讯作者: Pho, Mai T.