Advancing Couple and Family Alcohol Treatment through Patient-Oriented Research and Mentorship

摘要 酒精滥用对亲密伴侣暴力(IPV)有显著的陡峭影响，IPV是一个持续存在的公众 健康危机影响着大约三分之一的美国人口。创伤后应激障碍(PTSD)是 非常普遍，对酒精滥用有明显的因果影响，是IPV的一个强有力的独立预测因子。 然而，很少有研究考察创伤后应激障碍和酒精滥用对IPV的联合影响。这个问题 这一问题亟待解决，因为缺乏有效预防和治疗与酒精有关的IPV的方法。 将这两个孤立的文学领域结合起来，有助于推动新的、有关创伤的知识的发展 为夫妻提供更强大和更可持续的结果的方式。弗拉纳根博士是理想的候选人 促进这一领域的临床科学发展。根据拟议的中期职业发展奖，她将 通过提高她的口服酒精技能，加速她蓬勃发展的以病人为导向的酒精研究计划 给药，2)强化动态评估，3)心理生理学。她将实现这些目标 通过专家咨询、授课培训和实施拟议的研究项目。她的团队 将研究酒精滥用和创伤后应激障碍对夫妇(N=70)中与酒精相关的IPV的联合影响 无论是在受控的实验室环境中还是在自然主义环境中。这项研究旨在补充 受训者的独立研究兴趣，也将比较不同环境的结果并探索心率 变异性作为假想关系的一种生理机制。无价的保护时间 该K24提供的资源将使弗拉纳根博士能够实现她的主要目标，即扩大她的 在这个关键的职业生涯中期阶段，指导的可用性和技能。她将参与一项教学计划， 专家指导，以扩大她在多样性、公平性和包容性方面的投资，包括指导、领导力和 科学。实现这些协同目标将加快夫妻和家庭酒精研究的科学进程 并为创新的二元疗法奠定了基础。这一奖项还将确保弗拉纳根博士拥有 支持下一代热情的新调查人员，并确保这一至关重要的 酒类领域中代表性不足的领域。

ABSTRACT Alcohol misuse has a salient precipitous effect on intimate partner violence (IPV), which is a persistent public health crisis affecting approximately one-third of the U.S. population. Posttraumatic stress disorder (PTSD) is highly prevalent, has a clear causal effect on alcohol misuse, and it is a robust independent predictor of IPV. However, few studies have examined the combined effects of PTSD and alcohol misuse on IPV. This question is critical to address because effective prevention and treatment approaches for alcohol-related IPV are scant. Integrating these two siloed areas of the literature can help inform the development of novel, trauma-informed modalities for couples to produce stronger and more sustainable outcomes. Dr. Flanagan is the ideal candidate to advance the clinical science in this area. Under the proposed mid-career development award, she will accelerate her thriving patient-oriented alcohol research program by enhancing her skills with 1) oral alcohol administration, 2) intensive ambulatory assessment, and 3) psychophysiology. She will achieve these goals through expert consultation, didactic training, and implementation of the proposed research project. Her team will examine the combined effects of alcohol misuse and PTSD on alcohol-related IPV among couples (N=70) in both a controlled laboratory setting and in naturalistic settings. The study, which was designed to complement mentees’ independent research interests, will also compare outcomes across settings and explore heart rate variability as a physiological mechanism underlying the hypothesized relations. The invaluable protected time and resources provided by this K24 will enable Dr. Flanagan to achieve her primary goal of expanding her mentoring availability and skillset at this pivotal mid-career stage. She will engage a program of didactics and expert coaching to amplify her investment in diversity, equity, and inclusion in mentoring, leadership, and science. Achieving these synergistic objectives will accelerate the science of couple and family alcohol research and set the stage for innovative new dyadic treatments. This award will also ensure that Dr. Flanagan is equipped to support the next generation of enthusiastic new investigators and to ensure the longevity of this vital yet underrepresented area of the alcohol field.