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MObile health interVention to INcrease activity in Heart Failure (MOVIN-HF)

移动健康干预以增加心力衰竭的活动（MOVIN-HF）

基本信息

批准号：
10643400
负责人：
Jessica Rachel Golbus
金额：
$ 18.24万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-04-10 至 2028-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10643400
关键词：
Address Adult Affect American Behavioral Biological Biological Factors Cardiac rehabilitation Cardiovascular Diseases Cardiovascular system Cellular Phone Chronic Chronic Disease Clinical Clinical Trials Complement Data Deterioration Development Development Plans Disease Disease Management Doctor of Philosophy EFRAC Ecological momentary assessment Educational workshop Eligibility Determination Enrollment Ensure Environment Feedback Frequencies General Population Geography Goals Health Technology Heart Transplantation Heart failure Home Hospitalization Interdisciplinary Study Intervention K-Series Research Career Programs Learning Longitudinal cohort study Medicare Mentors Mentorship Methods Michigan Moods Morbidity - disease rate Motivation Notification Participant Patient Participation Patient-Focused Outcomes Patients Phenotype Physical Function Physical activity Population Predictive Factor Process Psychosocial Factor Public Health Quality of life Questionnaires Randomized Research Research Activity Research Design Resources Self Determination Self Management Statistical Methods Structure Surveys Symptoms Technology Time Time Factors Training Training Activity Universities Variant Vision Weather Work adaptive intervention behavioral health beneficiary career development clinical encounter cohort community based participatory research comorbidity design exercise capacity improved improved outcome innovation lifestyle intervention mHealth mobile computing mortality personalized care physical inactivity preservation primary outcome programs psychosocial racial disparity randomized trial recruit research clinical testing sex skills smart watch sociodemographic factors theories treatment as usual user centered design wearable device

项目摘要

PROJECT SUMMARY/ABSTRACT Candidate: Jessica Golbus, MD, MS is a heart failure (HF) and transplant cardiologist at the University of Michigan. Her long-term goal is to use mobile health (mHealth) technologies to deliver personalized, lifestyle interventions to patients with chronic cardiovascular diseases (CVD) to support them in longitudinal disease self-management. This proposal builds on Dr. Golbus’s prior mHealth research, providing her with protected time to train in behavioral health theory, user-centered design, and mHealth study design. Environment and Career Development Plan: The training and research activities will be conducted at the University of Michigan, a world-class scientific environment that promotes multi-disciplinary collaboration. The research will be completed under the mentorship of primary mentor Brahmajee Nallamothu, MD, MPH and co- mentors Kenneth Resnicow, PhD and Predrag Klasnja, PhD who are leaders in cardiovascular and mHealth research, behavioral health theory, and user-centered design, respectively. This will be complemented by a scientific advisory board with expertise in clinical trials, community-based participatory research, statistical methods for mHealth studies, and HF. The 5-year plan includes didactic coursework, mentored research, and professional development activities, with defined milestones to ensure successful transition to independence. Background: Through this career development award, Dr. Golbus proposes to address the important clinical problem of physical inactivity in HF patients. While increased physical activity reduces hospitalizations and improves quality-of-life in this population, many HF patients participate insufficiently in physical activity. Existing strategies to increase physical activity levels have not accounted for the unique needs of HF patients, such as time-varying biological and psychosocial factors impacting activity levels, or are resource-intensive. There is thus a need for innovative strategies to increase physical activity for HF patients. Research: The overarching goals of this proposal are two-fold. First, it will characterize real-time factors impacting physical activity participation in a diverse cohort of HF patients using mHealth technologies, which will then be used to design and pilot a physical activity just-in-time adaptive intervention. The proposal’s 3 Specific Aims are as follows. Aim 1: Characterize real-time factors impacting physical activity in HF patients using mHealth technology (training aim: behavioral health theory). Aim 2: Employ user-centered design methods to adapt an existing mHealth intervention for HF (training aim: user-centered design). Aim 3: Conduct a pilot of a physical activity mHealth intervention for patients with HF targeting barriers and facilitators to physical activity (training aim: mHealth study design). The second goal of this proposal is to establish Dr. Golbus as a leader in mHealth interventions for CVD management and provide her the skills necessary to combine behavioral theory with emerging mHealth technologies to promote personalized care for HF patients.

项目概要/摘要候选人：杰西卡·戈尔布斯 (Jessica Golbus)，医学博士、理学硕士，是伦敦大学的一名心力衰竭 (HF) 和移植心脏病专家密歇根州。她的长期目标是利用移动健康 (mHealth) 技术提供个性化的生活方式对慢性心血管疾病 (CVD) 患者进行干预以支持他们的纵向疾病自我管理。该提案建立在 Golbus 博士之前的移动医疗研究的基础上，为她提供了受保护的是时候进行行为健康理论、以用户为中心的设计和移动医疗研究设计方面的培训了。环境和职业发展计划：培训和研究活动将在密歇根大学拥有世界一流的科学环境，促进多学科合作。这研究将在主要导师 Brahmajee Nallamothu（医学博士、公共卫生硕士）和合作者的指导下完成导师 Kenneth Resnicow 博士和 Predrag Klasnja 博士，他们是心血管和移动健康领域的领导者分别是研究、行为健康理论和以用户为中心的设计。这将得到补充科学顾问委员会拥有临床试验、社区参与性研究、统计方面的专业知识移动健康研究方法和 HF。五年计划包括教学课程、指导研究和专业发展活动，具有明确的里程碑，以确保成功过渡到独立。背景：通过这个职业发展奖，Golbus 博士建议解决重要的临床问题心力衰竭患者缺乏身体活动的问题。虽然增加体力活动可以减少住院次数虽然改善了这一人群的生活质量，但许多心力衰竭患者的体力活动参与不足。现有的提高体力活动水平的策略并未考虑到心力衰竭患者的独特需求，例如影响活动水平的时变生物和心理社会因素，或者是资源密集型的。因此，需要创新策略来增加心力衰竭患者的体力活动。研究：该提案的总体目标有两个。首先，它将表征实时因素使用移动医疗技术影响不同心力衰竭患者群体的身体活动参与情况，然后将用于设计和试点身体活动适时适应性干预。提案3 具体目标如下。目标 1：描述影响心力衰竭患者体力活动的实时因素使用移动健康技术（培训目标：行为健康理论）。目标 2：采用以用户为中心的设计调整现有心力衰竭移动医疗干预的方法（培训目标：以用户为中心的设计）。目标 3：行为针对心力衰竭患者的体力活动移动健康干预试点，针对障碍和促进因素体力活动（培训目标：移动健康研究设计）。该提案的第二个目标是建立博士。 Golbus 作为 CVD 管理移动医疗干预领域的领导者，为她提供了必要的技能将行为理论与新兴的移动医疗技术相结合，促进心力衰竭患者的个性化护理。