MObile health interVention to INcrease activity in Heart Failure (MOVIN-HF)

移动健康干预以增加心力衰竭的活动（MOVIN-HF）

• 批准号: 10643400
• 负责人: Jessica Rachel Golbus
• 金额: $ 18.24万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-04-10 至 2028-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10643400
• 关键词: Address; Adult; Affect; American; Behavioral; Biological; Biological Factors; Cardiac rehabilitation; Cardiovascular Diseases; Cardiovascular system; Cellular Phone; Chronic; Chronic Disease; Clinical; Clinical Trials; Complement; Data; Deterioration; Development; Development Plans; Disease; Disease Management; Doctor of Philosophy; EFRAC; Ecological momentary assessment; Educational workshop; Eligibility Determination; Enrollment; Ensure; Environment; Feedback; Frequencies; General Population; Geography; Goals; Health Technology; Heart Transplantation; Heart failure; Home; Hospitalization; Interdisciplinary Study; Intervention; K-Series Research Career Programs; Learning; Longitudinal cohort study; Medicare; Mentors; Mentorship; Methods; Michigan; Moods; Morbidity - disease rate; Motivation; Notification; Participant; Patient Participation; Patient-Focused Outcomes; Patients; Phenotype; Physical Function; Physical activity; Population; Predictive Factor; Process; Psychosocial Factor; Public Health; Quality of life; Questionnaires; Randomized; Research; Research Activity; Research Design; Resources; Self Determination; Self Management; Statistical Methods; Structure; Surveys; Symptoms; Technology; Time; Time Factors; Training; Training Activity; Universities; Variant; Vision; Weather; Work; adaptive intervention; behavioral health; beneficiary; career development; clinical encounter; cohort; community based participatory research; comorbidity; design; exercise capacity; improved; improved outcome; innovation; lifestyle intervention; mHealth; mobile computing; mortality; personalized care; physical inactivity; preservation; primary outcome; programs; psychosocial; racial disparity; randomized trial; recruit; research clinical testing; sex; skills; smart watch; sociodemographic factors; theories; treatment as usual; user centered design; wearable device

PROJECT SUMMARY/ABSTRACT Candidate: Jessica Golbus, MD, MS is a heart failure (HF) and transplant cardiologist at the University of Michigan. Her long-term goal is to use mobile health (mHealth) technologies to deliver personalized, lifestyle interventions to patients with chronic cardiovascular diseases (CVD) to support them in longitudinal disease self-management. This proposal builds on Dr. Golbus’s prior mHealth research, providing her with protected time to train in behavioral health theory, user-centered design, and mHealth study design. Environment and Career Development Plan: The training and research activities will be conducted at the University of Michigan, a world-class scientific environment that promotes multi-disciplinary collaboration. The research will be completed under the mentorship of primary mentor Brahmajee Nallamothu, MD, MPH and co- mentors Kenneth Resnicow, PhD and Predrag Klasnja, PhD who are leaders in cardiovascular and mHealth research, behavioral health theory, and user-centered design, respectively. This will be complemented by a scientific advisory board with expertise in clinical trials, community-based participatory research, statistical methods for mHealth studies, and HF. The 5-year plan includes didactic coursework, mentored research, and professional development activities, with defined milestones to ensure successful transition to independence. Background: Through this career development award, Dr. Golbus proposes to address the important clinical problem of physical inactivity in HF patients. While increased physical activity reduces hospitalizations and improves quality-of-life in this population, many HF patients participate insufficiently in physical activity. Existing strategies to increase physical activity levels have not accounted for the unique needs of HF patients, such as time-varying biological and psychosocial factors impacting activity levels, or are resource-intensive. There is thus a need for innovative strategies to increase physical activity for HF patients. Research: The overarching goals of this proposal are two-fold. First, it will characterize real-time factors impacting physical activity participation in a diverse cohort of HF patients using mHealth technologies, which will then be used to design and pilot a physical activity just-in-time adaptive intervention. The proposal’s 3 Specific Aims are as follows. Aim 1: Characterize real-time factors impacting physical activity in HF patients using mHealth technology (training aim: behavioral health theory). Aim 2: Employ user-centered design methods to adapt an existing mHealth intervention for HF (training aim: user-centered design). Aim 3: Conduct a pilot of a physical activity mHealth intervention for patients with HF targeting barriers and facilitators to physical activity (training aim: mHealth study design). The second goal of this proposal is to establish Dr. Golbus as a leader in mHealth interventions for CVD management and provide her the skills necessary to combine behavioral theory with emerging mHealth technologies to promote personalized care for HF patients.

项目总结/摘要 候选人：Jessica Golbus，医学博士，MS，是一名心力衰竭（HF）和移植心脏病专家，来自美国宾夕法尼亚大学。 密歇根她的长期目标是利用移动的健康（mHealth）技术， 慢性心血管疾病（CVD）患者的干预措施，以支持他们在纵向疾病 自我管理该提案建立在Golbus博士之前的移动健康研究基础上，为她提供了受保护的 时间来培训行为健康理论，以用户为中心的设计，和mHealth研究设计。 环境和职业发展计划：培训和研究活动将在 密歇根大学，世界一流的科学环境，促进多学科合作。的 研究将在主要导师Brahmajee Nallamothu，MD，MPH和共同的指导下完成， 导师Kenneth Resnicow博士和Predrag Klasnja博士是心血管和移动健康领域的领导者 研究，行为健康理论和以用户为中心的设计，分别。这将由一个 具有临床试验、社区参与性研究、统计、 mHealth研究的方法，以及HF。5年计划包括教学课程，指导研究， 专业发展活动，确定里程碑，以确保成功过渡到独立。 背景：通过这个职业发展奖，Golbus博士建议解决重要的临床问题。 HF患者缺乏体力活动的问题。虽然增加身体活动减少了住院治疗， 改善该人群的生活质量，但许多HF患者参与体力活动不足。 现有的增加体力活动水平的策略没有考虑到HF患者的独特需求， 例如影响活动水平的时变生物和心理社会因素，或资源密集型。 因此，需要创新的策略来增加HF患者的体力活动。 研究：本提案的总体目标是双重的。首先，它将表征实时因素 使用mHealth技术影响不同HF患者队列的身体活动参与， 然后将用于设计和试点的身体活动及时适应性干预。提案是3 具体目标如下。目的1：表征影响HF患者体力活动的实时因素 使用mHealth技术（培训目标：行为健康理论）。目标2：采用以用户为中心的设计 方法，以适应现有的移动健康干预HF（培训目标：以用户为中心的设计）。目标3：行为 一项针对HF患者的身体活动mHealth干预试点，目标是障碍和促进者， 体力活动（培训目标：移动健康研究设计）。本提案的第二个目标是建立博士。 Golbus作为CVD管理mHealth干预措施的领导者，并为她提供必要的技能， 将联合收割机行为理论与新兴的移动健康技术相结合，以促进HF患者的个性化护理。