Impacts of Early Life Food Insecurity on Child Obesity and Cognitive Development Trajectories

生命早期粮食不安全对儿童肥胖和认知发展轨迹的影响

• 批准号: 10534336
• 负责人: Eliza W. Kinsey
• 金额: $ 24.88万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10534336
• 关键词: Adolescence; Adolescent; Adolescent obesity; Adult; Age; Anxiety; Attention; Award; Birth; Body Composition; Body mass index; Brain; Child; Child Rearing; Childhood; Cognition; Cognitive; Cohort Studies; Collection; Complex; Data; Data Analyses; Data Collection; Development; Diagnostic tests; Emotional; Enrollment; Environment; Environmental Health; Epidemiologic Methods; Epidemiology; Family; Food; Food Assistance Programs; Generations; Goals; Gold; Growth; Growth and Development function; Health Food; Health Policy; Health Status; Household; Intervention; Knowledge; Life; Link; Liquid substance; Long-Term Effects; Longitudinal cohort study; Low income; Magnetic Resonance Imaging; Measurement; Measures; Mentorship; Methods; Mothers; Motor; Newborn Infant; Obesity; Pathway interactions; Phase; Policies; Pregnancy; Psyche structure; Public Health; Public Health Schools; Research; Role; S-nitro-N-acetylpenicillamine; Scientist; Screening procedure; Social Policies; Special Supplemental Nutrition Program for Women, Infants, and Children; Stress; Supervision; Surveys; System; Teenagers; Testing; Time; Training; Translations; Urban Health; Woman; Work; Youth; abdominal fat; active lifestyle; career; career development; cognitive control; cognitive development; cognitive function; cognitive load; cognitive testing; cohort; community partnership; design; diagnostic screening; early childhood; electric impedance; epidemiology study; evidence based guidelines; experience; follow-up; food insecurity; food marketing; food security; food standard; health of the mother; healthy lifestyle; indexing; insight; maternal obesity; middle childhood; novel; nutrition; obesity development; obesity in children; postnatal; prenatal; psychosocial; skills; young adult

PROJECT SUMMARY/ABSTRACT Food insecurity is a significant public health concern and is defined as limited or uncertain access to enough food for an active and healthy lifestyle. Food insecurity impacts 15.7% of households with children in the U.S., but its effects on child growth and developmental trajectories are not well documented. In this K99/R00 Pathway to Independence Award project, I propose research aims to better understand the impact of early life food insecurity on child growth and development. I will utilize data from two ongoing birth cohort studies at the Columbia Center for Children's Environmental Health (CCCEH) to assess the effects of food insecurity during pregnancy and intermittent and persistent food insecurity during early childhood on 1) maternal obesity and cognitive function, and 2) childhood growth and cognitive development trajectories from early childhood to age 18. This will be the first study to simultaneously examine the role of food insecurity trajectories in child and adolescent cognitive development and obesity. This research will combine cutting edge body composition measurement, cognitive assessment and epidemiologic methods and will contribute important substantive knowledge on the food insecurity-obesity and the food insecurity-cognitive function associations within children and adolescents. This work will also provide novel insight to inform evidence-based recommendations and interventions around child and adolescent obesity. During the K99 phase, my work will be situated within the top- tier research environments of Columbia's Mailman School of Public Health, the CCCEH and the NY Obesity Research Center, all of which have a strong focus on policy translation and community partnerships. Situating my K99/R00 work in a research environment focused on policy translation and analysis will provide me with experience and training in how research findings and data can contribute to policy debates and to the generation of new data driven policies. The training goals of this K99/R00 are to become skilled in complex longitudinal data analyses, body composition assessment in children and adolescents using bio-impedance and magnetic resonance imaging, child cognitive development assessment using diagnostic tests, and collection and analysis of quantitative data within a birth cohort. As part of the R00 phase, I will gain field experience in collecting anthropometric and cognitive data from children. This work is a logical extension of my prior and ongoing research in obesity, nutrition and food insecurity, and will fill gaps in training that I need to launch my career as an independent scientist working at the intersection of epidemiology, urban health and social policy.

项目总结/摘要 粮食不安全是一个重大的公共卫生问题，其定义是获得足够粮食的机会有限或不确定。 积极健康的生活方式的食物。粮食不安全影响了美国15.7%的有孩子的家庭， 但它对儿童生长和发育轨迹的影响并没有很好的记录。在K99/R 00通路中， 对于独立奖项目，我建议研究旨在更好地了解早期食物的影响 不安全对儿童成长和发展的影响。我将利用两个正在进行的出生队列研究的数据， 哥伦比亚儿童环境健康中心（CCCEH）评估了粮食不安全的影响， 怀孕以及幼儿期间歇性和持续性的粮食不安全对1）产妇肥胖和 认知功能，以及2）从幼儿期到老年的儿童生长和认知发展轨迹 18.这将是第一项同时研究粮食不安全轨迹在儿童和青少年中的作用的研究。 青少年认知发展和肥胖。本研究将联合收割机切削刃体组成 测量，认知评估和流行病学方法，并将有助于重要的实质性 儿童对食物不安全-肥胖和食物不安全-认知功能关系的认识 和青少年。这项工作还将提供新的见解，为基于证据的建议提供信息， 针对儿童和青少年肥胖的干预措施。在K99阶段，我的工作将位于顶部- 哥伦比亚梅尔曼公共卫生学院、CCCEH和纽约肥胖研究所的分层研究环境 研究中心，所有这些都非常注重政策翻译和社区伙伴关系。构境 我的K99/R 00工作在一个专注于政策翻译和分析的研究环境将为我提供 在研究结果和数据如何能够促进政策辩论和产生 数据驱动的新政策。本K99/R 00的培训目标是熟练掌握复杂的纵向数据 分析，使用生物阻抗和磁场对儿童和青少年进行身体成分评估 共振成像，使用诊断测试进行儿童认知发展评估，以及收集和分析 出生队列中的定量数据。作为R 00阶段的一部分，我将获得实地收集经验 人体测量和认知数据。这项工作是我先前和正在进行的工作的逻辑延伸 研究肥胖，营养和粮食不安全，并将填补培训的空白，我需要启动我的职业生涯， 他是一位独立的科学家，从事流行病学、城市卫生和社会政策的交叉研究。