Examining the long-term relationship between sleep and diet

检查睡眠和饮食之间的长期关系

• 批准号: 10536478
• 负责人: Kaitlin Storck Potts
• 金额: $ 1.35万
• 依托单位: TULANE UNIVERSITY OF LOUISIANA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-01-01 至 2022-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10536478
• 关键词: Accounting; Address; Adult; Affect; African American population; Alabama; American; Area; Body mass index; Cardiometabolic Disease; Cardiovascular Diseases; Cause of Death; Characteristics; Childhood; Chronic; Chronic Disease; Cohort Studies; Communities; Complex; Data; Development; Diabetes Mellitus; Diet; Dietary intake; Disease; Drowsiness; Epidemiology; Faculty; Food; Foundations; Future; Goals; Health; Heart; Hypertension; Intervention; Knowledge; Lead; Life; Life Cycle Stages; Life Style; Link; Longitudinal Studies; Louisiana; Mentors; Methods; Mississippi; Modification; Morbidity - disease rate; Nutritional; Obesity; Outcome; Performance; Personal Satisfaction; Persons; Physical activity; Play; Population; Population Heterogeneity; Prevalence; Race; Reduce health disparities; Research; Research Personnel; Research Project Grants; Research Training; Risk; Risk Factors; Role; Rural Community; Sex Differences; Sleep; Sleep Apnea Syndromes; Sleep Deprivation; Sleep Disorders; Sleep disturbances; Socioeconomic Status; Stratification; Techniques; Time; Unhealthy Diet; United States; United States National Institutes of Health; Weight Gain; Woman; Work; biological sex; biracial; black women; cardiometabolic risk; cardiovascular risk factor; career; cohort; design; dietary; disease disparity; experience; experimental study; falls; health disparity; healthy weight; improved; lipid disorder; low socioeconomic status; meetings; men; middle age; mortality; obesity prevention; prevent; programs; prospective; racial difference; sex; skills; sleep behavior; sleep health; sleep pattern; sleep quality; young adult

PROJECT SUMMARY/ABSTRACT Poor diet quality contributes to the excess burden of cardiometabolic diseases among U.S. adults. Short sleep and poor quality sleep are increasing and have been linked to obesity and cardiometabolic diseases. There is evidence that both diet and reduced sleep duration and quality impact African Americans and those with low socio-economic status more so than other groups, and that these differences may contribute to health disparities in cardiometabolic diseases. Specific aspects of diet have been linked to sleep outcomes in the short term and similarly, experimental studies of sleep restriction have found short sleep can lead to poor dietary choices and weight gain, demonstrating the bi-directionality of the diet and sleep relationship in the near term. However, the inter-relationship between diet and sleep is complex and has rarely been studied in the long-term nor with aspects of sleep beyond duration including quality, regularity, disturbance, and sleepiness. Therefor, this study will address this knowledge gap by examining the long-term relationships between diet and sleep in the Bogalusa Heart Study cohort of 1250 men and women from a biracial community in Louisiana that have been prospectively followed for over 40 years, since childhood. The first aim of the research is to prospectively examine the effect of multiple aspects of sleep (e.g. duration, quality, sleepiness) on dietary intake in midlife among the Bogalusa Heart Study cohort. The second aim of the research is to prospectively examine the effect of dietary intake in young adulthood on long-term sleep outcomes later in life including sleep duration, quality, regularity, disturbance, and sleepiness accounting for body mass index, risk for sleep disordered breathing, and physical activity. The third aim is to determine if differences by race, biologic sex, and socioeconomic status exist in the relationships between diet and sleep over the life course. The long-term goal in pursuing this research project and training plan is to produce an independent investigator in nutritional and lifestyle epidemiology, well prepared to pursue a research career that alleviates the burden of disparity in obesity and obesity-related morbidity and mortality for people in the Gulf South Region of the United States. This will be achieved by meeting the overall objective of this project, implementing a tailored, individualized, mentored research training experience that contributes to closing a long-standing knowledge gap in the long-term relationship between diet and sleep. The impact of this work will be to produce a future leader in nutritional and lifestyle epidemiology. The knowledge gained will allow for the development of appropriately timed and targeted intervention opportunities to maintain healthy weight and sleep patterns that prevent chronic cardiometabolic diseases among diverse populations in the U.S. while reducing health disparities. The Bogalusa Heart Study cohort is a unique and ideal setting in which to perform this research.

项目摘要/摘要 糟糕的饮食质量是美国成年人心脏代谢性疾病负担过重的原因之一。短时睡眠 睡眠质量差的人越来越多，并与肥胖和心脏代谢性疾病有关。的确有 有证据表明，节食、睡眠时间减少和睡眠质量都会影响非裔美国人和低收入人群 社会经济地位比其他群体更高，这些差异可能有助于健康 心脏代谢性疾病的差异。饮食的特定方面与睡眠结果有关 同样，短期的睡眠限制实验研究发现，睡眠不足会导致睡眠不佳 饮食选择和体重增加，证明了饮食和睡眠关系的双向在 近期。然而，饮食和睡眠之间的相互关系是复杂的，很少有人在 睡眠质量、规律性、干扰和睡眠时间以外的长期睡眠问题 困倦。因此，本研究将通过考察长期关系来解决这一知识鸿沟 博加卢萨心脏研究对来自混血社区的1250名男女进行的饮食和睡眠之间的关系研究 在路易斯安那州，从孩提时代起，人们就对其进行了40多年的前瞻性跟踪。的第一个目标是 研究是前瞻性地检查睡眠的多个方面的影响(例如持续时间、质量、困倦) 博加卢萨心脏研究队列中的中年饮食摄入量。研究的第二个目的是 前瞻性研究青年时期饮食摄入量对晚年长期睡眠结果的影响 包括睡眠时间、质量、规律性、扰乱和嗜睡，考虑到身体质量指数、风险 用于睡眠、呼吸紊乱和体力活动。第三个目标是确定是否存在种族差异， 在生命过程中，饮食和睡眠之间的关系中存在着生物性行为和社会经济地位。 进行这一研究项目和培训计划的长期目标是产生一名独立的调查员 在营养和生活方式流行病学方面，充分准备从事减轻以下方面负担的研究事业 肥胖症和肥胖相关发病率和死亡率在海湾南部地区的差异 美国。这将通过满足该项目的总体目标、实施量身定制的、 个性化、有指导的研究培训体验，有助于结束长期积累的知识 饮食和睡眠之间的长期关系存在差距。这项工作的影响将是产生一个未来 在营养和生活方式流行病学方面处于领先地位。所获得的知识将有助于发展 适当的时机和针对性的干预机会，以保持健康的体重和睡眠模式， 在美国不同人群中预防慢性心脏代谢性疾病，同时降低健康 差距。博加卢萨心脏研究队列是进行这项研究的独特和理想的环境。