RR&D Research Career Scientist Award Application

RR

基本信息

  • 批准号:
    10533303
  • 负责人:
  • 金额:
    --
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2020
  • 资助国家:
    美国
  • 起止时间:
    2020-01-01 至 2024-12-31
  • 项目状态:
    已结题

项目摘要

Abstract Robert L. Mauck, PhD is a Research Health Scientist and Co-Director of the Translational Musculoskeletal Research Center at the Corporal Michael J. Crescenz VA Medical Center in Philadelphia. He is also the Mary Black Ralston Professor of Education and Research in Orthopaedic Surgery and Professor of Bioengineering at the University of Pennsylvania, and the Director of the McKay Orthopaedic Research Laboratory. At Penn, Dr. Mauck also serves as the Co-Director of the Program in Musculoskeletal Regeneration in the Institute for Regenerative Medicine (IRM), is the Director of the Biomechanics Core of the Penn Center for Musculoskeletal Disorders (PCMD), and is a founding member of the Center for Engineering Mechanobiology (CEMB). Dr. Mauck’s research program is focused on the engineering and mechanobiology of musculoskeletal tissues, with a particular interest in restoring articular cartilage, the knee meniscus, and the intervertebral disc. Dr. Mauck’s team uses mechanical and molecular analyses to explore native tissue structure function relationships, and employs this information to enhance the functional properties of engineered constructs through focused technology development. His work explores progenitor cell function and efficacy in a variety of biomaterial contexts and across multiple length scales, from subcellular biophysical properties to translation of engineered constructs in large animal models and humans. The goal of his research program is to develop and deploy novel regenerative therapies to improve musculoskeletal health in Veterans and the population as a whole. Dr. Mauck is supported by the Department of Veterans Affairs, the National Institutes of Health, the National Science Foundation, and several foundations and private organizations. He is an active member of the American Society for Mechanical Engineers (ASME), the Orthopaedic Research Society (ORS), the Tissue Engineering and Regenerative Medicine International Society (TERMIS), the Biomedical Engineering Society (BMES), and the International Cartilage Repair Society (ICRS). Dr. Mauck is the co-Editor-in-Chief of the Journal of Orthopaedic Research Spine and serves on the editorial board of the Journal of Orthopaedic Research, the Journal of the Mechanical Behavior of Biomedical Materials, and the Journal of Experimental Orthopaedics. He has published >190 manuscripts (cited >10400 times), >300 abstracts, and >12 book chapters. Dr. Mauck has been recognized for his contributions to the field with the ISSLS Prize in Biomechanics (2008), the YC Fung Young Investigator Award from the ASME (2009), the BMES-CMBE ‘Rising Star’ Award (2011), the Penn Medicine Montague Research Prize (2013), election to the College of Fellows of the American Institute for Medical and Biological Engineering (2014), the Kappa Delta Young Investigator Award from the American Academy of Orthopaedic Surgeons (2015), the Berton Rahn Research Award from the AO Foundation (2017), and was inducted as a Fellow of International Orthopaedic Research (FIOR) of the International Combined Orthopaedic Research Societies (ICORS) College of Fellows (2019). He was also recently selected as the ‘Research Scientist of the Year’ at the CMC VAMC (2019).
摘要 Robert L. Mauck博士是一位研究健康科学家,也是翻译 迈克尔·J·克雷森兹下士退伍军人医疗中心的肌肉骨骼研究中心, 费城他也是玛丽布莱克罗尔斯顿教授的教育和研究骨科 宾夕法尼亚大学外科和生物工程教授,以及 麦凯骨科研究实验室。在宾夕法尼亚大学,Mauck博士还担任 再生医学研究所(Institute for Regenerative Medicine,简称RMD)的肌肉骨骼再生项目是 宾夕法尼亚肌肉骨骼疾病中心(PCMD)生物力学核心主任, 工程机械生物学中心(CEMB)的创始成员。 博士Mauck的研究项目主要集中在肌肉骨骼的工程和机械生物学 组织,特别关注恢复关节软骨、膝关节半月板和 椎间盘Mauck博士的团队使用机械和分子分析来探索天然的 组织结构功能关系,并利用这些信息来增强功能 通过集中的技术开发,提高工程结构的性能。他的作品探索了 祖细胞在各种生物材料环境中的功能和功效, 从亚细胞生物物理特性到大型动物中工程构建体的翻译 模型和人类他的研究计划的目标是开发和部署新的再生 治疗,以改善退伍军人和整个人口的肌肉骨骼健康。 博士Mauck得到了退伍军人事务部,国立卫生研究院, 国家科学基金会,以及一些基金会和私人组织。他是一个活跃 美国机械工程师协会(ASME)会员, 国际组织工程与再生医学学会(Tissue Engineering and Regenerative Medicine International Society,TERMIS) 生物医学工程学会(BMES)和国际腕关节修复学会(ICRS)。 博士Mauck是《脊柱矫形研究杂志》的联合主编, 《矫形研究杂志》(Journal of Orthopathy Research)、《矫形外科学的机械行为杂志》(Journal of the Mechanical Behavior of the Orthopathy)、《矫形外科学的机械行为杂志》(Journal of the Mechanical Behavior of the Orthopathy)、《矫形外科学的机械行为杂志》(Journal of the Mechanical Behavior of the Orthopathy)的编委会。 生物医学材料和实验骨科杂志。已出版>190 手稿(引用>10400次),>300篇摘要和>12本书的章节。 博士Mauck因其在该领域的贡献而获得ISSLS生物力学奖 (2008)、ASME冯耀宗青年研究员奖(2009)、BMES-CMBE“明日之星星星” 奖(2011年),宾夕法尼亚大学医学蒙塔古研究奖(2013年),当选为学院 美国医学和生物工程研究所院士(2014年),卡帕三角洲 美国骨科医师学会青年研究者奖(2015年),Berton 2017年获得AO基金会的Rahn研究奖,并被选为国际研究员 国际矫形联合研究会矫形研究 (ICORS)研究员学院(2019)。他最近还被选为“研究科学家的 2019年在CMC VAMC举行。

项目成果

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Robert L Mauck其他文献

Robert L Mauck的其他文献

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{{ truncateString('Robert L Mauck', 18)}}的其他基金

Training Program in Musculoskeletal Research
肌肉骨骼研究培训计划
  • 批准号:
    10861378
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
Activation of endogenous progenitors via a nanoparticle-conjugated fibrous system to enhance meniscus repair
通过纳米颗粒共轭纤维系统激活内源祖细胞以增强半月板修复
  • 批准号:
    10607306
  • 财政年份:
    2023
  • 资助金额:
    --
  • 项目类别:
Knee Joint Resurfacing with Anatomic Tissue Engineered Osteochondral Implants
使用解剖组织工程骨软骨植入物进行膝关节表面置换
  • 批准号:
    10704534
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Knee Joint Resurfacing with Anatomic Tissue Engineered Osteochondral Implants
使用解剖组织工程骨软骨植入物进行膝关节表面置换
  • 批准号:
    10248368
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Hydrogel Delivery of Extracellular Vesicles to Treat Osteoarthritis
水凝胶递送细胞外囊泡治疗骨关节炎
  • 批准号:
    10631851
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
RR&D Research Career Scientist Award Application
RR
  • 批准号:
    10311108
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Hydrogel Delivery of Extracellular Vesicles to Treat Osteoarthritis
水凝胶递送细胞外囊泡治疗骨关节炎
  • 批准号:
    10176189
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Knee Joint Resurfacing with Anatomic Tissue Engineered Osteochondral Implants
使用解剖组织工程骨软骨植入物进行膝关节表面置换
  • 批准号:
    10454898
  • 财政年份:
    2020
  • 资助金额:
    --
  • 项目类别:
Mechanobiology of Progenitor Cells in Heterotopic Ossification
异位骨化中祖细胞的力学生物学
  • 批准号:
    10401824
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:
Mechanobiology of Progenitor Cells in Heterotopic Ossification
异位骨化中祖细胞的力学生物学
  • 批准号:
    9926811
  • 财政年份:
    2018
  • 资助金额:
    --
  • 项目类别:

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