Training Program for Innovative Engineering Research in Surgery and Intervention

外科和介入创新工程研究培训计划

• 批准号: 10663309
• 负责人: Michael Ian Miga
• 金额: $ 20.58万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2026-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10663309
• 关键词: Engineering; Intervention; Operative Surgical Procedures; Research; Training Programs; innovation

Training Program Summary Over the past several decades, dramatic breakthroughs in biomedical science have been witnessed within laboratory research. The ability to translate those discoveries as well as to make new discoveries within human investigations has been a challenge and has been often characterized as the bottleneck of clinical research. Added to this context has been the dramatic changes to healthcare organizational environments, constraints on delivery, efficiency, and reimbursements to include major structural changes to the investment in healthcare research, both federally, and industrially. Lastly, as a result of dramatic systemic changes in healthcare funding structure, the impact on higher educational graduates' careers, specifically doctoral graduates, has been quite profound. Within that changing dynamic landscape, we hypothesize that the fundamental bottlenecks associated with clinical translational research can be dramatically loosened with the training of engineers intimately familiar with human treatment and trained in the inception of novel technology-based platforms. We further hypothesize that continued scientific discoveries within the human environment as well as novel treatment approaches are highly dependent on these technology-based platforms. The purpose of this training program is to create a new cadre of researchers capable of creating, developing, implementing, clinically evaluating, and translating methods, devices, algorithms, and systems designed with a clear focus at one particular application of medicine, namely, to facilitate surgical/interventional processes and their outcomes. Thematically, our trainees and training program will have a central focus – innovative platform technologies for treatment and discovery. While this training program addresses pressing problems in biomedical research, namely the translation and facilitation of human investigative systems, the program also speaks to improving higher education career trajectories by providing a novel professional development atmosphere. Briefly described, the training program is a year 2, 3 program that centers on a novel dual-course clinical immersion sequence (a first course that is a context heavy experience with physicians introducing their specialty and clinical realities, and a second course that is an intensively immersive environment with students embedded within the clinical team). In both courses, students are required to engage in expository writing associated with disease and therapeutic analysis, provocative question solutions, clinical outcome analysis and reviews, and mock grant applications. This framework supports a unique educational paradigm brought to engineering education. Apart from this sequence, training continues with addition course work among areas associated with surgical/interventional guidance and delivery, interventional imaging, medical image processing and analysis, robotics and medical device design, modeling & simulation, interventional therapeutics, and new to this cycle, interventional and surgical data science. This all takes place in one of the most strategically collocated environments for engineering, surgery, and intervention in the world. This is a Training Program for Innovative Engineering Research in Surgery and Intervention.

培训计划摘要 在过去的几十年里，生物医学科学取得了巨大的突破 实验室研究。翻译这些发现的能力以及在人类内部进行新发现的能力 调查一直是一个挑战，并经常被描述为临床研究的瓶颈。 在此背景下，医疗保健组织环境发生了戏剧性的变化，限制了 交付、效率和报销，包括医疗保健投资的重大结构性变化 无论是在联邦还是在工业上的研究。最后，由于医疗保健资金的戏剧性系统性变化 结构，对高等教育毕业生，特别是博士毕业生的职业生涯的影响是相当大的 很深刻。在不断变化的动态格局中，我们假设根本的瓶颈与 临床翻译研究可以随着熟悉的工程师的培训而大大放松 以人类治疗和培训为基础的新型技术平台的建立。我们进一步假设 人类环境中持续不断的科学发现以及新的治疗方法 高度依赖这些基于技术的平台。该培训计划的目的是创建一种新的 一支能够创造、开发、实施、临床评估和翻译的研究人员队伍 方法、设备、算法和系统被设计成明确地聚焦于一种特定的医学应用， 即，促进手术/介入过程及其结果。在主题上，我们的实习生和培训 该计划将有一个中心重点-治疗和发现的创新平台技术。虽然这件事 培训计划解决生物医学研究中的紧迫问题，即翻译和促进 人类调查系统，该计划还通过以下方式改善高等教育职业发展轨迹 提供一种新颖的职业发展氛围。简而言之，培训计划是2年级、3年级 以新的双疗程临床沉浸序列为中心的计划(第一个疗程是上下文较重的 医生介绍他们的专业和临床现实的经验，以及第二个课程，即 学生嵌入临床团队的密集沉浸式环境)。在这两门课程中，学生们 被要求从事与疾病和治疗分析相关的说明性写作，具有挑衅性 问题解决，临床结果分析和审查，以及模拟拨款申请。该框架支持 给工科教育带来了独特的教育范式。除了这个序列，训练还在继续 加上与手术/介入指导和交付相关的领域中的额外课程工作， 介入成像、医学图像处理和分析、机器人学和医疗器械设计、建模和 模拟、介入治疗学，以及本周期的新知识、介入和外科数据科学。这就是全部 发生在工程、手术和干预的最具战略配置的环境之一 在世界上。这是一个外科和介入领域创新工程研究的培训计划。