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Training Program for Innovative Engineering Research in Surgery and Intervention

外科和介入创新工程研究培训计划

基本信息

批准号：
10837277
负责人：
Michael Ian Miga
金额：
$ 5.38万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-06-01 至 2024-05-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10837277
关键词：
Engineering Intervention Operative Surgical Procedures Research Training Programs innovation

项目摘要

TRAINING PROGRAM SUMMARY Over the past several decades, dramatic breakthroughs in biomedical science have been witnessed within laboratory research. The ability to translate those discoveries as well as to make new discoveries within human investigations has been a challenge and has been often characterized as the bottleneck of clinical research. Added to this context has been the dramatic changes to healthcare organizational environments, constraints on delivery, efficiency, and reimbursements to include major structural changes to the investment in healthcare research, both federally, and industrially. Lastly, as a result of dramatic systemic changes in healthcare funding structure, the impact on higher educational graduates’ careers, specifically doctoral graduates, has been quite profound. Within that changing dynamic landscape, we hypothesize that the fundamental bottlenecks associated with clinical translational research can be dramatically loosened with the training of engineers intimately familiar with human treatment and trained in the inception of novel technology-based platforms. We further hypothesize that continued scientific discoveries within the human environment as well as novel treatment approaches are highly dependent on these technology-based platforms. The purpose of this training program is to create a new cadre of researchers capable of creating, developing, implementing, clinically evaluating, and translating methods, devices, algorithms, and systems designed with a clear focus at one particular application of medicine, namely, to facilitate surgical/interventional processes and their outcomes. Thematically, our trainees and training program will have a central focus – innovative platform technologies for treatment and discovery. While this training program addresses pressing problems in biomedical research, namely the translation and facilitation of human investigative systems, the program also speaks to improving higher education career trajectories by providing a novel professional development atmosphere. Briefly described, the training program is a year 2, 3 program that centers on a novel dual-course clinical immersion sequence (a first course that is a context heavy experience with physicians introducing their specialty and clinical realities, and a second course that is an intensively immersive environment with students embedded within the clinical team). In both courses, students are required to engage in expository writing associated with disease and therapeutic analysis, provocative question solutions, clinical outcome analysis and reviews, and mock grant applications. This framework supports a unique educational paradigm brought to engineering education. Apart from this sequence, training continues with addition course work among areas associated with surgical/interventional guidance and delivery, interventional imaging, medical image processing and analysis, robotics and medical device design, modeling & simulation, interventional therapeutics, and new to this cycle, interventional and surgical data science. This all takes place in one of the most strategically collocated environments for engineering, surgery, and intervention in the world. This is a Training Program for Innovative Engineering Research in Surgery and Intervention.

培训摘要在过去的几十年里，生物医学科学的重大突破已经在实验室研究翻译这些发现并在人类内部做出新发现的能力研究一直是一个挑战，并且常常被描述为临床研究的瓶颈。在此背景下，医疗保健组织环境发生了巨大变化，交付、效率和报销，包括医疗保健投资的重大结构性变化研究，无论是联邦政府，还是工业界。最后，由于医疗保健资金的巨大系统性变化，结构，对高等教育毕业生的职业生涯的影响，特别是博士毕业生，一直相当深刻在不断变化的动态环境中，我们假设，临床转化研究可以大大放松，接受人性化治疗，并接受基于新技术平台的培训。我们进一步假设人类环境中持续的科学发现以及新的治疗方法，高度依赖这些基于技术的平台。该培训计划的目的是创造一个新的能够创建、开发、实施、临床评估和翻译的研究人员骨干方法、设备、算法和系统设计成明确关注一种特定的医学应用，即，促进手术/介入过程及其结果。从主题上讲，我们的学员和培训该计划将有一个中心重点-创新的平台技术的治疗和发现。虽然这培训计划解决了生物医学研究中的紧迫问题，即翻译和促进人类调查系统，该计划还谈到改善高等教育的职业轨迹，提供了一个新的专业发展氛围。简单地说，培训计划是一年2，3 一个程序，集中在一个新的双课程临床沉浸序列（第一个课程，是一个上下文重医生介绍他们的专业和临床现实的经验，第二门课程是一个与临床团队中嵌入的学生的强烈沉浸式环境）。在这两门课程中，学生必须从事与疾病和治疗分析有关的简要写作，问题解决方案，临床结果分析和审查，以及模拟拨款申请。该框架支持为工程教育带来了独特的教育范式。除了这个序列，训练继续进行在与手术/介入指导和交付相关的领域中进行额外的课程工作，介入成像，医学图像处理和分析，机器人和医疗设备设计，建模和模拟、介入治疗学以及新的介入和外科数据科学。这一切在工程、手术和干预最具战略性的环境中进行世界上这是一个手术和干预创新工程研究的培训计划。

项目成果

期刊论文数量（62）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Multidimensional Clutter Filtering of Aperture Domain Data for Improved Blood Flow Sensitivity.

DOI：
10.1109/tuffc.2021.3073292
发表时间：
2021-08
期刊：
IEEE transactions on ultrasonics, ferroelectrics, and frequency control
影响因子：
0
作者：
Ozgun KA;Byram BC
通讯作者：
Byram BC

Impact of deformation on a supine-positioned image-guided breast surgery approach.

DOI：
10.1007/s11548-021-02452-8
发表时间：
2021-11
期刊：
International journal of computer assisted radiology and surgery
影响因子：
3
作者：
通讯作者：

Backward Planning for a Multi-Stage Steerable Needle Lung Robot.

DOI：
10.1109/lra.2021.3066962
发表时间：
2021-04
期刊：
IEEE robotics and automation letters
影响因子：
5.2
作者：
Hoelscher J;Fu M;Fried I;Emerson M;Ertop TE;Rox M;Kuntz A;Akulian JA;Webster RJ 3rd;Alterovitz R
通讯作者：
Alterovitz R

Exceeding traditional curvature limits of concentric tube robots through redundancy resolution.

通过冗余分辨率超越同心管机器人的传统曲率限制。