Administrative Core

项目摘要/摘要 行政核心(核心A)将支持HIVRAD的科学和方案活动 计划并为计划提供必要的基础设施，以实现其总体研究目标 以最有效率和最有效的方式制定和实施里程碑。核心A有以下具体目标：(1)提供 科学领导和协调HIVRAD的活动，确保实现我们的科学目标 同时最大限度地促进科学协作；(2)优化参与科学研究的人员之间的沟通 调查人员之间，以及项目领导人、科学顾问委员会和NIH项目官员之间；以及 (三)提供财政监督、行政支持，确保监管和拨款政策合规。堆芯 A将由首席调查员Leonidas Stamatatos博士领导，他将管理、监督和协调 在项目经理的协助下，计划中每个参与者的努力。一群外部的 将成立科学顾问，以监督HIVRAD的科学活动，并提供建议和 支持。这个核心将监督和整合研究项目和科学核心的执行。堆芯 A监督该计划的方方面面，包括科学问题、法规事务、财务、通信、 协调和管理每个核心和项目。这一核心将确保支出和 预测与整个项目的目标相称；监测财政和职能方面的情况 所有分包合同；并与参与机构的赞助研究办公室协调 赠款资金的支付、支出和核算。该核心将协调准备和 提交科学和财务报告，促进制定管理方案，并确保 监管合规性。将利用各种工具促进通信，包括专用的、 外部SharePoint站点，用作计划数据、法规遵从性的集中存储库 文件、机构间和材料转让协定以及相关出版物、摘要和 演示文稿。

PROJECT SUMMARY / ABSTRACT The Administrative Core (Core A) will support the scientific and programmatic activities of our HIVRAD Program and provide the necessary infrastructure for the Program to achieve its overall research objectives and milestones in the most efficient and effective manner. Core A has the following specific aims: (1) to provide scientific leadership and coordination of the HIVRAD’s activities, assuring achievement of our scientific goals while maximizing scientific collaboration; (2) to optimize communication among the participating scientific investigators; and between Project Leaders, the Scientific Advisory Board, and the NIH Program Officer; and (3) to provide fiscal oversight, administrative support, and ensure regulatory and grant policy compliance. Core A will be led by the Principal Investigator, Dr. Leonidas Stamatatos, who will manage, oversee and coordinate the efforts of each participant in the Program, with the assistance of the Project Manager. A group of external Scientific Advisors will be formed to oversee the scientific activities of the HIVRAD and provide advice and support. This Core will oversee and integrate the execution of the research Projects and Scientific Core. Core A oversees all aspects of this Program including scientific issues, regulatory affairs, finance, communication, coordination and administration of each of the Cores and Projects. This Core will ensure that expenditures and projections are commensurate with the goals of the overall project; monitor the fiscal and functional aspects of all subcontracts; and coordinate with the Offices of Sponsored Research at participating Institutions for the disbursement, expenditure and accounting of grant funds. This Core will coordinate the preparation and submission of scientific and financial reports, facilitate the establishment of regulatory protocols and ensure regulatory compliance. Communications will be facilitated utilizing a variety of tools, including a dedicated, external SharePoint site, which will serve as a centralized repository for Program data, regulatory compliance documents, inter-institutional and material transfer agreements and relevant publications, abstracts and presentations.