Administrative Core (AC)

项目总结--行政核心 行政核心(AC)将提供一个结构，促进有效和综合的互动 TCORS团队。咨询委员会将确保所有方案活动都集中在实现中心的总体目标上 --利用我们的综合主题--《翻转剧本》：利用业界的尼古丁攻略最大化 公共健康，了解工业尼古丁如何在电子烟(ECs)和口服尼古丁中进行操纵 袋子(ONP)正在影响产品的吸引力、成瘾性、使用模式和毒性。生成的数据将 告知关于尼古丁操纵的有效产品标准和营销法规，目的是 劝阻年轻人，包括非使用者，不要使用ECs和ONPs，但仍然提供了一种令人满意的和较少的 完全改用的成年烟草使用者(吸烟者和无烟烟草使用者)的有害替代品 这些产品。咨询委员会将通过以下方式促进和促进每个组成部分(核心和项目)的目标 中心活动的科学指导、行政支持、监督和整合，以确保运营 效率。咨询委员会的具体目标是：1)通过以下方式提供总体研究指导和中心监督 制定研究议程的重点是确定尼古丁的操纵和产品的各个方面 包装、影响产品吸引力、成瘾性和毒性；2)促进内部沟通和整合 该中心以及促进其他受资助的技术合作研究机构、分析协调中心、 科学、增强和物流(CASEL)、烟草快速监测中心(CRST)和 FDA和NIH工作人员；3)协调和组织委员会结构和沟通，并确保运作 提高中心所有项目、试点研究和核心的效率；以及4)促进烟草法规的传播 研究成果，包括数据共享。对于最后一个目标，翻译烟草政策团队(TPT)将 进行监督并提供关键输入，确保研究数据具有翻译影响，从而为有效的信息提供信息 烟草政策。AC将确保中心的所有组件无缝协作，以完成 该中心的总体目标和组件特定目标。来自我们中心项目的结果数据将通知 有效的尼古丁产品标准和营销法规，劝阻年轻的非吸烟者 不再使用ECs和ONPs，但仍然为成年烟草使用者提供了一种令人满意且危害较小的替代方案。

PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core (AC) will provide a structure to facilitate effective and integrative interactions between the TCORS team. The AC will ensure all programmatic activities focus on achieving the overall goal of the Center – using our integrative theme, “Flipping the Script”: Using the Industry's Nicotine Playbook to Maximize Public Health, to understand how industry nicotine manipulations in electronic cigarettes (ECs) and oral nicotine pouches (ONPs) are impacting product appeal, addictiveness, use patterns, and toxicity. The resulting data will inform effective product standards and marketing regulations on nicotine manipulations with the intent to dissuade young people, including non-users, from using ECs and ONPs, but still provide a satisfying and less harmful alternative for adult tobacco users (smokers and smokeless tobacco users) who completely switch to these products. The AC will foster and promote the goals of each component (cores and projects) by providing scientific direction, administrative support, oversight, and integration of Center activities to ensure operational efficiency. The Specific Aims of the AC are to: 1) Provide overall research direction and center oversight by setting the research agenda focused on determining how manipulation of nicotine and aspects of product packaging, impact product appeal, addictiveness, and toxicity; 2) Promote communication and integration within the Center as well as promote interaction between other funded TCORS, the Center for Coordination of Analysis, Science, Enhancement, and Logistics (CASEL), the Center for Rapid Surveillance of Tobacco (CRST), and the FDA and NIH staff; 3) Coordinate and organize committee structure and communications, and ensure operational efficiency for all projects, pilot studies and cores of the center; and 4) Foster dissemination of tobacco regulatory research findings, including data sharing. For this last aim, the Translational Tobacco Policy Team (TPT) will have oversight and provide critical input ensuring research data has translational impact to inform effective tobacco policy. The AC will ensure that all components of the Center work seamlessly together to accomplish the overall and component-specific goals of this Center. The resulting data from our center projects will inform effective product standards and marketing regulations on nicotine dimensions that dissuade young non-users from using ECs and ONPs but still provide a satisfying and less harmful alternative for adult tobacco users.