Superconducting scanner magnet for much lower cost, compact proton therapy systems

超导扫描仪磁体可实现成本更低的紧凑型质子治疗系统

• 批准号: 10546708
• 负责人: Alexander Otto
• 金额: $ 35.95万
• 依托单位: SOLID MATERIAL SOLUTIONS, LLC
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2023-09-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10546708
• 关键词: Capital; Collaborations; Consumption; Copper; Cyclotrons; Development; Dimensions; Environmental Wind; Europe; Evaluation; Filament; Foundations; Funding; Goals; Height; High temperature of physical object; Length; Liquid substance; Malignant Neoplasms; Manufacturer Name; Marketing; Mechanics; Medical; Motor; Participant; Pathway interactions; Patients; Performance; Phase; Plug-in; Positioning Attribute; Price; Production; Property; Psychological reinforcement; Radial; Ramp; Reaction; Roentgen Rays; Shapes; Small Business Innovation Research Grant; Solid; System; Techniques; Technology; Temperature; Testing; Textiles; Time; Tissues; Treatment Cost; United States National Aeronautics and Space Administration; United States National Institutes of Health; Validation; X-Ray Medical Imaging; X-Ray Therapy; base; cold temperature; cost; density; design; experience; next generation; programs; proton beam; proton therapy; sensor; therapy design; therapy development; tumor; voltage; wound

Solid Material Solutions, LLC (SMS) SBIR Phase 1 ABSTRACT NIH FOA PA-21-259 Proposal Title: Superconducting scanner magnet for much lower cost compact proton therapy systems Proton Therapy (PT) is a proven, superior technique for treating cancer tumors compared to conventional X- ray therapy that can cause excessive healthy tissue damage. Yet it is available to less than 4% of the patients that would benefit from it, because for widespread usage, compact, much lower cost PT systems are required with much smaller magnets using High Temperature Superconductors (HTS) that generate higher fields at affordable operating conditions than current copper and Low Temperature Superconductor (LTS) magnets. Although PT system manufacturers have been developing more compact, lower cost PT systems, none have yet attained the combination of adequately low cost and reduced size to fit into much smaller treatment rooms, and full capabilities of the larger and costlier systems. It is specifically a key requirement for the PT system to fit into the small, low-cost treatment rooms that are already well established for low-cost X-Ray treatment. An essential component for the development of this ultra-compact, low-cost PT system is a much shorter HTS scanner magnet. This program will now develop a sufficiently short scanner magnet that recently became attainable due to breakthrough advances with the HTS-2212 material at Solid Material Solutions on wires, cables and coils for fast-ramp usage where inductive losses require advanced, low-loss conductor of the type required for this application. The specific product objective is a 4-coil scanner magnet that is one third the length of present magnets. It will include conduction cooling pathways, a cryo-envelope, current leads and control sensors. It will be readily plugged into the ultra-low-cost PT system and deliver the same performance as present magnets while also consuming 1/10th the electrical power. The Phase 1 program is aimed at establishing a specific 2212-based cable design and validating its production, along with design and fabrication of a low-loss demonstration coil with required radial build, current (Ic), and current density (Je) at the affordable cooling temperature regime of > 20K. This will be achieved by 1) Establishing specific wire and cable designs along with validation of their fabricability and properties 2) Developing specific capability to wind these cables into racetrack coil modules of the target radial build, overall shorter dimensions and with the required current and current densities to attain 2T at temperatures of 20 K or greater, and 3) Developing capability to fabricate coils of the target axial length from the racetrack modules, along with mechanical fixtures, current leads and voltage taps, followed by validation of its capability to generate the target 2 T at > 20 K in the dipole coil gap where the proton beam would be deflected. These developments will provide basis and justification for completing in a subsequent Phase II program, the commercial design, development and qualification of a full scale, conduction cooled coil set and magnet system that meets all requirements. When fully developed, this plug-in shorter scanner magnet will enable compact PT systems to be retro-fit height-wise into widely used treatment rooms of the kinds used for X-Ray therapy.

Solid Material Solutions, LLC (SMS) SBIR 第 1 阶段 摘要 NIH FOA PA-21-259 提案标题：用于成本更低的紧凑型质子治疗系统的超导扫描仪磁体 与传统的 X 射线治疗相比，质子治疗 (PT) 是一种经过验证的、优越的癌症肿瘤治疗技术。 射线治疗可能会导致过度的健康组织损伤。然而只有不到 4% 的患者可以使用该药物 会从中受益，因为为了广泛使用，需要紧凑、成本低得多的 PT 系统 使用高温超导体 (HTS) 的较小磁体，以经济实惠的运行方式产生更高的磁场 比目前的铜和低温超导 (LTS) 磁体的条件更好。虽然PT系统 制造商一直在开发更紧凑、成本更低的 PT 系统，但尚未实现将 足够低的成本和减小的尺寸，以适应更小的治疗室，以及更大和更大的治疗室的全部功能 更昂贵的系统。 PT 系统适合小型、低成本治疗室的一个关键要求是 已经为低成本 X 射线治疗建立了良好的基础。 开发这种超紧凑、低成本 PT 系统的一个重要组成部分是更短的 HTS 扫描仪磁铁。该计划现在将开发一种足够短的扫描仪磁铁，最近已成为可能 由于固体材料解决方案公司的 HTS-2212 材料在电线、电缆和线圈方面取得了突破性进展， 快速斜坡使用，其中电感损耗需要该应用所需类型的先进、低损耗导体。 具体产品目标是 4 线圈扫描仪磁铁，其长度是现有磁铁的三分之一。它将 包括传导冷却路径、低温封套、电流引线和控制传感器。它将很容易被插入 集成到超低成本 PT 系统中，提供与现有磁铁相同的性能，同时功耗仅为现有磁铁的 1/10 电力。 第一阶段计划旨在建立基于 2212 的特定电缆设计并验证其生产， 以及具有所需径向构造、电流 (Ic) 和电流的低损耗演示线圈的设计和制造 在可承受的冷却温度范围 > 20K 下的密度 (Je)。这将通过以下方式实现： 1) 建立具体的 电线和电缆设计以及对其可制造性和性能的验证 2) 开发特定能力 将这些电缆缠绕成目标径向结构的跑道线圈模块，整体尺寸较短，并且 在 20 K 或更高温度下达到 2T 所需的电流和电流密度，以及 3) 开发能力 从跑道模块制造目标轴向长度的线圈，以及机械固定装置、电流引线和 电压抽头，然后验证其在偶极线圈间隙中生成 > 20 K 目标 2 T 的能力，其中 质子束将会偏转。 这些进展将为完成后续第二阶段计划提供基础和理由， 全尺寸传导冷却线圈组和磁体系统的商业设计、开发和鉴定 满足所有要求。开发完成后，这种插入式较短扫描仪磁铁将使紧凑型 PT 系统能够 可以对高度进行改造，以适应广泛使用的用于 X 射线治疗的治疗室。