Superconducting scanner magnet for much lower cost, compact proton therapy systems

超导扫描仪磁体可实现成本更低的紧凑型质子治疗系统

• 批准号: 10546708
• 负责人: Alexander Otto
• 金额: $ 35.95万
• 依托单位: SOLID MATERIAL SOLUTIONS, LLC
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2023-09-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10546708
• 关键词: Capital; Collaborations; Consumption; Copper; Cyclotrons; Development; Dimensions; Environmental Wind; Europe; Evaluation; Filament; Foundations; Funding; Goals; Height; High temperature of physical object; Length; Liquid substance; Malignant Neoplasms; Manufacturer Name; Marketing; Mechanics; Medical; Motor; Participant; Pathway interactions; Patients; Performance; Phase; Plug-in; Positioning Attribute; Price; Production; Property; Psychological reinforcement; Radial; Ramp; Reaction; Roentgen Rays; Shapes; Small Business Innovation Research Grant; Solid; System; Techniques; Technology; Temperature; Testing; Textiles; Time; Tissues; Treatment Cost; United States National Aeronautics and Space Administration; United States National Institutes of Health; Validation; X-Ray Medical Imaging; X-Ray Therapy; base; cold temperature; cost; density; design; experience; next generation; programs; proton beam; proton therapy; sensor; therapy design; therapy development; tumor; voltage; wound

Solid Material Solutions, LLC (SMS) SBIR Phase 1 ABSTRACT NIH FOA PA-21-259 Proposal Title: Superconducting scanner magnet for much lower cost compact proton therapy systems Proton Therapy (PT) is a proven, superior technique for treating cancer tumors compared to conventional X- ray therapy that can cause excessive healthy tissue damage. Yet it is available to less than 4% of the patients that would benefit from it, because for widespread usage, compact, much lower cost PT systems are required with much smaller magnets using High Temperature Superconductors (HTS) that generate higher fields at affordable operating conditions than current copper and Low Temperature Superconductor (LTS) magnets. Although PT system manufacturers have been developing more compact, lower cost PT systems, none have yet attained the combination of adequately low cost and reduced size to fit into much smaller treatment rooms, and full capabilities of the larger and costlier systems. It is specifically a key requirement for the PT system to fit into the small, low-cost treatment rooms that are already well established for low-cost X-Ray treatment. An essential component for the development of this ultra-compact, low-cost PT system is a much shorter HTS scanner magnet. This program will now develop a sufficiently short scanner magnet that recently became attainable due to breakthrough advances with the HTS-2212 material at Solid Material Solutions on wires, cables and coils for fast-ramp usage where inductive losses require advanced, low-loss conductor of the type required for this application. The specific product objective is a 4-coil scanner magnet that is one third the length of present magnets. It will include conduction cooling pathways, a cryo-envelope, current leads and control sensors. It will be readily plugged into the ultra-low-cost PT system and deliver the same performance as present magnets while also consuming 1/10th the electrical power. The Phase 1 program is aimed at establishing a specific 2212-based cable design and validating its production, along with design and fabrication of a low-loss demonstration coil with required radial build, current (Ic), and current density (Je) at the affordable cooling temperature regime of > 20K. This will be achieved by 1) Establishing specific wire and cable designs along with validation of their fabricability and properties 2) Developing specific capability to wind these cables into racetrack coil modules of the target radial build, overall shorter dimensions and with the required current and current densities to attain 2T at temperatures of 20 K or greater, and 3) Developing capability to fabricate coils of the target axial length from the racetrack modules, along with mechanical fixtures, current leads and voltage taps, followed by validation of its capability to generate the target 2 T at > 20 K in the dipole coil gap where the proton beam would be deflected. These developments will provide basis and justification for completing in a subsequent Phase II program, the commercial design, development and qualification of a full scale, conduction cooled coil set and magnet system that meets all requirements. When fully developed, this plug-in shorter scanner magnet will enable compact PT systems to be retro-fit height-wise into widely used treatment rooms of the kinds used for X-Ray therapy.

固体材料解决方案有限责任公司(SMS)SBIR阶段1摘要NIH FOA PA-21-259 提案标题：用于低成本紧凑型质子治疗系统的超导扫描仪磁体 质子治疗(PT)是一种经过验证的治疗癌症的优越技术，与传统的X-射线治疗相比， 射线疗法可能会导致过度的健康组织损伤。然而，只有不到4%的患者可以使用它 将从中受益，因为对于广泛使用，紧凑、成本低得多的PT系统需要 使用高温超导体(HTS)的较小磁体，可在负担得起的运行中产生更高的磁场 比目前的铜和低温超导(LTS)磁体条件更好。虽然PT系统 制造商一直在开发更紧凑、更低成本的PT系统，目前还没有一家达到 足够低的成本和更小的尺寸，可以容纳更小的治疗室，以及更大和更小的 成本更高的系统。PT系统特别适用于小的、低成本的治疗室 已经为低成本的X射线治疗建立了良好的基础。 开发这种超紧凑、低成本的PT系统的一个重要组件是短得多的HTS 扫描仪磁铁。该计划现在将开发一种足够短的扫描仪磁铁，这种磁铁最近已经可以实现 由于HTS-2212材料在固体材料解决方案领域取得的突破性进展，适用于 在电感损耗需要此应用所需类型的先进、低损耗导体的情况下，快速斜坡使用。 具体的产品目标是一种4线圈扫描仪磁铁，其长度是目前磁铁的三分之一。会的 包括传导冷却通道、低温封套、电流引线和控制传感器。它会很容易地插上 进入超低成本的PT系统，提供与目前磁铁相同的性能，同时也消耗十分之一的成本 电力。 第一阶段计划旨在建立特定的基于2212的电缆设计并验证其生产， 以及设计和制造具有所需径向构建、电流(IC)和电流的低损耗演示线圈 在&gt；20K的可承受冷却温度条件下的密度(Je)。这将通过以下方式实现：1)建立具体的 电线和电缆设计以及对其可制造性和性能的验证2)开发特定能力以 将这些电缆缠绕到目标径向构建的赛道线圈模块中，总体尺寸较短，并具有 在20K或更高的温度下达到2T所需的电流和电流密度，以及3)开发能力以 从赛道模块制造目标轴向长度的线圈，以及机械夹具、电流引线和 电压抽头，然后验证其在偶极线圈间隙中产生2 T at&gt；20K目标的能力，其中 质子束将会偏转。 这些进展将为完成后续的第二阶段计划提供基础和理由 商业设计、开发和鉴定全尺寸传导冷却线圈组和磁体系统， 符合所有要求。完全开发后，这种插入式较短的扫描仪磁铁将使紧凑型PT系统能够 将高度调整到广泛使用的X光治疗所用的治疗室。