Superconducting scanner magnet for much lower cost, compact proton therapy systems

超导扫描仪磁体可实现成本更低的紧凑型质子治疗系统

• 批准号: 10546708
• 负责人: Alexander Otto
• 金额: $ 35.95万
• 依托单位: SOLID MATERIAL SOLUTIONS, LLC
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2023-09-21
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10546708
• 关键词: Capital; Collaborations; Consumption; Copper; Cyclotrons; Development; Dimensions; Environmental Wind; Europe; Evaluation; Filament; Foundations; Funding; Goals; Height; High temperature of physical object; Length; Liquid substance; Malignant Neoplasms; Manufacturer Name; Marketing; Mechanics; Medical; Motor; Participant; Pathway interactions; Patients; Performance; Phase; Plug-in; Positioning Attribute; Price; Production; Property; Psychological reinforcement; Radial; Ramp; Reaction; Roentgen Rays; Shapes; Small Business Innovation Research Grant; Solid; System; Techniques; Technology; Temperature; Testing; Textiles; Time; Tissues; Treatment Cost; United States National Aeronautics and Space Administration; United States National Institutes of Health; Validation; X-Ray Medical Imaging; X-Ray Therapy; base; cold temperature; cost; density; design; experience; next generation; programs; proton beam; proton therapy; sensor; therapy design; therapy development; tumor; voltage; wound

Solid Material Solutions, LLC (SMS) SBIR Phase 1 ABSTRACT NIH FOA PA-21-259 Proposal Title: Superconducting scanner magnet for much lower cost compact proton therapy systems Proton Therapy (PT) is a proven, superior technique for treating cancer tumors compared to conventional X- ray therapy that can cause excessive healthy tissue damage. Yet it is available to less than 4% of the patients that would benefit from it, because for widespread usage, compact, much lower cost PT systems are required with much smaller magnets using High Temperature Superconductors (HTS) that generate higher fields at affordable operating conditions than current copper and Low Temperature Superconductor (LTS) magnets. Although PT system manufacturers have been developing more compact, lower cost PT systems, none have yet attained the combination of adequately low cost and reduced size to fit into much smaller treatment rooms, and full capabilities of the larger and costlier systems. It is specifically a key requirement for the PT system to fit into the small, low-cost treatment rooms that are already well established for low-cost X-Ray treatment. An essential component for the development of this ultra-compact, low-cost PT system is a much shorter HTS scanner magnet. This program will now develop a sufficiently short scanner magnet that recently became attainable due to breakthrough advances with the HTS-2212 material at Solid Material Solutions on wires, cables and coils for fast-ramp usage where inductive losses require advanced, low-loss conductor of the type required for this application. The specific product objective is a 4-coil scanner magnet that is one third the length of present magnets. It will include conduction cooling pathways, a cryo-envelope, current leads and control sensors. It will be readily plugged into the ultra-low-cost PT system and deliver the same performance as present magnets while also consuming 1/10th the electrical power. The Phase 1 program is aimed at establishing a specific 2212-based cable design and validating its production, along with design and fabrication of a low-loss demonstration coil with required radial build, current (Ic), and current density (Je) at the affordable cooling temperature regime of > 20K. This will be achieved by 1) Establishing specific wire and cable designs along with validation of their fabricability and properties 2) Developing specific capability to wind these cables into racetrack coil modules of the target radial build, overall shorter dimensions and with the required current and current densities to attain 2T at temperatures of 20 K or greater, and 3) Developing capability to fabricate coils of the target axial length from the racetrack modules, along with mechanical fixtures, current leads and voltage taps, followed by validation of its capability to generate the target 2 T at > 20 K in the dipole coil gap where the proton beam would be deflected. These developments will provide basis and justification for completing in a subsequent Phase II program, the commercial design, development and qualification of a full scale, conduction cooled coil set and magnet system that meets all requirements. When fully developed, this plug-in shorter scanner magnet will enable compact PT systems to be retro-fit height-wise into widely used treatment rooms of the kinds used for X-Ray therapy.

Solid Material Solutions，LLC（SMS）SBIR第1阶段摘要NIH FOA PA-21-259 提案标题：用于低成本紧凑型质子治疗系统的超导扫描仪磁体 质子治疗（PT）是一种经过验证的，与传统的X-射线治疗相比，上级的癌症治疗技术。 射线治疗，可导致过度的健康组织损伤。然而，只有不到4%的患者可以使用， 将从中受益，因为对于广泛的使用，需要紧凑，成本低得多的PT系统， 使用高温超导体（HTS）的小型磁体，可在经济实惠的运行条件下产生更高的磁场 比目前的铜和低温超导体（LTS）磁体的条件。虽然PT系统 制造商一直在开发更紧凑、成本更低的PT系统，但还没有一家实现 足够低的成本和减小的尺寸，以适应更小的治疗室，以及更大和更小的治疗室的全部功能。 更昂贵的系统。对于PT系统来说，一个关键的要求是要适合小型、低成本的治疗室 已经为低成本的X射线治疗建立了良好的基础。 开发这种超紧凑、低成本PT系统的一个重要组成部分是更短的HTS 扫描仪磁铁该计划现在将开发一个足够短的扫描仪磁铁， 由于固体材料解决方案在电线、电缆和线圈上使用HTS-2212材料的突破性进展， 快速斜坡应用，其中电感损耗需要该应用所需类型的高级低损耗导体。 具体的产品目标是一个4线圈扫描仪磁铁，是目前磁铁长度的三分之一。它将 包括传导冷却路径、低温外壳、电流引线和控制传感器。它会很容易被堵住 在超低成本的PT系统中，提供与现有磁体相同的性能，同时消耗1/10 电力。 第一阶段计划旨在建立一个特定的基于2212的电缆设计和验证其生产， 沿着具有所需径向构造、电流（Ic）和电流的低损耗演示线圈的设计和制造 密度（Je）在> 20 K的可承受的冷却温度制度下。这将通过以下方式实现：（1）建立具体的 电线和电缆设计沿着，并对其可制造性和性能进行验证2）开发特定能力， 将这些电缆缠绕到目标径向构造的跑道线圈模块中，整体尺寸较短， 在20 K或更高的温度下达到2 T所需的电流和电流密度，以及3）开发能力， 利用轨道模块，沿着机械夹具、电流引线和 电压抽头，然后验证其在偶极线圈间隙中在> 20 K时产生目标2 T的能力，其中 质子束会发生偏转 这些发展将为在随后的第二阶段计划中完成 全尺寸传导冷却线圈组和磁体系统的商业设计、开发和鉴定， 符合所有要求。当完全开发后，这种插入式较短的扫描仪磁铁将使紧凑的PT系统， 在高度上被改装到广泛使用的用于X射线治疗的治疗室中。