Rapid Production of Metal Organic Framework - Fabrics for Air Filtration

快速生产金属有机骨架 - 空气过滤织物

• 批准号: 10546842
• 负责人: Nick Cienski
• 金额: $ 25.95万
• 依托单位: HAVA, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10546842
• 关键词: Rapid; Production; Metal; Organic; Framework

A year and a half later after the pandemic, it is evident that wearing masks for personal and public health concerns is an ongoing matter, with events like the arrival and spread of the Delta and Omicron variants of SARS CoV-2. Although it is well known that the N95 masks are the “golden standard” for protection, the public still overwhelmingly prefers cloth-based masks, due to the uncomfortable feeling and lack of reusability of the N95 mask, and the ease of breathing of the cloth-based masks. ASTM International recently published the ASTM F3502-21 standard, which creates guidelines for the efficacy of “Barrier Face Coverings” that are neither medical masks nor respirators and are primarily directed towards cloth masks. However, there are very few masks that are fabric-based (without extra insert filters) that pass this standard, and none that are washable and reusable. The goal of our company, Hava Technologies, is to create a cloth mask that has the benefits of a traditional cloth mask, such as breathability and washability, while still passing the ASTM-F3502 standard for filtration efficacy. To do this, we utilize a novel technology called metal-organic frameworks (MOFs). The electrostatic-based filtration of MOFs has shown filtration efficacy approaching and matching the ASTM F3502 Level 1 standard. More interestingly, these MOF-fabrics show effective filtration after 25 wash cycles, showing the capability of these MOF-fabric based masks and filters to be truly washable and reusable for months. The proposal will focus on the following specific aims: 1. Creation of MOF-fabric with uniform ASTM F3502 Level 1 standard and ensuring safety during usage. 2. Washable MOF-fabrics simulating home use conditions, including hot water and detergents. 3. Large area production of MOF-fabrics using standard roll-to-roll coating processing, including a public health survey of attitudes towards mask wearing. Wearers of Hava MOF-coated fabric masks will benefit by breathing air with significantly higher filtration efficiency than uncoated cloth masks. It is reasonable to expect protective masks with increased efficiency in sub-micron filtering capability would reduce transmission of SARS CoV-2 and subsequently reduce COVID-19 incidence with its associated morbidity, mortality, and adverse economic impact. According to a recent market research report, the global mask market is expected to surpass $1.2B in 2020 (Research Drive 2020), showing a viable commercialization strategy for the company.

大流行一年半后，很明显，个人和家庭佩戴口罩 随着三角洲的到来和扩散，公共卫生问题是一个持续的问题 和SARS CoV-2的Omicron变体。虽然众所周知，N95口罩是 作为防护的“黄金标准”，公众仍然压倒性地喜欢布基口罩， N95面罩的不舒适感和缺乏可重复使用性，以及呼吸的舒适性 布制面具ASTM国际最近发布了ASTM F3502-21标准， 它为“屏障式面部覆盖物”的功效制定了指导方针， 面罩也不是呼吸器，并且主要针对布面罩。然而， 一些基于织物的口罩（没有额外的插入过滤器）通过了该标准， 可以清洗和重复使用。 我们公司的目标，哈瓦技术，是创造一个布面具， 传统布口罩的优点，如透气性和耐洗性，同时仍然通过 ASTM-F3502过滤效率标准。为此，我们利用一种名为 金属有机框架（MOFs）。MOFs的基于静电的过滤已经表明， 过滤效率接近并符合ASTM F3502 1级标准。更 有趣的是，这些MOF织物在25次洗涤循环后显示出有效的过滤，显示出 这些基于MOF织物的口罩和过滤器真正可洗涤和可重复使用的能力， 个月该提案将侧重于以下具体目标： 1.创建符合ASTM F3502 1级标准的MOF织物并确保安全性 在使用过程中。 2.可水洗的MOF织物模拟家庭使用条件，包括热水和洗涤剂。 3.使用标准卷对卷涂布工艺大面积生产MOF织物， 包括一项关于人们对戴口罩态度的公共卫生调查。 Hava MOF涂层织物口罩的佩戴者将受益于呼吸空气， 过滤效率高于无涂层的布口罩。有理由期待保护性的 具有提高的亚微米过滤能力的效率的掩模将减少 SARS CoV-2并随后降低COVID-19发病率及其相关发病率， 死亡率和不利的经济影响。根据最近的一份市场研究报告， 全球口罩市场预计将在2020年超过12亿美元（Research Drive 2020），显示 为公司制定可行的商业化战略。