ESSENCE (Enabling translation of Science to Service to ENhance Depression CarE)
ESSENCE(将科学转化为服务以增强抑郁症 CarE)
基本信息
- 批准号:10630486
- 负责人:
- 金额:$ 19.48万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2023
- 资助国家:美国
- 起止时间:2023-07-01 至 2024-05-31
- 项目状态:已结题
- 来源:
- 关键词:Administrative SupplementAdoptionCaringCommunitiesCommunity Health AidesData AnalysesDepression screenEffectivenessEnrollmentEnsureEvidence based interventionGoalsHealth Services AccessibilityHealth care facilityIndiaInterventionKnowledgeMental DepressionOutpatientsPathway interactionsPatient RecruitmentsPrimary CarePrimary Health CareRandomizedRandomized, Controlled TrialsResearchRuralServicesSeveritiesSymptomsTestingTrainingTranslational ResearchWorld Health Organizationcostdigital technologyevidence basefollow-upimplementation trialimprovedprimary care settingprogramspsychologicremote deliveryscale upscreeninguptake
项目摘要
PROJECT ABSTRACT (OVERALL COMPONENT)
The overall goal of the ESSENCE (Enabling translation of Science to Service to ENhance Depression CarE)
project is to generate knowledge on effective implementation approaches for scaling up of evidence based
interventions for depression in primary care settings in rural India. The ESSENCE Implementation Trial
represents the second of two major trials in the ESSENCE program, and will yield valuable research findings on
the effectiveness and costs of remote strategies that can support the uptake and implementation of a depression
care package based on the World Health Organization's mhGAP program in routine primary care settings in
Sehore district in Madhya Pradesh, India. The ESSENCE Implementation Trial builds directly on the successful
roll out and completion of the ESSENCE Training Trial, which demonstrated the effectiveness of leveraging
digital technology for building workforce capacity by training community health workers to deliver an evidence-
based brief psychological treatment for depression. The ESSENCE Implementation Trial represents the next
critical step in supporting the implementation of depression care, by supporting the primary health care facility
teams with the adoption and integration of depression care, and establishing the referral pathways for screening
and identifying depression cases in the community and then ensuring access to treatment delivered by the newly
trained community health workers. The ESSENCE Implementation Trial consists of a cluster-randomized
controlled trial, enrolling 14 primary care facilities in Sehore district, with 7 facilities randomly assigned to receive
the Enhanced Implementation Support strategy intervention condition, and the remaining 7 facilities randomly
assigned to receive the Routine Implementation Support control condition. Our primary hypothesis is that the
Enhanced Implementation Support, involving remotely delivered coaching and emphasis on quality
improvement, will be superior to Routine Implementation Support in increasing the proportion of outpatients
screened for depression (using the PHQ-9, a common screener for depression). Furthermore, we hypothesize
that among outpatients screened positive with depression, those in facilities randomized to the Enhanced
Implementation Support will show greater reduction in symptom severity at 3-month follow up compared to
outpatients in the Routine Implementation Support control condition. All 14 facilities have been trained in the
mhGAP depression care package, and the implementation support strategies have been tested in April and May,
2022. The official launch of patient recruitment for the Implementation Trial will begin on June 1st, 2022. This
Administrative Supplement will ensure that the key activities for the ESSENCE Implementation Trial can be
completed, and that the data analyses and interpretation of the findings can inform the scale up of depression
care towards reducing the treatment gap for depression care in India and globally.
项目摘要(总体组件)
ESSENCE的总体目标(使科学转化为服务,以增强抑郁症的治疗)
该项目的目的是产生关于有效实施方法的知识,以扩大循证
在印度农村地区的初级保健环境中进行抑郁症干预。ESSENCE实施试验
代表了ESSENCE计划中两项主要试验中的第二项,并将在以下方面产生有价值的研究结果:
可以支持抑郁症的吸收和实施的远程策略的有效性和成本
基于世界卫生组织mhGAP计划的常规初级保健护理包,
印度中央邦的Sehore区。ESSENCE实施试用版直接建立在成功的
推出并完成ESSENCE培训试验,该试验证明了利用
数字技术通过培训社区卫生工作者来建设工作人员的能力,
基于抑郁症的简短心理治疗。ESSENCE实施试验代表了下一个
通过支持初级卫生保健设施,支持实施抑郁症护理的关键步骤
采用和整合抑郁症护理的团队,并建立筛查的转诊途径
并在社区中识别抑郁症病例,然后确保获得由新的
培训社区卫生工作者。ESSENCE实施试验包括一项随机分组试验,
对照试验,在Sehore区招募14家初级保健机构,其中7家机构随机分配接受
强化执行支持战略干预条件,其余7个设施随机
分配接收例行实施支持控制条件。我们的主要假设是
加强执行支助,包括远程辅导和强调质量
改善,将优于常规实施支持在增加门诊病人的比例
筛查抑郁症(使用PHQ-9,一种常见的抑郁症筛查工具)。此外,我们假设
在抑郁症筛查阳性的门诊患者中,
实施支持将在3个月随访时显示症状严重程度的降低幅度大于
门诊病人在常规实施支持控制条件下。所有14个设施都接受了
mhGAP抑郁症护理包,并在4月和5月测试了实施支持策略,
2022.实施试验的患者招募将于2022年6月1日开始正式启动。这
行政补充将确保ESSENCE实施试验的关键活动可以
完成,数据分析和解释的结果可以告知抑郁症的规模扩大
减少印度和全球抑郁症治疗的差距。
项目成果
期刊论文数量(33)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The emergence of digital mental health in low-income and middle-income countries: A review of recent advances and implications for the treatment and prevention of mental disorders.
- DOI:10.1016/j.jpsychires.2020.12.016
- 发表时间:2021-01
- 期刊:
- 影响因子:4.8
- 作者:Carter H;Araya R;Anjur K;Deng D;Naslund JA
- 通讯作者:Naslund JA
Psychological Impact of COVID-19 Pandemic on Frontline Health Workers in Low- and Middle-Income Countries.
- DOI:pii: http://harvardpublichealthreview.org/wp-content/uploads/2020/10/deng-and-naslund-2020-28.pdf
- 发表时间:2020
- 期刊:
- 影响因子:0
- 作者:Deng D;Naslund JA
- 通讯作者:Naslund JA
Development of a Digital Program for Training Community Health Workers in the Detection and Referral of Schizophrenia in Rural India.
开发一项数字计划,以培训社区卫生工作者在印度农村地区进行精神分裂症的检测和转诊。
- DOI:10.1007/s11126-023-10019-w
- 发表时间:2023-06
- 期刊:
- 影响因子:3.5
- 作者:Tyagi, Vidhi;Khan, Azaz;Siddiqui, Saher;Kakra Abhilashi, Minal;Dhurve, Pooja;Tugnawat, Deepak;Bhan, Anant;Naslund, John A
- 通讯作者:Naslund, John A
Schizophrenia Assessment, Referral and Awareness Training for Health Auxiliaries (SARATHA): Protocol for a Mixed-Methods Pilot Study in Rural India.
- DOI:10.3390/ijerph192214936
- 发表时间:2022-11-13
- 期刊:
- 影响因子:0
- 作者:Naslund, John A.;Tyagi, Vidhi;Khan, Azaz;Siddiqui, Saher;Abhilashi, Minal Kakra;Dhurve, Pooja;Mehta, Urvakhsh Meherwan;Rozatkar, Abhijit;Bhatia, Urvita;Vartak, Anil;Torous, John;Tugnawat, Deepak;Bhan, Anant
- 通讯作者:Bhan, Anant
Applying Human-Centered Design in Global Mental Health to Improve Reach Among Underserved Populations in the United States and India.
- DOI:10.9745/ghsp-d-22-00312
- 发表时间:2023-02-28
- 期刊:
- 影响因子:0
- 作者:Black CJ;Berent JM;Joshi U;Khan A;Chamlagai L;Shrivastava R;Gautam B;Negeye A;Iftin AN;Ali H;Desrosiers A;Bhan A;Bhattacharya S;Naslund JA;Betancourt TS
- 通讯作者:Betancourt TS
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