Optimizing Cardiovascular Preventive Care for Women following Hypertensive Disorders of Pregnancy.
优化妊娠期高血压疾病女性的心血管预防护理。
基本信息
- 批准号:10631132
- 负责人:
- 金额:$ 17.71万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2022
- 资助国家:美国
- 起止时间:2022-06-01 至 2027-05-31
- 项目状态:未结题
- 来源:
- 关键词:AddressAdvisory CommitteesAffectAgeAmerican Heart AssociationAreaAttitudeCardiovascular DiseasesCardiovascular systemCaringCause of DeathCessation of lifeClient satisfactionClinicalClinical TrialsCommunicationComplementConduct Clinical TrialsDataDecision AidDecision MakingDevelopmentDiscipline of obstetricsEventEvidence based interventionFutureGoalsHealthHeart DiseasesHypertensionIncidenceInterventionInterviewK-Series Research Career ProgramsKnowledgeLeadershipLearningLifeLongevityMaternal HealthMaternal-fetal medicineMentorsOutcomePatient EducationPatient riskPatient-Focused OutcomesPatientsPerinatalPersonsPhysiciansPilot ProjectsPopulations at RiskPositioning AttributePostpartum PeriodPostpartum WomenPregnancyPregnancy ComplicationsPreventionPreventivePreventive careProcessProviderRecommendationResearchResearch MethodologyResearch PersonnelRiskSelf CareSelf EfficacySilverSpecialistStrokeStructureSymptomsTestingTrainingUnited StatesWomanWomen&aposs HealthWorkburden of illnesscardiovascular disorder preventioncardiovascular disorder riskcardiovascular healthcardiovascular risk factorcareercareer developmentclinical carecommunication aiddesigndisabilityefficacy testingevidence basehealthy pregnancyhigh riskimprovedinnovationlifetime riskmembermenobstetric carepatient engagementpatient orientedpilot trialpregnancy disorderpreventprimary care providerprogramsprototypereproductiveskillsstandard caretherapy designtooltrial comparingtrial design
项目摘要
PROJECT SUMMARY/ABSTRACT
This is a K23 proposal for Dr. Lauren Theilen, a Maternal-Fetal Medicine physician with expertise in long-term
maternal health following hypertensive disorders of pregnancy. In order to investigate strategies for improved
cardiovascular (CV) health among women following complicated pregnancy, this K23 will allow Dr. Theilen to
acquire critical skills in four career development areas: 1) qualitative and mixed methods research approaches;
2) development and refinement of a patient decision aid; 3) design and conduct of clinical trials; and 4)
research leadership and management skills. To achieve her goals, Dr. Theilen has assembled an
interdisciplinary mentoring team comprised of Dr. Michael Varner (Primary Mentor), a senior investigator and
recognized leader in perinatal clinical trials, and three Co-Mentors: Dr. Bob Silver, an accomplished researcher
in the field of pregnancy as a window to future health, Dr. Susan Zickmund, an expert in qualitative and mixed
methods research, and Dr. Elissa Ozanne, a leading investigator in patient risk communication and decision
aid development. Complementing this mentoring team, Dr. Theilen also has a 3-member advisory committee to
support her proposed decision aid development and pilot trial. Current evidence demonstrates that women with
hypertensive disorders of pregnancy have 2-fold higher risk for the later development of CV disease (CVD)
compared to women with healthy pregnancies. CVD prevention is a high priority for women’s health, as it is the
leading cause of death among women in the United States. In order to improve women’s CV health,
interventions for CV prevention could be initiated shortly after a pregnancy complicated by a hypertensive
disorder. However, few researchers are trained in developing patient-centered interventions to promote
preventive care engagement among postpartum women. Dr. Theilen’s objective is to address current gaps in
knowledge regarding needs, values, and barriers regarding CVD prevention among postpartum women with
hypertensive disorders of pregnancy, and to remedy the lack of available evidence-based interventions for this
at-risk population. She proposes the following Specific Aims: Aim 1) Determine information needs, values,
and barriers influencing CV risk communication and engagement among postpartum women and their obstetric
and primary care providers; Aim 2) Develop a decision aid to improve patient CV risk knowledge and
preventive health engagement for postpartum women with hypertensive disorders of pregnancy; and Aim 3)
Conduct a pilot study to demonstrate feasibility and preliminary efficacy of a patient decision aid to improve
patient knowledge and self-efficacy regarding CVD prevention during the postpartum period. The proposed
research is significant because it investigates a strategy to reduce the CVD burden among women with
hypertensive disorders of pregnancy. This proposal is innovative because it comprises a substantial departure
from the existing postpartum clinical care paradigm in the United States.
项目总结/摘要
这是一个K23的建议,博士劳伦泰伦,母胎医学医生与专业知识,在长期
妊娠期高血压疾病后的孕产妇健康。为了研究改进的策略,
心血管(CV)健康的妇女后,复杂的怀孕,这K23将允许博士Theilen
在四个职业发展领域获得关键技能:1)定性和混合方法研究方法;
2)开发和完善患者决策辅助工具; 3)设计和开展临床试验;以及4)
研究领导和管理技能。为了实现她的目标,泰伦博士组建了一个
由Michael Varner博士(初级导师)、高级研究员和
公认的围产期临床试验领导者,和三位共同导师:Bob银博士,一位有成就的研究人员
在怀孕领域作为未来健康的窗口,苏珊Zickmund博士,在定性和混合专家
方法研究,以及Elissa Ozanne博士,患者风险沟通和决策的主要研究者
发展援助。作为对这一指导团队的补充,Theilen博士还有一个由3名成员组成的咨询委员会,
支持她提出的决定援助发展和试点试验。目前的证据表明,
妊娠期高血压疾病发生CV疾病(CVD)的风险增加2倍
与健康怀孕的女性相比。心血管疾病的预防是妇女健康的一个高度优先事项,因为它是
是美国女性死亡的主要原因。为了改善女性的CV健康,
在妊娠合并高血压疾病后不久,
disorder.然而,很少有研究人员接受过以患者为中心的干预措施的培训,
产后妇女的预防保健参与。泰伦博士的目标是解决目前的差距,
产后妇女对心血管疾病预防的需求、价值观和障碍的认识
妊娠期高血压疾病,并弥补缺乏基于证据的干预措施,
高危人群。她提出了以下具体目标:目标1)确定信息需求,价值观,
以及影响产后妇女及其产科医生之间心血管风险沟通和参与的障碍
和初级保健提供者;目标2)开发决策辅助工具,以提高患者的CV风险知识,
为患有妊娠期高血压疾病的产后妇女提供预防性保健服务;以及目标3)
进行试点研究,以证明患者决策辅助的可行性和初步疗效,以改善
产后期间患者对心血管疾病预防的知识和自我效能。拟议
这项研究意义重大,因为它调查了一项减少患有心血管疾病的妇女的心血管疾病负担的战略。
妊娠期高血压疾病。这项建议是创新的,因为它大大偏离了
从美国现有的产后临床护理模式。
项目成果
期刊论文数量(2)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Cardiovascular morbidity and mortality following hypertensive disorders of pregnancy.
妊娠期高血压疾病后的心血管发病率和死亡率。
- DOI:10.1016/j.preghy.2024.101122
- 发表时间:2024
- 期刊:
- 影响因子:0
- 作者:Theilen,LaurenH;Varner,MichaelW;Esplin,MSean;Horne,BenjaminD
- 通讯作者:Horne,BenjaminD
Hypertensive disorders of pregnancy pre- and postaspirin guideline publication in individuals with pregestational diabetes mellitus.
妊娠前糖尿病患者服用阿司匹林前后的妊娠高血压疾病指南出版。
- DOI:10.1016/j.ajogmf.2023.100877
- 发表时间:2023
- 期刊:
- 影响因子:6.3
- 作者:Bruno,AnnM;Allshouse,AmandaA;Metz,TorriD;Theilen,LaurenH
- 通讯作者:Theilen,LaurenH
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{{ truncateString('Lauren Theilen', 18)}}的其他基金
Optimizing Cardiovascular Preventive Care for Women following Hypertensive Disorders of Pregnancy.
优化妊娠期高血压疾病女性的心血管预防护理。
- 批准号:
10449470 - 财政年份:2022
- 资助金额:
$ 17.71万 - 项目类别:
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$ 17.71万 - 项目类别:
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