Optimizing Cardiovascular Preventive Care for Women following Hypertensive Disorders of Pregnancy.

优化妊娠期高血压疾病女性的心血管预防护理。

• 批准号: 10449470
• 负责人: Lauren Theilen
• 金额: $ 17.71万
• 依托单位: UNIVERSITY OF UTAH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10449470
• 关键词: Address; Advisory Committees; Affect; Age; American Heart Association; Area; Attitude; Cardiovascular Diseases; Cardiovascular system; Caring; Cause of Death; Cessation of life; Client satisfaction; Clinical; Clinical Trials; Communication; Complement; Conduct Clinical Trials; Data; Decision Aid; Decision Making; Development; Discipline of obstetrics; Disease; Event; Evidence based intervention; Future; Goals; Health; Heart Diseases; Hypertension; Incidence; Intervention; Interview; K-Series Research Career Programs; Knowledge; Leadership; Learning; Life; Longevity; Maternal Health; Maternal-fetal medicine; Mentors; Outcome; Patient Education; Patient risk; Patient-Focused Outcomes; Patients; Perinatal; Persons; Physicians; Pilot Projects; Populations at Risk; Positioning Attribute; Postpartum Period; Postpartum Women; Pregnancy; Pregnancy Complications; Prevention; Preventive; Preventive care; Process; Provider; Recommendation; Research; Research Methodology; Research Personnel; Risk; Risk Factors; Self Care; Self Efficacy; Silver; Specialist; Stroke; Structure; Symptoms; Testing; Training; United States; Woman; Women' s Health; Work; base; burden of illness; cardiovascular disorder risk; cardiovascular health; cardiovascular risk factor; care providers; career; career development; clinical care; communication aid; design; disability; disorder prevention; disorder risk; efficacy testing; evidence base; healthy pregnancy; high risk; improved; innovation; lifetime risk; member; men; obstetric care; patient engagement; patient oriented; pilot trial; pregnancy disorder; prevent; programs; prototype; reproductive; skills; standard care; therapy design; tool; trial comparing; trial design

PROJECT SUMMARY/ABSTRACT This is a K23 proposal for Dr. Lauren Theilen, a Maternal-Fetal Medicine physician with expertise in long-term maternal health following hypertensive disorders of pregnancy. In order to investigate strategies for improved cardiovascular (CV) health among women following complicated pregnancy, this K23 will allow Dr. Theilen to acquire critical skills in four career development areas: 1) qualitative and mixed methods research approaches; 2) development and refinement of a patient decision aid; 3) design and conduct of clinical trials; and 4) research leadership and management skills. To achieve her goals, Dr. Theilen has assembled an interdisciplinary mentoring team comprised of Dr. Michael Varner (Primary Mentor), a senior investigator and recognized leader in perinatal clinical trials, and three Co-Mentors: Dr. Bob Silver, an accomplished researcher in the field of pregnancy as a window to future health, Dr. Susan Zickmund, an expert in qualitative and mixed methods research, and Dr. Elissa Ozanne, a leading investigator in patient risk communication and decision aid development. Complementing this mentoring team, Dr. Theilen also has a 3-member advisory committee to support her proposed decision aid development and pilot trial. Current evidence demonstrates that women with hypertensive disorders of pregnancy have 2-fold higher risk for the later development of CV disease (CVD) compared to women with healthy pregnancies. CVD prevention is a high priority for women’s health, as it is the leading cause of death among women in the United States. In order to improve women’s CV health, interventions for CV prevention could be initiated shortly after a pregnancy complicated by a hypertensive disorder. However, few researchers are trained in developing patient-centered interventions to promote preventive care engagement among postpartum women. Dr. Theilen’s objective is to address current gaps in knowledge regarding needs, values, and barriers regarding CVD prevention among postpartum women with hypertensive disorders of pregnancy, and to remedy the lack of available evidence-based interventions for this at-risk population. She proposes the following Specific Aims: Aim 1) Determine information needs, values, and barriers influencing CV risk communication and engagement among postpartum women and their obstetric and primary care providers; Aim 2) Develop a decision aid to improve patient CV risk knowledge and preventive health engagement for postpartum women with hypertensive disorders of pregnancy; and Aim 3) Conduct a pilot study to demonstrate feasibility and preliminary efficacy of a patient decision aid to improve patient knowledge and self-efficacy regarding CVD prevention during the postpartum period. The proposed research is significant because it investigates a strategy to reduce the CVD burden among women with hypertensive disorders of pregnancy. This proposal is innovative because it comprises a substantial departure from the existing postpartum clinical care paradigm in the United States.

项目摘要/摘要 这是一份针对Lauren Theilen博士的K23建议书，Lauren Theilen博士是一名母胎医学医生，在长期治疗方面具有专业知识 妊娠高血压疾病后的孕产妇健康。为了研究改进的策略 复杂妊娠后女性的心血管(CV)健康，这款K23将使泰伦博士能够 掌握四个职业发展领域的关键技能：1)定性和混合方法研究方法； 2)开发和完善患者决策辅助工具；3)设计和进行临床试验；以及4) 研究领导力和管理技能。为了实现她的目标，泰伦博士组装了一个 由Michael Varner博士(初级导师)、一名高级调查员和 围产期临床试验公认的领导者和三位共同导师：鲍勃·西尔弗博士，一位有成就的研究人员 在怀孕领域作为未来健康的窗口，苏珊·齐克蒙德博士，定性和混合方面的专家 方法研究和Elissa Ozanne博士，患者风险沟通和决策方面的领先研究员 援助发展。作为对这个指导团队的补充，泰伦博士还有一个由3名成员组成的咨询委员会，以 支持她提出的决策辅助开发和试点试验。目前的证据表明，患有癌症的女性 妊娠期高血压疾病导致心血管疾病(CVD)的风险增加2倍 与健康怀孕的女性相比。预防心血管疾病是妇女健康的高度优先事项，因为它是 这是美国女性的主要死因。为了改善女性的简历健康， 预防心血管疾病的干预措施可以在妊娠合并高血压后不久开始。 无序。然而，很少有研究人员接受过开发以患者为中心的干预措施的培训，以促进 产后妇女的预防性护理参与度。泰伦博士的目标是解决目前在 产后妇女对心血管疾病预防的需求、价值和障碍的知识 妊娠高血压疾病，并弥补对此缺乏现有的循证干预措施 高危人群。她提出了以下具体目标：目标1)确定信息需求、价值、 以及影响产后妇女及其产科妇女的心血管风险沟通和参与的障碍 和初级保健提供者；目标2)开发决策辅助工具，以提高患者简历风险知识和 为患有妊娠期高血压疾病的产后妇女提供预防性保健服务；目标3) 进行一项先导性研究，以证明患者决策辅助工具的可行性和初步效果 产后患者对心血管疾病预防的知识和自我效能。建议数 这项研究意义重大，因为它调查了一种战略，以减轻患有心血管疾病的女性的负担 妊娠高血压疾病。这项提议是创新的，因为它包含了一项重大的创新 来自美国现有的产后临床护理模式。