Core 1: Administration

核心 1：管理

• 批准号: 10631158
• 负责人: HAIAN FU
• 金额: $ 15.94万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-01 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10631158
• 关键词: Advocate; Award; Basic Cancer Research; Bioinformatics; Biology; Biostatistics Core; Cancer Center; Clinical Investigator; Clinical Trials; Collaborations; Communication; Consultations; Data; Decision Making; Ensure; Ethics; Evaluation; Evaluation Research; Funding; Future; Goals; Grant; Human Resources; Immunotherapy; Individual; Institution; Interdisciplinary Study; Leadership; Lung Adenocarcinoma; Maintenance; Malignant neoplasm of lung; Monitor; National Cancer Institute; Office of Administrative Management; Patients; Performance; Policies; Preparation; Procedures; Productivity; Program Research Project Grants; Progress Reports; Quality Control; Recommendation; Regulation; Reporting; Research; Resistance; Resource Sharing; Resources; STK11 gene; Schedule; Science; Strategic Planning; Therapeutic; Training; Translating; United States National Institutes of Health; Universities; clinical translation; data quality; experience; experimental study; improved; interdisciplinary approach; lectures; meetings; member; operation; programs; quality assurance; recruit; remediation; success; symposium

SUMMARY Vital to the success of the Lung Cancer P01, the overall goal of the Administrative Core is to provide leadership and coordination of all scientific activities, as well as fiscal management and general administrative activities in order to maximize the integrated performance of the Emory University Lung Cancer P01. The Administrative Core will be led by Drs. Haian Fu, Suresh Ramalingam and Adam Marcus, whose varied experience and expertise in the successful and productive management of individual and large multi- disciplinary research programs combines the perspectives of a basic research cancer pharmacologist with a translational clinical investigator and an expert in LKB1 biology in order to streamline and ensure high-quality decision-making for the P01. The Administrative Core will provide three distinct specific functions: (1) administration (2) coordination (3) monitoring and implementation. Administrative functions will include oversight of all Project and Core activities, fiscal oversight, provision of the necessary resources, acquisition and allocation of institutional support, preparation of annual progress reports and other documents. Coordination functions will include planning and scheduling of monthly program meetings and regular advisory board meetings, engagement of advisory board members including patient advocates, coordination of interactions between Projects, Cores and between the P01 and the Cancer Center, communication and consultation with NCI project officer and staff, organization of P01-sponsored lectures and symposia. Monitoring and implementation will include regular tracking and evaluation of research progress and data quality for all projects and cores, implementation of advisors’ recommendations, remediation of under-performing projects, and assuring compliance with all governmental, NCI, and local regulations and requirements. Guided by the P01 Executive Committee, comprised of Program, Project and Core leaders, as well as engaged advisory boards, the Administrative Core will facilitate intra-programmatic collaborations and integration of the projects and cores to result in a unified multidisciplinary approach focused on exploiting our improved understanding of LKB1-associated immunotherapy resistance in lung adenocarcinoma and translating these studies into current and future therapeutic opportunities.

概括 对于肺癌 P01 的成功至关重要，行政核心的总体目标是提供 领导和协调所有科学活动以及财务管理和一般行政 活动，以最大限度地提高埃默里大学肺癌 P01 的综合表现。这 行政核心将由博士领导。 Haian Fu、Suresh Ramalingam 和 Adam Marcus，他们的不同 在个人和大型企业的成功和富有成效的管理方面拥有丰富的经验和专业知识 学科研究项目将基础研究癌症药理学家的观点与 转化临床研究者和 LKB1 生物学专家，以简化并确保高质量 P01 的决策。 行政核心将提供三个不同的具体职能：(1) 管理 (2) 协调 (3) 监督和实施。行政职能将包括监督所有项目和核心活动， 财政监督、提供必要的资源、获取和分配机构支持、 准备年度进度报告和其他文件。协调职能将包括规划和 每月计划会议和定期顾问委员会会议的安排、顾问委员会的参与 包括患者倡导者在内的成员，协调项目、核心之间以及项目之间的互动 P01 与癌症中心、NCI项目官员及工作人员沟通协商、组织 P01 赞助的讲座和研讨会。监测和实施将包括定期跟踪和 评估所有项目和核心的研究进展和数据质量，实施顾问的建议 建议、对表现不佳的项目进行补救，并确保遵守所有政府、 NCI 以及当地法规和要求。 由 P01 执行委员会指导，由计划、项目和核心领导者以及 行政核心将促进计划内的合作和 项目和核心的整合，形成统一的多学科方法，重点是利用我们的 提高对肺腺癌中 LKB1 相关免疫治疗耐药性的了解 将这些研究转化为当前和未来的治疗机会。