Developmental Research Program

发展研究计划

• 批准号: 10210204
• 负责人: HAIAN FU
• 金额: $ 8.98万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-10 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10210204
• 关键词: American Cancer Society; Award; Clinical Research; Collaborations; Development; Evolution; Extramural Activities; Fostering; Foundations; Funding; Future; Goals; Grant; Head and Neck Cancer; Institutes; Institution; Malignant Neoplasms; Malignant neoplasm of lung; Medical; Monitor; Nature; Outcome; Patient Care; Peer Review; Peer Review Grants; Pilot Projects; Process; Program Research Project Grants; Publications; Request for Proposals; Research; Research Personnel; Research Project Grants; Research Proposals; Series; Source; Translational Research; United States National Institutes of Health; Universities; anticancer research; career development; high reward; high risk; innovation; novel; preclinical study; programs; success; translational study

PROJECT SUMMARY/ABSTRACT Emory University’s Lung Cancer SPORE aims to pursue new and innovative research opportunities in the lung cancer field through the implementation of the Developmental Research Program (DRP). The DRP will solicit, evaluate, and fund the most meritorious pilot projects, monitor progress twice annually, and promote the most successful pilot projects into full projects funded by the SPORE and/or other sources. The goals of the DRP are to identify and support meritorious proposals that might expand into full research projects focused on lung cancer in the future, including those of high risk-high reward projects that might otherwise not be funded; to foster collaborative research between Emory investigators and investigators at other institutions; and to enhance translational research in lung cancer by increasing the number of investigators working in this field. The Winship Cancer Institute (Winship) of Emory University has a strong track record in conducting successful pilot project programs. Through the Winship Invest$ program, Winship has awarded 165 pilot grants, with a total of over $7.7M in funding, since 2012. Our track record is illustrated by the DRP in Emory’s head and neck cancer SPORE (funded from 2006-2013) that awarded 17 pilot projects, which evolved into 15 full projects funded by NIH or foundations such as the American Cancer Society and the publication of 34 research articles and 4 review articles. Winship is also a recipient of the ‘Institutional Research Grant’ funded by the American Cancer Society that supports pilot research projects. Specific aims for the DRP are as follows: Aim 1: To solicit research proposals by sending request for proposals (RFP) to all possible applicants at Emory University and other research and medical institutions throughout the state of Georgia; Aim 2: To identify the most outstanding and novel proposals to fund through a clearly defined and well-established review process. Led by a DRP Committee, applications will be reviewed by a panel of leaders of all projects, cores/programs, and other researchers in relevant fields, following NIH review criteria; and Aim 3: To monitor the progress of funded peer-reviewed pilot projects using a series of metrics, including the evolution of projects into major projects (e.g., R01s, full SPORE projects), publications, investigator career development etc. We expect that annually 2 novel projects in basic, translational and clinical studies will be funded, and completion of these high-risk but innovative studies will result in strong publications, additional peer-reviewed grants and the development of a larger and stronger group of investigators focusing on the translational study of lung cancer.

项目总结/摘要 埃默里大学的肺癌孢子旨在追求新的和创新的研究机会，在肺 通过实施发展研究计划（DRP），癌症领域。DRP将征求， 评估和资助最有价值的试点项目，每年两次监测进展情况， 成功的试点项目转化为由SPORE和/或其他来源资助的全面项目。DRP的目标 是确定和支持有价值的建议，可能扩大到全面的研究项目，重点是肺 未来的癌症，包括那些高风险高回报的项目，否则可能不会得到资助; 促进埃默里大学研究人员与其他机构研究人员之间的合作研究; 通过增加在该领域工作的研究人员的数量来加强肺癌的转化研究。 埃默里大学的Winship癌症研究所（Winship）在进行成功的 试点项目方案。通过Winship Invest$计划，Winship已授予165个试点赠款， 自2012年以来，共筹集资金770多万美元。我们的跟踪记录是由在埃默里的头部和颈部的DRP说明 癌症孢子（2006-2013年资助），授予17个试点项目，发展成为15个完整的项目 由NIH或美国癌症协会等基金会资助，并发表了34篇研究文章 4篇评论文章Winship也是美国政府资助的“机构研究资助”的获得者。 癌症协会支持试点研究项目。难民遣返方案的具体目标如下：目标1： 通过向埃默里大学所有可能申请人发送征求建议书（RFP）来征求研究建议 整个格鲁吉亚州的大学和其他研究和医疗机构;目标2： 通过一个明确界定和完善的审查程序，为最杰出和新颖的提案提供资金。 在DRP委员会的领导下，申请将由所有项目、核心/计划的领导人组成的小组进行审查， 和相关领域的其他研究人员，遵循NIH审查标准;目标3：监测 使用一系列衡量标准资助同行评审的试点项目，包括项目演变为重大项目， 项目（例如，R 01、完整的SPORE项目）、出版物、研究者职业发展等。我们希望 每年将资助2个基础、转化和临床研究的新项目，并完成这些项目。 高风险但创新的研究将导致强大的出版物，额外的同行评审赠款和 发展一个更大更强的研究小组，专注于肺癌的转化研究。