Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial Approach
城市人畜共患流行病的控制和预防:社会空间方法
基本信息
- 批准号:10629256
- 负责人:
- 金额:$ 13.08万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2019
- 资助国家:美国
- 起止时间:2019-06-01 至 2025-05-31
- 项目状态:未结题
- 来源:
- 关键词:AffectAlgorithmsAnimalsAreaBehaviorBiological ModelsCanis familiarisCitiesCommunitiesComplexDataDiseaseDomestic AnimalsEcologyEnvironmentEpidemicFailureFocus GroupsGeographyHealthHealth ServicesHealth behaviorHeterogeneityHumanIndividualInterviewLatin AmericaLocationLogistic RegressionsMass VaccinationsMathematicsMeasuresMethodologyMethodsModelingMovementPeruPopulationPopulation DensityPopulation DynamicsPopulation HeterogeneityPreventionPublic HealthRNA InterferenceRabiesRabies VaccinesRabies virusResearchRisk ReductionRoleRuralRural CommunitySeasonal VariationsStatistical ModelsSurveysTestingUnited States Public Health ServiceUrban PopulationUrbanizationVaccinatedVaccinationVaccinesVariantWorkZoonosescommunity-level factordesigndisorder controlepidemic responseexperienceexperimental studyfeasibility testinghealth service useimprovedinfection riskinnovationinterdisciplinary approachmathematical algorithmmathematical modelmembermigrationmultidisciplinarynovel strategiespathogenpreventprogramssocialsocial determinantssocial factorstransmission processunvaccinateduptakeurban areaurban settingvaccine acceptanceviral transmission
项目摘要
Project Summary
Zoonotic diseases present unique challenges for public health due to the complex interactions between
humans, animals, pathogens, and the environment. Urbanization, migration, and the urban landscape add
additional layers of complexity to these interactions, and the control and prevention of zoonotic pathogens
requires innovative multidisciplinary methodological approaches that take into account social, spatial and
population dynamics in urban areas.
Epidemics of zoonotic pathogens are ongoing in major urban centers across Latin America and
worldwide, and among them, the city of Arequipa, Peru is in the midst of a canine rabies epidemic. The drivers
of this epidemic work at many levels: Individual- and community-level factors, including social determinants,
may explain the currently low vaccination rate of domestic animals against rabies. Urban geography can also
affect participation in zoonotic disease control programs, facilitating the emergence of canine rabies and
complicating its control. Free-roaming owned and stray dogs with their unique ecology and population
dynamics could also impact the results of control activities. In this proposal I will develop a new approach for
the control and prevention of zoonotic disease in cities that integrates mathematical and social approaches,
using rabies as a model zoonotic disease strongly determined by urban dynamics.
Following the urban re-emergence after 15 years, the Ministry of Health has failed to quell the rabies
epidemic in Arequipa's complex urban environment. I hypothesize that the failure is due primarily to three
factors: 1) Poorly understood determinants of canine vaccination uptake; 2) Ignored spatial heterogeneity of
unvaccinated dogs, especially stray dogs; and, 3) Suboptimal placement of vaccine tents across the urban
landscape.
Under a first aim, a qualitative study and a survey are proposed to identify social and spatial
determinants of canine vaccination uptake in urban settings. The second aim will evaluate mathematically
different strategies that consider the role of stray dogs in rabies control programs. Finally, the third aim will
incorporate social and spatial factors into a mathematical algorithm to optimize the location of vaccine tents.
For this third study, a discrete-choice experiment will be performed to test the acceptability of the optimized
vaccine stand placements.
This proposal aims to produce an urgently needed novel approach for zoonotic disease control programs in
cities to integrate urban landscapes, health behaviors, diverse populations, and optimal placement of health
service facilities.
项目总结
项目成果
期刊论文数量(11)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Do Incentives Crowd Out Motivation? A Feasibility Study of a Community Vector-Control Campaign in Peru.
激励措施会排挤动力吗?
- DOI:10.1080/08964289.2021.1977603
- 发表时间:2023
- 期刊:
- 影响因子:0
- 作者:Buttenheim,AlisonM;Castillo-Neyra,Ricardo;Arevalo-Nieto,Claudia;Shinnick,JuliannaE;Sheen,JustinK;Volpp,KevinG;Paz-Soldan,Valerie;Behrman,JereR;Levy,MichaelZ
- 通讯作者:Levy,MichaelZ
Socio-Demographic Determinants Associated with Blastocystis Infection in Arequipa, Peru.
- DOI:10.4269/ajtmh.20-0631
- 发表时间:2020-11-16
- 期刊:
- 影响因子:0
- 作者:Salazar-Sánchez RS;Ascuña-Durand K;Ballón-Echegaray J;Vásquez-Huerta V;Martínez-Barrios E;Castillo-Neyra R
- 通讯作者:Castillo-Neyra R
Dog Population Rabies Immunity before a Mass Vaccination Campaign in Lima, Peru: Vulnerabilities for Virus Reestablishment.
- DOI:10.4269/ajtmh.22-0530
- 发表时间:2023-08-02
- 期刊:
- 影响因子:0
- 作者:Chuquista-Alcarraz O;Falcón N;Vigilato MAN;Rocha F;Toledo-Barone G;Amorim-Conselheiro J;Recuenco SE;Castillo-Neyra R
- 通讯作者:Castillo-Neyra R
The Amazonian Tropical Bites Research Initiative, a hope for resolving zoonotic neglected tropical diseases in the One Health era.
- DOI:10.1093/inthealth/ihac048
- 发表时间:2023-03-01
- 期刊:
- 影响因子:2.5
- 作者:Taylor, Emma;Gladys Aguilar-Ancori, Elsa;Banyard, Ashley C.;Abel, Isis;Mantini-Briggs, Clara;Briggs, Charles L.;Carrillo, Carolina;Gavidia, Cesar M.;Castillo-Neyra, Ricardo;Parola, Alejandro D.;Villena, Fredy E.;Prada, Joaquin M.;Petersen, Brett W.;Falcon Perez, Nestor;Cabezas Sanchez, Cesar;Sihuincha, Moises;Streicker, Daniel G.;Maguina Vargas, Ciro;Navarro Vela, Ana Maria;Vigilato, Marco A. N.;Fan, Hui Wen;Willoughby, Rodney;Horton, Daniel L.;Recuenco, Sergio E.
- 通讯作者:Recuenco, Sergio E.
Relative Frequency of Blastocystis Subtypes 1, 2, and 3 in Urban and Periurban Human Populations of Arequipa, Peru.
秘鲁阿雷基帕市的城市和城市人口中,胚泡亚型1、2和3的相对频率。
- DOI:10.3390/tropicalmed5040178
- 发表时间:2020-11-27
- 期刊:
- 影响因子:2.9
- 作者:Ascuña-Durand K;Salazar-Sánchez RS;Castillo-Neyra R;Ballón-Echegaray J
- 通讯作者:Ballón-Echegaray J
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Ricardo Castillo Neyra其他文献
Ricardo Castillo Neyra的其他文献
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{{ truncateString('Ricardo Castillo Neyra', 18)}}的其他基金
Spatially responsive mass vaccination strategies for urban rabies
城市狂犬病的空间响应大规模疫苗接种策略
- 批准号:
10606567 - 财政年份:2022
- 资助金额:
$ 13.08万 - 项目类别:
Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial Approach
城市人畜共患流行病的控制和预防:社会空间方法
- 批准号:
9920085 - 财政年份:2019
- 资助金额:
$ 13.08万 - 项目类别:
Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial Approach
城市人畜共患流行病的控制和预防:社会空间方法
- 批准号:
10417075 - 财政年份:2019
- 资助金额:
$ 13.08万 - 项目类别:
Control and Prevention of Zoonotic Epidemics in Cities: A Socio-Spatial Approach
城市人畜共患流行病的控制和预防:社会空间方法
- 批准号:
10180891 - 财政年份:2019
- 资助金额:
$ 13.08万 - 项目类别:
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