Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products
动物标本和大麻基动物饲料产品中大麻素分析的方法验证
基本信息
- 批准号:10668979
- 负责人:
- 金额:$ 7.6万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2020
- 资助国家:美国
- 起止时间:2020-08-01 至 2024-07-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Project Summary
The purpose of this application is develop and validate the analysis of cannabinoids in hemp-
derived food products as well as in animal specimen. The 2014 Farm Bill legalized the cultivation
and production of industrial hemp (Cannabis sativa containing < 0.3%Tetrahydrocannabinol) and
the removal of industrial hemp as DEA Schedule I drug. More recently, the 2018 Farm Bill has
allowed for increased interest in hemp cultivation as a novel agricultural commodity under certain
provisions. Hemp plants and their by-products, are considered to have nutritional and potentially
therapeutic value when used as a feed source in livestock. Many commercially available hemp
oils and feed product are available on the market with little information of their cannabinoids
content. In addition, there is a need to develop a cannabinoid screen in animal specimen as little
is known about their distribution in cattle following oral administration and the time required for
depletion in edible tissues. There is also a need to have a diagnostic test available in the
toxicology laboratory as pets are regularly intoxicated with cannabis-derived products: in this
case, plasma and urine would be specimen of choice to detect exposure to THC. The outcomes
will include: 1) the broadening capacity of the FDA to investigate animal food or drug related
concerns, 2) an Increased capacity to respond to large-scale animal food/feed emergency events,
3) the improvement in the quality and standardization of Federal and State surveillance of animal
food and feed. We already have experience in quantifying cannabinoids in oil and hemp-based
supplements and have started to work on developing the method in bovine plasma.
项目摘要
该应用程序的目的是开发和验证大麻中大麻素的分析,
衍生食品以及动物标本中。2014年农业法案将种植合法化
和生产工业大麻(大麻含有<0.3%的四氢大麻酚),
将工业大麻从DEA一级药物名单中移除最近,2018年农业法案
允许增加大麻种植的兴趣,作为一种新的农业商品,在某些情况下,
条文大麻植物及其副产品,被认为具有营养和潜在的
当用作牲畜的饲料来源时具有治疗价值。许多市售大麻
市场上可获得的油和饲料产品很少有关于其大麻素的信息
内容此外,需要在动物标本中开发大麻素筛选,
已知经口给药后其在牛中的分布以及
可食用组织中的损耗。还需要有一个诊断测试,
毒理学实验室,因为宠物经常与大麻衍生产品中毒:在这个
在这种情况下,血浆和尿液将是检测THC暴露的首选标本。成果
将包括:1)扩大FDA调查动物食品或药物相关的能力
2)提高应对大规模动物食品/饲料紧急事件的能力,
3)提高联邦和州动物监测的质量和标准化
食物和饲料。我们已经有了量化大麻素的经验,
补充剂,并已开始在牛血浆中开发该方法。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
数据更新时间:{{ journalArticles.updateTime }}
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
数据更新时间:{{ journalArticles.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ monograph.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ sciAawards.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ conferencePapers.updateTime }}
{{ item.title }}
- 作者:
{{ item.author }}
数据更新时间:{{ patent.updateTime }}
Steven M Ensley其他文献
Steven M Ensley的其他文献
{{
item.title }}
{{ item.translation_title }}
- DOI:
{{ item.doi }} - 发表时间:
{{ item.publish_year }} - 期刊:
- 影响因子:{{ item.factor }}
- 作者:
{{ item.authors }} - 通讯作者:
{{ item.author }}
{{ truncateString('Steven M Ensley', 18)}}的其他基金
Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products
动物标本和大麻基动物饲料产品中大麻素分析的方法验证
- 批准号:
10085972 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别:
Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products
动物标本和大麻基动物饲料产品中大麻素分析的方法验证
- 批准号:
10468637 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别:
Method validation for the analysis of cannabinoids in animal specimen and hemp-based animal feed products
动物标本和大麻基动物饲料产品中大麻素分析的方法验证
- 批准号:
10213750 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别:
KSVDL Vet-LRN Veterinary Diagnostic Laboratory Program
KSVDL Vet-LRN 兽医诊断实验室计划
- 批准号:
10415847 - 财政年份:2018
- 资助金额:
$ 7.6万 - 项目类别:
KSVDL Vet-LRN Veterinary Diagnostic Laboratory Program
KSVDL Vet-LRN 兽医诊断实验室计划
- 批准号:
10188538 - 财政年份:2018
- 资助金额:
$ 7.6万 - 项目类别:
相似海外基金
FastPlex: A Fast Deep Learning Segmentation Method for Accurate Choroid Plexus Morphometry
FastPlex:一种用于精确脉络丛形态测量的快速深度学习分割方法
- 批准号:
10734956 - 财政年份:2023
- 资助金额:
$ 7.6万 - 项目类别:
CRSNS: Development of EEG/MEG Source Reconstruction with Fast Multipole Method
CRSNS:使用快速多极方法进行 EEG/MEG 源重建的开发
- 批准号:
10835137 - 财政年份:2023
- 资助金额:
$ 7.6万 - 项目类别:
Rapid NGS Method for Mapping of the Epitranscriptome
表观转录组图谱快速 NGS 方法
- 批准号:
10697296 - 财政年份:2022
- 资助金额:
$ 7.6万 - 项目类别:
Method for the validation by Western analysis of affinity reagents against post-translationally modified proteins.
通过蛋白质印迹分析验证亲和试剂针对翻译后修饰蛋白质的方法。
- 批准号:
10819809 - 财政年份:2022
- 资助金额:
$ 7.6万 - 项目类别:
Dissecting the sensory hair cell nucleus: Development of a novel method for investigating chromatin interactions (Tn5-Capture) in small cell numbers
解剖感觉毛细胞核:开发一种研究小细胞中染色质相互作用(Tn5-Capture)的新方法
- 批准号:
10571130 - 财政年份:2022
- 资助金额:
$ 7.6万 - 项目类别:
Improving the Risk Adjustment Method for Quality Care Measures through Application of an Innovative Individual-Level Socioeconomic Measure
通过应用创新的个人层面的社会经济措施,改进优质护理措施的风险调整方法
- 批准号:
10213256 - 财政年份:2021
- 资助金额:
$ 7.6万 - 项目类别:
Improving the Risk Adjustment Method for Quality Care Measures through Application of an Innovative Individual-Level Socioeconomic Measure
通过应用创新的个人层面的社会经济措施,改进优质护理措施的风险调整方法
- 批准号:
10394328 - 财政年份:2021
- 资助金额:
$ 7.6万 - 项目类别:
Developing a high-throughput method to validate microRNA biogenesis in vivo.
开发一种高通量方法来验证 microRNA 体内生物发生。
- 批准号:
10210415 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别:
Developing a high-throughput method to validate microRNA biogenesis in vivo.
开发一种高通量方法来验证 microRNA 体内生物发生。
- 批准号:
10043005 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别:
Development of a noninvasive, rapid and affordable method for early detection of colorectal cancer
开发一种无创、快速且经济实惠的结直肠癌早期检测方法
- 批准号:
10044350 - 财政年份:2020
- 资助金额:
$ 7.6万 - 项目类别: