Research Core 2: Health and Mobility Measures Core (RC2)

研究核心 2：健康和流动性措施核心 (RC2)

• 批准号: 10670276
• 负责人: Katherine Shepherd Hall
• 金额: $ 21.74万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-09-15 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10670276
• 关键词: Aging; American; Applications Grants; Area; Biological Markers; Capsicum; Clinical Research; Cognitive; Communities; Consultations; Data; Data Collection; Data Science; Data Set; Data Sources; Development; Devices; Doctor of Philosophy; Educational workshop; Elderly; Electronic Health Record; Ensure; Equipment; Exercise; Funding; Future; Grant; Health; Health Status; Healthcare; Human Resources; International; Intervention; Investigation; Longevity; Manuscripts; Measurement; Measures; Mentors; Mission; Molecular; Monitor; Outcome; Patient Self-Report; Performance; Personal Satisfaction; Persons; Phase; Physical Performance; Physiological; Pilot Projects; Preparation; Protocols documentation; Publishing; Reproducibility; Research; Research Design; Research Personnel; Research Training; Resources; Science; Services; Standardization; Technology; Testing; Training; Translational Research; Work; biomarker performance; cognitive reserve; community engagement; dashboard; data integration; data visualization; design; education research; experience; health data; improved; innovation; meetings; member; multidisciplinary; population based; predictive modeling; psychosocial; research faculty; resilience; social; social health determinants; standardize measure; symposium; synergism; therapy development; translational pipeline; wearable device; web site; whole health; working group

PROJECT SUMMARY – Health and Mobility Measures Core (HMC) An important consideration for investigators undertaking studies relevant to the Center theme “To Understand and Optimize Reserve and Resilience” is how to select and implement the most appropriate and meaningful measures. The Health and Mobility Measures Core (HMC) will provide this service by serving as the central resource for Center investigators seeking advice, mentoring, training, and equipment for valid, sensitive, and reliable whole-person, non-molecular measures. A panel of 13 members, with complementary expertise in measurement across multiple domains, comprises the Core. The HMC will provide highly integrated, customized support to investigators supported by our Research Education Component (REC), Pilot/Exploratory Studies Core (PESC), External Projects (EPs), and the larger Duke Community engaged by the Duke Older Americans Independence Center. The Core will support investigators by meeting regularly, or as needed, throughout the full spectrum of project development; from early phase planning, to final interpretation of findings, to subsequent grant preparations to dissemination and/or implementation. These meetings will concurrently involve members of the Molecular Measures and Analysis Cores to ensure maximal synergy. The HMC will address three Specific Aims. Aim 1 - To provide centralized measurement expertise, available for consultation and mentoring to advance our thematic investigations of physical reserve and resilience. Aim 2 - To develop measurement protocols and train personnel in administration and data collection. Aim 3 - To identify gaps in reserve and resiliency measures and develop and/or adapt innovative new measurement approaches for related outcomes. Up to three REC Scholars and three PES awardees will be supported during the first year of funding. Members of the HMC will also provide service to EPs, and propose an innovative Developmental Project to extend measurement and predictive capacity of the electronic health record and other big administrative data sources. Two successful past workshops are proposed again; one to provide training in physical performance and functional testing, and one to provide training in ambulatory measurement and data collection, to augment the measurement capabilities of our trainees. New measures will be added to the HMC website and the Duke Pepper Center Study Dashboard will be developed and posted for users. The dashboard is an interactive data visualization dashboard that gives OAIC investigators the opportunity to interact with aggregated biomarker and physical performance data collected from OAIC-affiliated studies spanning three decades. The Dashboard will provide OAIC investigators with preliminary data to use for grant applications as well as a large, well-curated dataset for new analyses. The HMC will provide an invaluable service to the Center, which will lead to greater understanding of reserve and resilience, and which in turn, will point to opportunities to improve the current and future health and well-being of aging Americans across the lifespan.

健康和流动性措施核心（HMC） 研究人员进行与中心主题“了解 和优化储备和弹性”是如何选择和实施最适当和有意义的 措施健康和流动性措施核心（HMC）将通过作为中心提供这项服务， 中心研究人员寻求有效、敏感和 可靠的全人非分子测量一个由13名成员组成的小组，具有以下方面的互补专长： 跨多个领域的测量，包括核心。HMC将提供高度集成、定制化的 支持我们的研究教育组件（REC），试点/探索性研究核心支持的研究者 （PESC），外部项目（EP），以及由杜克老年美国人参与的更大的杜克社区 独立中心。核心将通过定期会议或根据需要在整个研究期间为研究者提供支持。 全方位的项目开发;从早期阶段的规划，到最终的结果解释，再到后续的 为传播和/或实施提供准备。这些会议将同时涉及成员 分子测量和分析核心，以确保最大的协同作用。HMC将解决三个具体问题 目标。目标1 -提供集中的测量专业知识，可用于咨询和指导， 推进我们对实物储备和复原力的专题调查。目标2 -发展计量 协议和培训管理和数据收集人员。目标3 -查明储备金缺口， 复原力措施，并为相关成果制定和/或调整创新的新衡量方法。 最多三个REC学者和三个PES获奖者将在第一年的资金支持。成员 此外，亦会为环保人士提供服务，并建议一项创新的发展计划， 电子健康记录和其他大型管理数据源的测量和预测能力。 两个成功的过去的讲习班再次提出，一个提供培训的身体表现， 功能测试，一个提供动态测量和数据收集方面的培训， 我们学员的测量能力。新的措施将被添加到HMC网站和杜克胡椒 将为用户开发并发布中心研究仪表板。仪表板是一种交互式数据 可视化仪表板，使OAIC研究人员有机会与聚合的生物标志物进行交互， 从OAIC附属研究中收集的跨越三十年的物理性能数据。信息中心会 为OAIC调查人员提供用于资助申请的初步数据，以及一个大型的，精心策划的 新的分析数据集。HMC将为中心提供宝贵的服务，这将导致更大的 了解储备和复原力，这反过来又将指出改善当前和 未来的健康和福祉的老龄美国人在整个生命周期。