Exploring strategies to restore function in older Veterans with PTSD.

探索恢复患有创伤后应激障碍 (PTSD) 的老年退伍军人功能的策略。

• 批准号: 8201483
• 负责人: Katherine Shepherd Hall
• 金额: --
• 依托单位: DURHAM VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-02-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8201483
• 关键词: Activities of Daily Living; Address; Adherence; Aging; Area; Award; Behavior; Behavior Therapy; Behavioral; Chronic; Clinical; Clinical Trials; Cognitive; Cognitive Therapy; Comorbidity; Counseling; Data; Data Set; Development; Doctor of Philosophy; Education; Elderly; Etiology; Exercise; Focus Groups; Future; Goals; Health; Health Services; Health behavior; Individual; Intervention; Knowledge; Life Style; Measures; Medical center; Mentors; Methods; Modeling; Morbidity - disease rate; Neighborhoods; Older Population; Outcome; Overweight; Paper; Participant; Pathway interactions; Physical Function; Physical activity; Pilot Projects; Population; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Productivity; Psychosocial Factor; Quality of life; Randomized; Research; Research Project Grants; Review Literature; Role; Sampling; Symptoms; Techniques; Time; Training; Veterans; Work; arm; base; behavior change; behavior influence; cohort; compare effectiveness; experience; fitness; functional outcomes; functional restoration; health related quality of life; impaired glucose tolerance; interest; knowledge base; lifestyle intervention; meetings; novel; programs; rehabilitation strategy; response; therapy design

DESCRIPTION (provided by applicant) Exploring strategies to restore function in older Veterans with PTSD. This is a submission for a CDA-1. The candidate for this award is Katherine S. Hall, Ph.D., a postdoctoral fellow at the Geriatric Research, Education, and Clinical Center of the Durham Veterans Affairs Medical Center. Dr. Miriam C. Morey will serve as a primary mentor and Drs. Jean C. Beckham and Hayden B. Bosworth will serve as co-mentors during this award. The overarching goal of this proposal is for the candidate to build a research program in the role of multiple morbidities on behavioral and functional outcomes in older adults; specifically focusing on the added burden of posttraumatic stress disorder (PTSD) in addition to chronic conditions common to older adults. Dr. Hall will explore the added burden of PTSD on adherence and longitudinal trajectories of change in physical activity behavior and functional outcomes. Dr. Hall has identified the variables of interest in an ongoing clinical trial (the Enhancing Fitness Study, Morey PI) and has performed preliminary analysis to explore the impact of PTSD on physical activity and function in a convenience sample of overweight, older Veterans, with impaired glucose tolerance. Dr. Hall's proposed mentored research seeks to extensively characterize these associations in this dataset by examining baseline associations and the effects of PTSD on changes in clinical outcomes over time. Activities under this award include identifying the barriers to physical activity unique to this population and develop cognitive-behavioral strategies to address specific barriers for older adults with multiple morbidities and PTSD. Results from these aims will inform the future development of a pilot study of a randomized, controlled exercise intervention designed to compare the effectiveness of a group-based cognitive-behavioral intervention for increasing adherence to physical activity compared to traditional behavioral interventions in this understudied, but growing, sub-population of older Veterans. Dr. Hall's training plan includes broadening and strengthening her understanding of the etiology and manifestations of PTSD, exploring the potential mechanisms by which PTSD influences physical activity participation, strengthening her background in cognitive-behavioral techniques and applying these principles to physical activity behavior, and statistical handling of longitudinal and between-group analyses. Given the candidate's strong background in physical activity and her experience with research projects in behavioral interventions and functional assessment, a strong knowledge of PTSD as a psychiatric comorbidity and further development of her cognitive-behavioral and statistical knowledge base will enhance her future productivity and potential in this competitive field. The goal is that Dr. Hall will develop a novel and unique area of research that has tremendous potential for developing rehabilitation strategies for maintaining and restoring function in a cohort with multiple morbidities that is aging and likely to impose a high functional burden on VAMC health services.

描述（由申请人提供） 探索使用PTSD恢复老年退伍军人的功能的策略。 这是CDA-1的提交。该奖项的候选人是凯瑟琳·霍尔（Katherine S. Miriam C. Morey博士将担任主要导师和博士。让·C·贝克汉姆（Jean C. Beckham）和海登·B·博斯沃思（Hayden B. 该提案的总体目标是候选人建立一项研究计划，以在老年人的行为和功能结果上发挥多种病态的作用；除了老年人常见的慢性疾病外，还专门研究了创伤后应激障碍（PTSD）的额外负担。 霍尔博士将探索PTSD对体育活动行为和功能结果变化的依从性和纵向轨迹的额外负担。霍尔博士已经确定了正在进行的临床试验（增强健身研究，莫尔·PI）中感兴趣的变量，并进行了初步分析，以探索PTSD对超重，老年退伍军人的便利样本，具有葡萄糖耐受性受损的方便样本。霍尔博士提出的指导研究旨在通过检查基线关联以及PTSD对随着时间的推移临床结果的变化来广泛地表征该数据集中的这些关联。 该奖项下的活动包括确定该人群独有的体育锻炼障碍，并制定认知行为策略，以应对多种病毒和PTSD的老年人的特定障碍。 这些目标的结果将为未来的发展研究，对一项随机，受控的运动干预措施的试点研究旨在比较基于群体的认知行为干预措施的有效性，以增加对这项研究的但不断增长但不断增长的较旧人群的传统行为干预措施的依从性。霍尔博士的培训计划包括扩大和加强她对PTSD的病因和表现的理解，探索PTSD影响体育活动参与的潜在机制，增强她在认知行为行为技术中的背景，并将这些原理应用于身体活动行为，并将其应用于较长的和长期分析的统计学处理。 鉴于候选人在体育锻炼方面的强大背景以及她在行为干预和功能评估方面的研究项目的经验，对PTSD作为精神病合并症的强大知识以及对她的认知行为和统计知识基础的进一步发展将提高她在这个竞争性领域的未来生产力和潜力。 目的是，霍尔博士将开发一个新颖而独特的研究领域，该领域具有开发康复策略的巨大潜力，以维持和恢复具有多种病毒性衰老的队列中的功能，并可能对VAMC卫生服务造成高功能负担。