Pediatric Oncology Research Training Program

项目摘要/摘要 这项跨学科的儿科肿瘤学研究培训(PORT)T32申请的目的是招募和 为儿科肿瘤学的研究密集型职业培养高素质、积极进取和多样化的医生。 多份报告强调，严重缺乏在实验室或医院受过良好培训的儿科肿瘤学家。 临床研究，那些将在该领域取得进步并成为加强治疗的下一代领导者 患有癌症的儿童。留住最优秀、最聪明的受训人员从事研究工作正变得越来越重要。我们的 PORT计划整合在我们NCI指定的癌症中心联盟中，由三个学术机构组成 合作机构：弗雷德·哈钦森癌症研究中心(FHCRC)、西雅图儿童医院(SCH)、 华盛顿大学医学院(UWSOM)。这提供了无与伦比的基础设施 在我们52年的奖学金培训计划和43年来持续资助T32的基础上再接再厉 格兰特并继续通过招募最优秀的候选人来培训未来的儿科肿瘤学领导者 并为他们配备最先进的研究工具，以确保成功过渡到 独立研究职业。本培训计划仅对医学博士或医学博士学位的申请者开放 对研究密集型职业有浓厚兴趣并提供实验室培训机会的人- 在结果/生存/健康差异研究方面的基础科学和临床研究。它为以下各项提供支持 为每年注册的2名医生/科学家提供为期2年的研究培训，这些医生/科学家已完成前12个月的学习 在我们的ACGME批准的儿科血液肿瘤学奖学金计划中进行临床培训。大多数 学员的时间花在由大学挑选的教师导师(S)的直接指导下进行研究 在一个特别选定的研究监督委员会和执行委员会的指导下 T32。我们的项目提供教学和研究设计的坚实基础，开发 学员概念化和解决研究问题的能力，鼓励提高独立性，提供 最先进的分析技术培训，要求学员在科学会议上展示他们的研究成果 会议并公布其结果，并传达对受训者研究与 健康和疾病。我们的计划由才华横溢、资金充裕、出版良好的导师组成，他们被部署在 跨越特定的研究途径，使学员接触到不同的科学问题、方法和疾病 模特们。由学者监督委员会对研究员和计划进行纵向评估，以确保 为受训人员和外部咨询委员会提供最佳培训，以帮助审查和改进方案 这是培训计划的内在要求。可利用多种机构资源来促进职业发展 允许所有受训人员制定定制的培训计划。受过该项目培训的研究人员将是特例 准备在儿科肿瘤学研究密集型环境中从事职业生涯的内科科学家，具有 在癌症生物学、诊断、预防、治疗和结果方面具有高度发达的研究技能。

PROJECT SUMMARY/ABSTRACT The aim of this inter-disciplinary Pediatric Oncology Research Training (PORT) T32 application is to recruit and prepare highly qualified, motivated, and diverse physicians for a research-intensive career in Pediatric Oncology. Multiple reports have emphasized the dire shortage of pediatric oncologists that are well trained in laboratory or clinical research, those who will advance the field and be the next generation of leaders in enhancing care of children with cancer. It is increasingly important to retain the best and brightest trainees in research careers. Our PORT Program is integrated within our NCI-designated Cancer Center Consortium, comprising three academic partner institutions: the Fred Hutchinson Cancer Research Center (FHCRC), Seattle Children’s Hospital (SCH), and the University of Washington School of Medicine (UWSOM). This provides an unparalleled infrastructure to build on the 52-year history of our fellowship training program and 43 years of continuous funding of this T32 grant and continue to train the future leaders in pediatric oncology by recruiting the candidates with the highest academic ceiling and arming them with the most advanced research tools to ensure successful transition to independent research careers. This training program is available only to MD or MD-PhD-prepared applicants who have strong interest in a research-intensive career and provides opportunities for training in laboratory- based science as well as clinical research in outcome/survivorship/health disparity research. It offers support for 2 years of research training for 2 physician/scientists enrolled each year who have completed their first 12 months of clinical training in our ACGME-approved Pediatric Hematology Oncology Fellowship Program. Most of the trainee’s time is spent conducting research under the direct supervision of a faculty mentor(s) selected by the trainee with guidance from a specially selected Research Oversight Committee and the Executive Committee of the T32. Our program provides didactic teaching and a strong foundation in research design, develops the trainees’ ability to conceptualize and solve research problems, encourages increasing independence, provides training in state-of-the-art analytical techniques, requires trainees to present their research findings at scientific meetings and publish their results, and conveys an understanding of the relationship of the trainee’s research to health and disease. Our program consists of talented, well-funded and well-published mentors who are deployed across specific research pathways to expose trainees to diverse scientific questions, methodologies, and disease models. Longitudinal evaluation of the fellows and the program by Scholar Oversight Committees to ensure optimal training for the trainee and External Advisory Committee to help review and improve the program is intrinsic to the training program. Multiple institutional resources to enhance career development are available to allow all trainees to develop a customized training plan. Researchers trained in this program will be exceptional physician-scientists who are prepared for a career in a research-intensive setting in pediatric oncology, with highly developed research skills in cancer biology, diagnosis, prevention, therapy, and outcomes.