Quantitative Bioscience Core

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PROJECT SUMMARY/ABSTRACT Core 1: Quantitative Bioscience Core The main goal of the Quantitative Bioscience Core is to provide a centralized service for biostatistics and bioinformatics needs of the program. The core will work closely with all three projects and the HPM Core to provide experimental design and multi-level omics data analysis to enable in-depth understanding of microenvironment alterations associated with adenoma progression and malignant transformation. The core will provide quality control for all animal and clinical studies, cutting edge pipelines and methods for multi-omics data analysis, and develop and evaluate novel methods for integrative single-cell and spatial transcriptomics analysis.