Multidisciplinary Research Training Program in Alzheimer's Disease and Related Disorders

项目摘要/摘要 这是来自堪萨斯大学阿尔茨海默病研究中心(KU)的T32培训补助金 ADRC)培训下一代阿尔茨海默病和相关痴呆症(ADRD)研究人员。这个 KU ADRC成立于2011年，是33个具有独特主题专长的国家研究中心之一 线粒体/生物能量学、生活方式改变和AD预防研究。北卡罗来纳大学ADRC研究基地 在过去的十年里急剧增长，现在显然需要增加它的研究培训计划 加快研究工作，造就下一代ADRD研究人员。 拟议的T32计划将为2名学生提供多学科的翻译ADRD研究培训 博士后，博士后2人，暑期学生4人。项目教职员工包括23名初级P受体，他们是 唯一有资格支持全日制(博士后和博士后实习生)和暑期实习生和19名短期实习生 有资格支持暑期学生的教师。42名教职员工来自18个系和 包括基础研究人员、翻译研究人员和临床研究人员，他们都有彼此合作的历史，并 亚洲发展研究中心。我们有一大批符合培训资助资格的学员，他们被 NIH资助的研究的多样化和不断增长的投资组合。 我们的培训方法包括针对全日制学员的双重导师计划(即基础导师和临床导师) 它被构建为个人发展计划，以鼓励多学科和翻译 接近了。该计划旨在提供发展独立研究事业所需的技能 在ADRD研究中，通过4个目标：1)提供广泛的ADRD基础，接触不同的 研究方法(基础、临床和翻译)和临床护理(患者和护理人员)，2)发展 ADRD研究技能(基础、临床和翻译)，3)发展多学科研究技能，以促进 学员和导师之间的合作，以及4)发展演讲和撰写赠款的技能。夏天 培训计划旨在让临床学生接触ADRD研究和临床护理，以培养对 从事ADRD研究的职业。 该培训计划利用机构资源和KU ADRC的研究优势，创建一个 下一代ADRD基础、翻译和临床科学家的发展道路。T32 资金将提供关键支持，以协同正在进行的机构努力，进一步加强ADRC的 培训工作，并利用该中心独特的资源、杰出的导师、支持性的合作者以及 教育机会的广度不断增加。

PROJECT SUMMARY/ABSTRACT This is a T32 training grant from the University of Kansas Alzheimer's Disease Research Center (KU ADRC) to train the next generation of researchers in Alzheimer's disease and related dementias (ADRD). The KU ADRC was funded in 2011 and is one of 33 national research centers with unique thematic expertise in mitochondria / bioenergetics, lifestyle modification, and AD prevention research. The KU ADRC research base has grown dramatically in the last decade and there is now a clear need to grow its research training programs to accelerate the research efforts and create the next generation of ADRD researchers. The proposed T32 program will provide multidisciplinary, translational ADRD research training for 2 predoctoral, 2 postdoctoral, and 4 summer students. Program faculty include 23 Primary Preceptors who are uniquely qualified to support full-time (pre- and postdoctoral trainees) and summer trainees and 19 Short-Term Preceptors who are eligible to support summer students. The 42 faculty come from 18 departments and include basic, translational, and clinical investigators who all have a history of collaboration with each other and the ADRC. We have a large and growing pool of training grant eligible trainees who are attracted by the diverse and growing portfolio of NIH funded research. Our training approach includes a dual mentorship plan (i.e., basic and clinical mentors) for full-time trainees that is structured as an Individual Development Plan to encourage multidisciplinary and translational approaches. The program is designed to provide the skills needed to develop an independent research career in ADRD research through 4 objectives: 1) provide a broad ADRD foundation with exposure to diverse research approaches (basic, clinical, and translational) and clinical care (patients and caregivers), 2) develop ADRD research skills (basic, clinical, and translational), 3) develop multidisciplinary research skills to foster collaborations among trainees and mentors, and 4) develop presentation and grant-writing skills. The summer training program is designed to expose clinical students to ADRD research and clinical care to foster interest in careers in ADRD research. The training program leverages institutional resources and the KU ADRC's research strengths to create a developmental pathway for the next generation of ADRD basic, translational, and clinical scientists. T32 funding will provide critical support to synergize with ongoing institutional efforts, further enhance the ADRC's training efforts, and draw on the center's unique resources, exceptional mentors, supportive collaborators, and growing breadth of educational opportunities.